If spironolactone is so good, why hasn't there been any tests for male pattern baldness

mgdpublic

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Hey, I'm using it myself so I ain't knocking it. But Dr. Lee seems to think it's more effective than propecia. Why hasn't this stuff received any respect in the research area for male pattern baldness?
 

The Gardener

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Well, for one, it COULD be that clinical trials cost money. For a pharma company to do a trial means cash investment would be needed, which means they would have to raise the prices of the product once the trial is complete ASSUMING is is successful.

Would you buy spironolactone from one particular pharma company at a higher price, just because that pharma company's spironolactone has a "the government says that this works" claim on the label?
 

drinkrum

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Re: If spironolactone is so good, why hasn't there been any tests for

mgdpublic said:
Hey, I'm using it myself so I ain't knocking it. But Dr. Lee seems to think it's more effective than propecia. Why hasn't this stuff received any respect in the research area for male pattern baldness?

I reckon there have been trials -- they basically indicated that spironolactone needed to be applied once every few hours to be effective against male pattern baldness. Once a day might not really be enough.

D.
 

Redbone

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My jury is still out on spironolactone hasnt done sh*t for me in the month I have been non it. Just made my head smell like a damn skunk. Still serious recession at temples
 

Bryan

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Re: If spironolactone is so good, why hasn't there been any tests for

drinkrum said:
I reckon there have been trials -- they basically indicated that spironolactone needed to be applied once every few hours to be effective against male pattern baldness.

I haven't seen any such trials that supposedly indicated that, and I _believe_ I have almost every topical spironolactone study ever published. All the ones I've seen (with both humans and animals) applied the stuff either once or twice a day, and sometimes only just 5 days a week.

Bryan
 

Odelay

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True the trials to get FDA approval will cost a lot money, but if his product was backed and proven to work he would make a ton of money on the stuff. So the only reason not to try and get it approved would be because he is either afraid it won't get approved or he is not a fan of making money.
 
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redbone said:
My jury is still out on spironolactone hasnt done sh*t for me in the month I have been non it. Just made my head smell like a damn skunk. Still serious recession at temples

You should know that any good treatment requires time to work. And even if it doesn't work on you, it doesn't mean that the product doesn't work at all.
 

mgdpublic

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Rubber Baby Buggy said:
Not a big fan of Lee and his products, but don't won't to step on any toes so soon so I won't go into detail.

It's an open forum; you won't be stepping on any toes. That's why this forum is here. If you know/think something, share it.
 

Bryan

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Odelay said:
True the trials to get FDA approval will cost a lot money, but if his product was backed and proven to work he would make a ton of money on the stuff. So the only reason not to try and get it approved would be because he is either afraid it won't get approved or he is not a fan of making money.

I'm baffled by your reasoning, specifically the claim that he would "make a ton of money" if his spironolactone products got FDA approval. Topical minoxidil has FDA approval and has been proven to work by studies from all over the world, right? Has it made "a ton of money" for Upjohn? The answers to those questions are yes and no, respectively.

Spironolactone lost its patent protection years and years ago. Nobody, repeat NOBODY is going to spend huge amounts of $$$ for FDA approval for a new indication for an ancient drug which has long since lost its patent protection, and which probably stimulates even less regrowth than Rogaine. Ain't gonna happen.

There are good theoretical reasons and even a smattering of clinical trials to show that topical spironolactone is helpful for fighting male pattern baldness, but it will never ever see the light of day of FDA approval for that purpose.

Bryan
 

Rubber Baby Buggy

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mgdpublic said:
It's an open forum; you won't be stepping on any toes. That's why this forum is here. If you know/think something, share it.

I have seen how it all starts, you say your true feelings on this site then you get people that will start with the name calling and the arguing. Then you have people that want to challenge you to a debate over your beliefs, it's not worth the hassle.
 

RalphyWiggum

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redbone said:
My jury is still out on spironolactone hasnt done sh*t for me in the month I have been non it. Just made my head smell like a damn skunk. Still serious recession at temples

I too am surprised that someone with as many posts as you would make such a comment :x .

You should know better :adminfinger:

You have to give hair loss treatments at least six months (my rule is year) before making any kind of judgements about personal efficacy.
 
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