G
Guest
Guest
I belive that it has to do with the placement of the follicles in the scalp and physical space.
The culprit - Follicle placement and physical space.
The actors - DHT and sebum.
The end - Fibroblasts.
The waste - Topical DHT inhibition.
The joker - Topical fibroblast inhibition.
Finally minoxidil - why it works.
Start: We get born and the body develops, follicles are placed and hair grows thanks to the direct or indirect effect of androgens. As we hit puberty the physical space of the scalp is more or less "fixed".
This is when the problem starts - puberty. The increased secretion of androgens lead to an excess production of Sebum and start of our problems. Sebum could be a buildingblock or a trigger for hairgrowth but when in excess amounts it cloggs up the scalp leading to increased pressure - this leads to decreased scalpflow.
What then can´t flow? well it could be blood, it could be lymph I really don´t know. What I´m really suspecting is that the decreased flow leads to pressure buildup and eventually cellular death beacuse of physical pressure.
What supports this? Well 1) Scalp pain and itch - inflammation 2) Greasy scalp - Excess sebum.
First problem:
What about transplanted hairs? Well as we all know even transplanted hairs tend to follow the path of original hair but it´s pretty safe to assume that if you had 100 follicles producing sebum in 1square cm (this nr is totally fictional) and instead have 10 follicles much less sebum will be produced and less physicla pressure. Of course there will be the collagen and the scartissue but still it´s less then originally.
Second problem:
What about the DHT inscensitive hair? I don´t belive there is any DHT inscensitive hair. I belive that the sides and the back of your head have much better cirkulation and the follicles are further apart - there is never an equally strong pressure buildup.
Third problem:
finasteride helps which means DHT is EVIL. Well too much DHT in a tight scalp will via sebum cause an inflammation that kills your follicles but without DHT your hair will go limp. Did you ever consider the random sheds? well my friends could is it a coincidence that just when things feel great one hell of a shed hits - it´s because the follicles can´t hold onto the hair when the level of DHT hits rock bottom. Any other shed explanation is just fiction.
Topicals help: If you had a topical that would alter the level of sebum so it matched the physical space of your scalp then yes topicals work - so far the topicals we have DON´T WORK. Ok they could work but it´s like winning the lottery because you have to match the application of the topical with the peak DHT production and then the level has to drop so you get an amount of DHT that is needed for hairgrowth.
Fourth problem:
How can women have hair if they have no DHT? Well how the hell should I know. Maybe, just maybe it´s the effect of female sexhormones. Women are different then men in many ways and why a direct parallel should be drawn is just beyond me.
Finally I will get into why minoxidil works and some other issues.
minoxidil works by increasing scalp cirkulation - thus taking away some pressure and letting the follicles work. Easy? yepp. Will minoxidil work with everyone? well yes. It will but consider this. If sebum causes an 200% increase in scalp pressure (again fictional figure) and minoxidil will increase cirkulation by 50% then you still have 150% excess and you will see no difference. So it´s all about physical space.
Does this happen anywhere else in the body? Consider what happens if the duct leading from the pancrease to the duodenum is restricted. The backward flow of pancreatic juice will cause an inflammed pancreas and cellular death. The same goes with the liver if the hepatic duct is restricted - backward flow, increased pressure and cellular death.
Fibroblasts. They lay down a carpet of collagen which can´t be removed, like any scar tissue it will be reduced with time but never completely and once you have scar tissue then the physical space is limited irreversibly.
The pattern: Just like people have the same types of noses, lips, eyes etc they have similar scalps. Some people get the receeding hairline some get the diffuse thinning. Oh and why I mean scalps I mean both physical space and the network of vessels for lymph and blood. How else do you explain the different patterns of balding? Do DHT sensitive and not sensitive follicles mix during embryogenesis? ... That would make NO sense.
Quick summary: Without DHT no hair. Too much DHT with a tight scalp - inflammation - hairloss.
Think about this: They have found no difference between body hair and scalp hair follicles but it´s really easy to assume that the body has better cirkulation then the scalp.
How to avoid hairloss?
I see only one way - lower your body testosterone. How? I don´t know. I´m doing it by malnutrition and heavy cardio. My hair is doing really great and my scalp feels amazing. I´m slowly eating more but as soon as I feel an increased "wetness" I eat less and work hard. This will effect your libido but that´s something I chose. I can have sex but I just don´t feel like it as often.
I used to be on the big three. I first ditched nizoral about 5 months ago - never used it since. I also ditched minoxidil about a month ago and since then my scalp feels alot better and I´m not talking about itch, itch is something I could live with but the feeling of a small bruise bothered me.
Warning - I´m not telling people to stop using minoxidil. It helps cirkulation. However I´m worried abou the carrier upregulating TGF-b which stimulate fibroblasts.
Thanks for reading.
The culprit - Follicle placement and physical space.
The actors - DHT and sebum.
The end - Fibroblasts.
The waste - Topical DHT inhibition.
The joker - Topical fibroblast inhibition.
Finally minoxidil - why it works.
Start: We get born and the body develops, follicles are placed and hair grows thanks to the direct or indirect effect of androgens. As we hit puberty the physical space of the scalp is more or less "fixed".
This is when the problem starts - puberty. The increased secretion of androgens lead to an excess production of Sebum and start of our problems. Sebum could be a buildingblock or a trigger for hairgrowth but when in excess amounts it cloggs up the scalp leading to increased pressure - this leads to decreased scalpflow.
What then can´t flow? well it could be blood, it could be lymph I really don´t know. What I´m really suspecting is that the decreased flow leads to pressure buildup and eventually cellular death beacuse of physical pressure.
What supports this? Well 1) Scalp pain and itch - inflammation 2) Greasy scalp - Excess sebum.
First problem:
What about transplanted hairs? Well as we all know even transplanted hairs tend to follow the path of original hair but it´s pretty safe to assume that if you had 100 follicles producing sebum in 1square cm (this nr is totally fictional) and instead have 10 follicles much less sebum will be produced and less physicla pressure. Of course there will be the collagen and the scartissue but still it´s less then originally.
Second problem:
What about the DHT inscensitive hair? I don´t belive there is any DHT inscensitive hair. I belive that the sides and the back of your head have much better cirkulation and the follicles are further apart - there is never an equally strong pressure buildup.
Third problem:
finasteride helps which means DHT is EVIL. Well too much DHT in a tight scalp will via sebum cause an inflammation that kills your follicles but without DHT your hair will go limp. Did you ever consider the random sheds? well my friends could is it a coincidence that just when things feel great one hell of a shed hits - it´s because the follicles can´t hold onto the hair when the level of DHT hits rock bottom. Any other shed explanation is just fiction.
Topicals help: If you had a topical that would alter the level of sebum so it matched the physical space of your scalp then yes topicals work - so far the topicals we have DON´T WORK. Ok they could work but it´s like winning the lottery because you have to match the application of the topical with the peak DHT production and then the level has to drop so you get an amount of DHT that is needed for hairgrowth.
Fourth problem:
How can women have hair if they have no DHT? Well how the hell should I know. Maybe, just maybe it´s the effect of female sexhormones. Women are different then men in many ways and why a direct parallel should be drawn is just beyond me.
Finally I will get into why minoxidil works and some other issues.
minoxidil works by increasing scalp cirkulation - thus taking away some pressure and letting the follicles work. Easy? yepp. Will minoxidil work with everyone? well yes. It will but consider this. If sebum causes an 200% increase in scalp pressure (again fictional figure) and minoxidil will increase cirkulation by 50% then you still have 150% excess and you will see no difference. So it´s all about physical space.
Does this happen anywhere else in the body? Consider what happens if the duct leading from the pancrease to the duodenum is restricted. The backward flow of pancreatic juice will cause an inflammed pancreas and cellular death. The same goes with the liver if the hepatic duct is restricted - backward flow, increased pressure and cellular death.
Fibroblasts. They lay down a carpet of collagen which can´t be removed, like any scar tissue it will be reduced with time but never completely and once you have scar tissue then the physical space is limited irreversibly.
The pattern: Just like people have the same types of noses, lips, eyes etc they have similar scalps. Some people get the receeding hairline some get the diffuse thinning. Oh and why I mean scalps I mean both physical space and the network of vessels for lymph and blood. How else do you explain the different patterns of balding? Do DHT sensitive and not sensitive follicles mix during embryogenesis? ... That would make NO sense.
Quick summary: Without DHT no hair. Too much DHT with a tight scalp - inflammation - hairloss.
Think about this: They have found no difference between body hair and scalp hair follicles but it´s really easy to assume that the body has better cirkulation then the scalp.
How to avoid hairloss?
I see only one way - lower your body testosterone. How? I don´t know. I´m doing it by malnutrition and heavy cardio. My hair is doing really great and my scalp feels amazing. I´m slowly eating more but as soon as I feel an increased "wetness" I eat less and work hard. This will effect your libido but that´s something I chose. I can have sex but I just don´t feel like it as often.
I used to be on the big three. I first ditched nizoral about 5 months ago - never used it since. I also ditched minoxidil about a month ago and since then my scalp feels alot better and I´m not talking about itch, itch is something I could live with but the feeling of a small bruise bothered me.
Warning - I´m not telling people to stop using minoxidil. It helps cirkulation. However I´m worried abou the carrier upregulating TGF-b which stimulate fibroblasts.
Thanks for reading.
