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It should be an important study in the treatment of alopecia and hair loss. Source / Dr. Sara Wickström
● hair loss might be prevented by regulating stem cell metabolism
● Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle
● The stem cells were caused by a loss of metabolic flexibility.
● that stem cells and daughter cells have distinct metabolic characteristics,
● Our analyses further predicted that Rictor, an important but relatively poorly understood molecular component of the metabolic master regulator mTOR pathway, would be involved
● The key finding of this study is that this so-called fate reversibility requires a shift from glutamine metabolism and cellular respiration to glycolysis
● That application of a glutaminase inhibitor was able to restore stem cell function in Rictor-deficient mice.
www.helsinki.fi
It should be an important study in the treatment of alopecia and hair loss. Source / Dr. Sara Wickström
● hair loss might be prevented by regulating stem cell metabolism
● Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle
● The stem cells were caused by a loss of metabolic flexibility.
● that stem cells and daughter cells have distinct metabolic characteristics,
● Our analyses further predicted that Rictor, an important but relatively poorly understood molecular component of the metabolic master regulator mTOR pathway, would be involved
● The key finding of this study is that this so-called fate reversibility requires a shift from glutamine metabolism and cellular respiration to glycolysis
● That application of a glutaminase inhibitor was able to restore stem cell function in Rictor-deficient mice.
A study indicates that hair loss might be prevented by regulating stem cell metabolism | University of Helsinki
An international research group headed by Associate Professor Sara Wickström at the University of Helsinki has identified a mechanism that is likely to prevent hair loss.