How much is Dutasteride more powerful than Finasteride

J.WayneUK

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Thinking about THE switch (to Duta of course)... should I expect noticeable results if I do it, since i'm 22 and started finasteride in May 2015 - almost a year then?
 

transam

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Thinking about THE switch (to Duta of course)... should I expect noticeable results if I do it, since i'm 22 and started finasteride in May 2015 - almost a year then?
dutasteride is more potent in sides & DHT suppression. How much more potent?...some kind of fancy percentages I'm sure...
I've been on finasteride for 11 months with results lower than expected. So I'm now taking dutasteride & finasteride. Don't wanna drop the finasteride
 

Ben13738

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Finasteride reduces DHT levels by around 60% I believe, and dutasteride reduces DHT levels by around 90% I think. Not entirely sure they're 100% correct though.
 

RD03

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1mg Finasteride supresses Type II 5 alpha reductase isonenzyme by 90-92% when it hits plateau. Dutasteride does by 98-99%. It's not scalp DHT or serum DHT that matters.

Dutasteride is basically a bulletproof solution to male pattern baldness in terms of holding male pattern baldness from progressing.
 

RD03

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I suggest you search some of Bryan's old posts. He has plenty of information on this subject and studies linked it to. I can't find the studies right now as I am not home. Don't listen to K9gatton he is giving you the wrong information and most people on these forums have no idea what the actual difference in Finasteride and Dutasteride is.

There's no difference in liquid finasteride... and I have no idea where he comes up with this idea. Finasteride hits a plateu around 5mg regardless of form.

Read this study http://www.bernsteinmedical.com/resources/hair-restoration-papers/dutasteride-vs-finasteride/ although not from ncbi, it shows you the different numbers. However, serum DHT is not important, the main reason dutasteride is better than finasteride at supressing serum DHT is due to the fact it also inhibits type Type I 5 alpha reductase isonenzyme, but this has no correlation with hair loss. You can see that in the study developed by Merck where they have a specific substance that inhibits only type I and they found no correlation to hair loss.

However Type II is important, and the Pseudohermaphrodites who lack this specific isoenzyme has no hair loss; hence you need to focus on the amount of type 2 dht that finasteride and dutasteride supresses.
 

kj6723

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I suggest you search some of Bryan's old posts. He has plenty of information on this subject and studies linked it to. I can't find the studies right now as I am not home. Don't listen to K9gatton he is giving you the wrong information and most people on these forums have no idea what the actual difference in Finasteride and Dutasteride is.

There's no difference in liquid finasteride... and I have no idea where he comes up with this idea. Finasteride hits a plateu around 5mg regardless of form.

Read this study http://www.bernsteinmedical.com/resources/hair-restoration-papers/dutasteride-vs-finasteride/ although not from ncbi, it shows you the different numbers. However, serum DHT is not important, the main reason dutasteride is better than finasteride at supressing serum DHT is due to the fact it also inhibits type Type I 5 alpha reductase isonenzyme, but this has no correlation with hair loss. You can see that in the study developed by Merck where they have a specific substance that inhibits only type I and they found no correlation to hair loss.

However Type II is important, and the Pseudohermaphrodites who lack this specific isoenzyme has no hair loss; hence you need to focus on the amount of type 2 dht that finasteride and dutasteride supresses.

"The only subject to develop gynecomastia was in the placebo group."

Wtf lol
 

RD03

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"The only subject to develop gynecomastia was in the placebo group."

Wtf lol

Yup... You'll see that Dutasteride, at least in some studies, shows less frequency in terms of side effects. And if you read more stuides you'll see that the placebo group sometimes experience more side effects than the focus group.

That's why I always tell people to put their mind of these side effects, I believe most finasteride side effects are nosebo.
 

kj6723

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Yup... You'll see that Dutasteride, at least in some studies, shows less frequency in terms of side effects. And if you read more stuides you'll see that the placebo group sometimes experience more side effects than the focus group.

That's why I always tell people to put their mind of these side effects, I believe most finasteride side effects are nosebo.

So some dude worried his way into growing tits?
 

kmm179

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Yeah placebo effects is intense. I guarantee that a good portion of sides reported are that. The dudes who are worried before they take it/constantly looking for them. Like if that dude Pavi took finasteride I would say there's like a 80% chance he would report a side bc he's so worried about the subject.
The mind can literally have a physical impact on the body.
 
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