If A Cure Were To Come Out Soon, What Do You Think It Would Be?

[H]

That seems like a rather arbitrary line of demarcation...

It is lol everyone's situation is different and I have probably a different view of what constitutes as acceptable regrowth and coverage than others its just my opinion. I don't see follica and Replicel filling in bald spots or sparse diffuse hair already back to what looks to be non thinning hair at all but they both aren't out so I can't be for sure. No one can answer this threads question objectively.

 

[NewUser]

Gene therapy and gene editing would be extreme measures that may not be necessary for pattern baldness given the amount of knowledge of HF gained in recent years, Hair biologists are understanding more of the transcription factors and signalling pathways affecting hair loss that I am betting geneticist Angela Christiano's prediction will prove correct. The cure will be an inexpensive OTC topical cream or ointment. She said that years before these latest discoveries for Krox20, SCF, and now lactate.

 

[Trichosan]

I was talking with a biochemist last week doing research on telomerase. He stated they are seeing success in the application of modified extranuclear dna. If this is the case then the tools are at hand once the critical genes for hair vs no hair are found. My point is, they are much more advanced on genetic modification than I suspected. And hopefully more in hair growth research than we are privy to.

 

[H]

Gene therapy and gene editing would be extreme measures that may not be necessary for pattern baldness given the amount of knowledge of HF gained in recent years, Hair biologists are understanding more of the transcription factors and signalling pathways affecting hair loss that I am betting geneticist Angela Christiano's prediction will prove correct. The cure will be an inexpensive OTC topical cream or ointment. She said that years before these latest discoveries for Krox20, SCF, and now lactate.

Heh? If by cure you mean maintenance I can see that.

 

[c_super2]

I remember guys where so full of hope back in 2003-2006 for HM. I was ALWAYS skeptical because there was no real science to back it up except for sensationalist claims by Dr. Gho. I am amazed how much better hair loss knowledge has advanced since there. Literally, back then the only thing we knew about what caused hair loss was DHT. We didn't even have a single gene down. Now, we know SOOOO much more and the companies claims are based on good science which sounds reasonable. Given this, I am positive that replicel will come out and tsjui will come out close to his timeline. However, to the guys saying that gene editing will come out 3-4 years after Tjsui reminds me of the guys way back when predicting when HM would come out. There is really nothing to base these claims on, so I am not going to trust them or hold my breathe that it will come out so soon.

 

[sangan89]

HISTOGEN? Seriously? Histogen is f*****g dead alredy

 

[Endmymisery]

Whatever happened with histogen?

 

[MrV88]

Their most recent news was in July, something about skin care though.

http://www.histogeninc.com/aboutus/news_events.htm#58

Srsly they were very promising...

http://www.histogeninc.com/applications/hsc.htm

Clinical Development
Two proof-of-concept clinical trials of an earlier prototype of CCM were completed outside the US, revealing promising efficacy results. In one trial, 84.6% of patients receiving just one treatment showed a significant increase in terminal hair count and hair thickness at 12 weeks. Improvement of hair growth parameters was still evident after one year.

In the second clinical trial, in which patients received two treatments 6 weeks apart, the increase in total hair count was 46.5% above that seen after a single treatment. Significant improvements were observed in total hair count, terminal hairs and hair thickness at 12 weeks. At one year, hair growth parameters remain substantially above baseline.

Didn't histogen clearly said to their investors that their product will not be available before 2019?

 

[That Guy]

I am also for the Follica + Shiseido camp.

I don't see any reason why a combination therapy of the two shouldn't be able to act as a functional cure for most and it's a stone-cold fact that they're the only things that should be on the market before next decade.

Tsuji, assuming his method for cell cultivation works on human cells, is still years away from being a realistic option for the masses and there is no way CRISPR would do anything for the already-bald people and it's years away as is — I count neither of these things as "soon".

and everything else is irrelevant.

 

[MrV88]

A combination of velus and terminal hairs of 25-100/cm² from Follica and 25-100/cm² from Shiseido and getting the velus permanent and thick could be basically a full head of hairs again. Even if they don't get over 100 think about the possibility of donor restoration of both. Like that guy says it's very close to a cure.

Limited/semi-endless supply of new follicles and getting thin hairs back would be enough for NW1-4

AND it's repeatable!

 

[Endmymisery]

A combination of velus and terminal hairs of 25-100/cm² from Follica and 25-100/cm² from Shiseido and getting the velus permanent and thick could be basically a full head of hairs again. Even if they don't get over 100 think about the possibility of donor restoration of both. Like that guy says it's very close to a cure.

Limited/semi-endless supply of new follicles and getting thin hairs back would be enough for NW1-4

AND it's repeatable!

Aren't you guys being a little too optimistic?

 

[MrV88]

Aren't you guys being a little too optimistic?

Follica claims 25 terminal 75 velus. İf Shiseido is able to make those terminal we could have 100 in total and that's if Shiseido doesn't add anything, which I think it will do.
İf you still have 50-100 left on your head it would be quite good. You are back to 150-200cm², much better than 0

The best point is that both of them could regrow hair in your donor area, so you could even get a good transplant, get your hairs back (donor) at a certain percentage and still grow some new hair on your reception area.

I wasn't optimistic about Follica, but 38 patents and like noisette suggested it's much more than just minoxidil and microneedling.

About Shiseido? Well it's mutiplication, anything that mutiplies my donor hair has to be somehow great. At the end it ain't any jungle juice, foreskin cream or oil complex.

I need the "it's science b**ch" meme here

The only thing I'm note sure is when Follica will be available, still believe in Shiseido for end of 2018.

Tsuji ist just ludicrous mode and will make us Chewbacca, even if we didn't have good hair from the beginning

 

[Endmymisery]

Follica claims 25 terminal 75 velus. İf Shiseido is able to make those terminal we could have 100 in total and that's if Shiseido doesn't add anything, which I think it will do.
İf you still have 50-100 left on your head it would be quite good. You are back to 150-200cm², much better than 0

The best point is that both of them could regrow hair in your donor area, so you could even get a good transplant, get your hairs back (donor) at a certain percentage and still grow some new hair on your reception area.

I wasn't optimistic about Follica, but 38 patents and like noisette suggested it's much more than just minoxidil and microneedling.

About Shiseido? Well it's mutiplication, anything that mutiplies my donor hair has to be somehow great. At the end it ain't any jungle juice, foreskin cream or oil complex.

I need the "it's science b**ch" meme here

The only thing I'm note sure is when Follica will be available, still believe in Shiseido for end of 2018.

Tsuji ist just ludicrous mode and will make us Chewbacca, even if we didn't have good hair from the beginning

Yeah but looking at really old posts where they had similar optimism which only resulted in crushed hope and despair , I'm kind of feeling pessimistic...
I still do believe in shiseido and in time, Tsuji but I don't have the same confidence for Follica, I hope I am wrong tho about Follica.

 

[MrV88]

Yeah but looking at really old posts where they had similar optimism which only resulted in crushed hope and despair , I'm kind of feeling pessimistic...
I still do believe in shiseido and in time, Tsuji but I don't have the same confidence for Follica, I hope I am wrong tho about Follica.

Let's see if they become available before Tsuji or ever, I think that is the important point.
We'll see and have nothing but hope

 

[H]

İf you still have 50-100 left on your head it would be quite good. You are back to 150-200cm², much better than 0

Better than 0 lol that would literally be all of your hair back I'm pretty sure. There's absolutely no guarantees it'll actually bring back that much hair but we'll just have to see.

 

[MrV88]

Better than 0 lol that would literally be all of your hair back I'm pretty sure. There's absolutely no guarantees it'll actually bring back that much hair but we'll just have to see.

50 hairs left that get immunized by Shiseido, 50 from Follica and Shiseido combined and 50 from a transplant makes at least 150...deal?

 

[H]

50 hairs left that get immunized by Shiseido, 50 from Follica and Shiseido combined and 50 from a transplant makes at least 150...deal?

Shake on it?

 

[MrV88]

Shake on it?

Ok the deal is sealed

 

[Trichosan]

That's crazy, sci-fi is becoming reality.

Just wonder when (or even if) it will launch commercially.

Safety and efficacy are about two years away, so he said, but the biggest impediment to fruition is time and money for the FDA.

 

[Trichosan]

...
Tsuji ist just ludicrous mode and will make us Chewbacca, even if we didn't have good hair from the beginning

Good. I need 75,000 hairs to get back 40 years of loss.