Is Taking 0.25mg Of finasteride Worth It?

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Im on revivogen and minoxidil now, but im thinking of adding something else.Would 0.25mg of finasteride be worth it? Or is that just a waste of time?I have been on propecia in the past and got sexual sides even at 0.5mg,Will 0.25mg be better?
 
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has anyone here had sides from 1mg dose then switched to 0.25 and had no sides at all? not even lowered sex drive?
 

ali777

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I tried 1/4 finasteride for 3-4 days. I felt like the side effects were less, but it might be just me... You have to try it for yourself to find out.

On the other hand, search the forum, there is a study somewhere that shows the effectiveness of 0.2 and 1mg finasteride are similar. Theoretically, 0.25 should be an efficient treatment.
 
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I just ordered some finpecia,Hopefully at 0.25 i wont have any sides.I just want to be able to quit rogaine,This facial water retention is really making my face ugly.
 

stampede

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Finasteride reduces DHT by stopping 5ar doing its job.

It's the reduction in DHT which causes your hair to grow and your sides to develop. I reckon there won't be a lot of difference, as 0.25mg reduces DHT by almost as much as 1mg.

Worth a try though, and will obviously be a quarter of the financial cost :)
 
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Wrong again as usual.0.25 will have heaps lower side effects than 1mg.It would probably block enouth dht to stop hairloss but not enouth to destroy libido,They arnt one in the same,I dont care what bryan says,he doesnt know everything.
 

Bryan

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Davidoff said:
Wrong again as usual.0.25 will have heaps lower side effects than 1mg.

How do you know that? What leads you to believe that?
 
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Because of case reports of people who got sides from 1mg and then cut down to 0.25 and experienced none.I would like to know how you know there would be no difference? I think 0.25mg is probably enouth for them to stop hairloss but not high enouth to reduce sex drive.I dont think you need as much finasteride to stop hairloss as you do to chemically induce sexual side effects.
 

Bryan

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Davidoff said:
Because of case reports of people who got sides from 1mg and then cut down to 0.25 and experienced none.I would like to know how you know there would be no difference?

I don't claim to know that there would be no difference, but considering how similarly the two doses suppress DHT, I think it would be unlikely that anybody could distinguish such small differences.

I have to smile when I read about somebody taking a somewhat smaller dose of finasteride, and suddenly their "side effects" magically disappear! I think a lot of that is in a person's head! :) I'm reminded of that recent study in which finasteride users reported a lot more sexual "side effects" when the possibility of that happening was discussed with them beforehand. The ones who were simply given the drug without that discussion beforehand reported a lot fewer such "side effects"! :)

Davidoff said:
I think 0.25mg is probably enouth for them to stop hairloss but not high enouth to reduce sex drive.I dont think you need as much finasteride to stop hairloss as you do to chemically induce sexual side effects.

Interesting speculation, but that's all it is: speculation. For all we know, it might be the opposite of that.
 

goata007

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Bryan, I just want to confirm one thing. I read somewhere that body adjusts to finas overtime by becoming making androgen receptors more sensitive to available dht, and thats why finas looses its effectiveness after few years. Do you know of any study that talks about this in detail?
 

Bryan

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The upregulation of androgen receptors in the scalp hair follicles of finasteride users was reported informally by Sawaya at a medical conference. As far as I know, it's never been reported in a medical journal article or study.

BTW, even if what she said is correct, I don't know that that accounts for the alleged "loss of effect" of finasteride after a few years. The AR upregulation is almost certainly something that happens right away, like in days or weeks, not years.
 
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Bryan said:
Davidoff said:
Because of case reports of people who got sides from 1mg and then cut down to 0.25 and experienced none.I would like to know how you know there would be no difference?

I don't claim to know that there would be no difference, but considering how similarly the two doses suppress DHT, I think it would be unlikely that anybody could distinguish such small differences.

I have to smile when I read about somebody taking a somewhat smaller dose of finasteride, and suddenly their "side effects" magically disappear! I think a lot of that is in a person's head! :) I'm reminded of that recent study in which finasteride users reported a lot more sexual "side effects" when the possibility of that happening was discussed with them beforehand. The ones who were simply given the drug without that discussion beforehand reported a lot fewer such "side effects"! :)

Davidoff said:
I think 0.25mg is probably enouth for them to stop hairloss but not high enouth to reduce sex drive.I dont think you need as much finasteride to stop hairloss as you do to chemically induce sexual side effects.

Interesting speculation, but that's all it is: speculation. For all we know, it might be the opposite of that.
I agree with the Psychosomatic theory.When i first started taking propecia years ago i didnt really have any problems,Its only when i found the internet i started to get sides. :freak:
 

goata007

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Bryan said:
BTW, even if what she said is correct, I don't know that that accounts for the alleged "loss of effect" of finasteride after a few years. The AR upregulation is almost certainly something that happens right away, like in days or weeks, not years.

What do you think/believe is the cause of finas losing effectiveness after few years?
 

Bryan

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goata007 said:
What do you think/believe is the cause of finas losing effectiveness after few years?

I don't know for sure, but I strongly suspect it has to do with continued gradual increases in the sensitivity of scalp hair follicles to androgens as the years go by (a phenomenon unrelated to the androgen receptor upregulation, as this happens in ALL men, not just the ones using finasteride).
 

Fanjeera

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Davidoff said:
I dont think you need as much finasteride to stop hairloss as you do to chemically induce sexual side effects.
I hope you're right, but I doubt it: the smart people have made a drug and assigned 1 mg as the dose. Why not make a dose, that doesn't reduce sex drive then? Lack of research?
 

treadstone

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Bryan said:
I don't know for sure, but I strongly suspect it has to do with continued gradual increases in the sensitivity of scalp hair follicles to androgens as the years go by (a phenomenon unrelated to the androgen receptor upregulation, as this happens in ALL men, not just the ones using finasteride).

Bryan, is there currently any research suggesting something that may be able to slow down this process?
 
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Fanjeera said:
Davidoff said:
I dont think you need as much finasteride to stop hairloss as you do to chemically induce sexual side effects.
I hope you're right, but I doubt it: the smart people have made a drug and assigned 1 mg as the dose. Why not make a dose, that doesn't reduce sex drive then? Lack of research?
Im not sure but i have heard people getting sides from 1mg then cutting down to 0.25mg and having none,Im just hoping this will be the case for me.
 

Bryan

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treadstone said:
Bryan said:
I don't know for sure, but I strongly suspect it has to do with continued gradual increases in the sensitivity of scalp hair follicles to androgens as the years go by (a phenomenon unrelated to the androgen receptor upregulation, as this happens in ALL men, not just the ones using finasteride).

Bryan, is there currently any research suggesting something that may be able to slow down this process?

Not to my knowledge.
 

mj9

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davidoff, why dont you just start taking 0.25 finasteride and ride it out for at least 3-4 weeks... if sides still dont go away then its up to you if you want to continue....

i had sides for 3-4 weeks but i was determined to stick to my regimen and now no sides at all!!!
 
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