Follica Update R&d & Capital Markets Day( (may 12th 2017)

[Xaser94]

http://cache.merchantcantos.com/webcast/webcaster/4000/7464/16531/85401/Lobby/default.htm

In order to listen to the webcast you must sign up. It takes about two seconds. Information about Follica starts at about the one hour mark. The unfortunate news is that they still have not started their optimization study or pivotal trial yet. On the slide where they talk about the drug compound they have a picture of foam (so probably minoxidil), and they also have a picture of a dropper (dripping a liquid, could be minoxidil as well).

They still did not specifically state what drug compound they are using but they did confirm that they are working on their own compounds for Follica as well. This was the most intersting slide as they specify their device is a "HFN device," dont really know what that is. They also state that they are developing next generation of novel follicular neogenesis compounds which are pre clinical as of now. Unfortunately there is no date for when they will be using those.

Hopefully I did not misunderstand anything. Im hoping you guys listen to the webcast and let me know if im wrong about anything. Thanks.


Edit: HFN device = hair follicle neogenesis device? Thoughts?

 

[Agent]

Sigh! No trial yet...f*****g endless shitstorm of depressing news. Little hard to get pumped over some foam and a dripper...
@Xaser94, thanks for posting anyways, appreciated.

 

[Royaume]

Sigh! No trial yet...f*****g endless shitstorm of depressing news. Little hard to get pumped over some foam and a dripper...
@Xaser94, thanks for posting anyways, appreciated.

They said about a month ago that they will begin their phase 3 study in second half of 2017... Why so upset? It was in their company summary pdf. Maybe they start next month?

 

[Follisket]

Sounds a bit crude if it really is just Minoxidil, doesn't it? I mean, you take two existing treatments, put them together, release them on the market as a new product and that's it? Hard to imagine any kind of dramatic results with just that.

 

[Swoop]

Nice find as always Xaser94.

But yeah minoxidil brahs. Easy prediction.

R. Dhurat GOD.

 

[Agent]

Nice find as always Xaser94.

But yeah minoxidil brahs. Easy prediction.

R. Dhurat GOD.

I hope your wrong @Swoop, but unfortunately everything points towards minoxidil:-/ Their whole disruption procedure will hopefully surprise us all with magnificent results :-O

 

[Swoop]

I hope your wrong @Swoop, but unfortunately everything points towards minoxidil:-/ Their whole disruption procedure will hopefully surprise us all with magnificent results :-O

Hehe but like I told you, the REAL mastermind behind microneedling + minoxidil (which Follica will be basically) is R. DHURAT (FOLLICA ADVISOR)!

 

[Royaume]

Nothing new but does this mean that they are still able to create 19 hairs per cm²?....

 

[lynney45]

View attachment 53175

Nothing new but does this mean that they are still able to create 19 hairs per cm²?.... View attachment 53175

I am struggling to see how 19 hairs per cm2 is going to have any cosmetic benefit? I mean even if this treatment was on the market today wouldn't low norwoods prefer to have a hair transplant for greater density and cosmetic benefit than can be achieved with follica?

 

[what]

I'm curious to know if these neogenic hairs will have a local effect on the scalp environment. Would their presence affect the scalp environment and make it less hostile for hair growth such that neighboring hairs undergoing miniaturization might be reversed or saved, so to speak. Maybe it could even prevent further balding in total. That would be huge.

Even if the procedure only produces 19 hair/cm^2 new terminals, it could be combined with a hair transplant for a great result, even for higher Norwood guys.

Based on Dhurat's papers, it seems like these trials should be in the 3 to 6 months range in duration. So if they got the optimization trial started by June, it could be done by the end of the year or sooner. Then go right into the final trial. They could be ready to roll out Mid 2018 if things go as planned.

 

[pegasus2]

View attachment 53175

Nothing new but does this mean that they are still able to create 19 hairs per cm²?.... View attachment 53175

This is 19x, not 19 hairs. I think it just means modality 5.1 is 19x as effective as modality 1. I thought they said before it was around 100 hairs/cm², including vellus.

I want to know what modality 5.2 is. It must be similar to 5.1, yet it's a lot more effective.

Thanks for posting this @Xaser94. You always find the best info. HFN must be hair follicle neogenesis.

 

[Xaser94]

This is 19x, not 19 hairs. I think it just means modality 5.1 is 19x as effective as modality 1. I thought they said before it was around 100 hairs/cm², including vellus.

I want to know what modality 5.2 is. It must be similar to 5.1, yet it's a lot more effective.

Thanks for posting this @Xaser94. You always find the best info. HFN must be hair follicle neogenesis.

Thanks you and I agree completely. I also am not sure what modality 1 was, but im assuming all the previous modalities encompass all their "failed" attempts, such as the trial with lithium gluconate 8 percent gel and such. Im hoping with their optimization study they can regrow even more hair!

 

[champpy]

HFN
High frequency ?

 

[mdmnota]

Sounds a bit crude if it really is just Minoxidil, doesn't it? I mean, you take two existing treatments, put them together, release them on the market as a new product and that's it? Hard to imagine any kind of dramatic results with just that.

An it took you what, ten years?

 

[H]

I thought they said before it was around 100 hairs/cm²

Isn't that the max natural density a human can have?

 

[That Guy]

b**ch b**ch whine whine about how they're probably going to use a proven compound with the proven method of growing hair from wounding and how they still haven't started the trial even though that slide clearly states that they aim to begin in the 2nd half of this year; it's not the second half of this year yet.

Anyway, good find as usual Xaser — I for one am looking forward to more Follica news and that article about Rox Anderson had said that they plan to release some of their data.

 

[Dolph]

Are they actually measuring follicles or can a "neogenic structure" be something else?

We'll see what they end up with. Like others, I'm planning for the worst and assuming Follica will end up being Pilox 2.0.

 

[Swoop]

Are they actually measuring follicles or can a "neogenic structure" be something else?

We'll see what they end up with. Like others, I'm planning for the worst and assuming Follica will end up being Pilox 2.0.

I agree. As always with Follica they project themselves as a weak cuckold company. Zero evidence, and laughable talks.

I don't understand why people wait for Follica though.

Why don't you all just pick up microneedling + minoxidil as per the R. Dhurat protocol?

It's not like Follica will come out with something way more advanced than that.

 

[mghrs]

this 19 + 80 vellus is going to be an addition to what you have and if compoundable through multiple treatments it will be even better. you can combine it with transplants if you wish.
we need more clarification on:
they said they needed 1 more study before now they need 2,why ?
and what does the 2 studies mean for their timeline then, late 2019 ?
are they attending japan hair congress? if so, wee need to ask them about this and some before and after at this point would be really great or at least more about efficacy.

 

[mghrs]

I agree. As always with Follica they project themselves as a weak cuckold company. Zero evidence, and laughable talks.

I don't understand why people wait for Follica though.

Why don't you all just pick up microneedling + minoxidil as per the R. Dhurat protocol?

It's not like Follica will come out with something way more advanced than that.

was that protocol able to create new follicles or just enhance minoxidil results by thickening existing hair. I believe it is the latter