Is This The Truth About Finasteride?

Falco4758

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I got my script but I just was unsure of starting it. Then I got on drugs.com and started reading reviews. They are downright scary and I won’t take it. Rather just shave my head than mess with fire. Any other thoughts on this? This is just the first page of tons of comments.does rogaine have any mental health side affects?
 

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baba_yaga

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People come here to complain. Everyone who got sides will complain and write dramatic, fear mongering stories.

FDA does not approve drugs based on users’ reviews. They rely on scientific, properly operated double-blind trials and experiments to objectively conclude a drug’s safety profile. Therefore, I advise you to read the studies and trials, and base your choice on them, not on anecdotal evidence.
 

Guglielmo123

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Everyone says the same sh*t. Its too big of a risk to take for me. I AS well have a script of finasteride that I have no taken yet hc od the potential side effects. I see more horror stories than I see Success stories. I would rather be bald than ruin my sex life, dry orgasms E.D. im good
 

Sseoud86

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Everyone says the same sh*t. Its too big of a risk to take for me. I AS well have a script of finasteride that I have no taken yet hc od the potential side effects. I see more horror stories than I see Success stories. I would rather be bald than ruin my sex life, dry orgasms E.D. im good
Lol because your am idiot. You need to log off here then because you contribute nothing but unrationalized fear. Go bald somewhere else....
 

1212

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Funny how some of those reviews say “side effects from finasteride affect way more than the 2% or 4% of people” just because the reviewer experienced side effects.

it shows how overly dramatic and irrational those reviewers are being. There’s no way you can deduce how many people are affected by sides just because you as an individual experienced side effects to whatever extent.
 

Derelict

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Stay away from scare stories and take it, if you experience sides so bad that they take precedence over your hair then just stop.
 
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NorwoodingMyWay

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Idk man, i would greatly prefer watery semen than being bald. I never heard any woman ever complain of c*m textures, or maybe i'm just ignorant and thick, white gooey c*m is what women search for these day..




If you get ED then that's another story. Eitherway, there are only 2 choices : You either 1) get scared from hearing these fearmongering anecdotes, refuse to take Finasteride while its still possible to save your hair -------> your hair gets terrible and thinner by the day, you finally decides to give finasteride a try but its way too late, and you don't get sides, which you blame yourself everyday for not trying finasteride earlier and listening to internet fears (this happens way too much).
Or 2) you try finasteride, you get sides, you quit at the first signs, you recover and either way you are at peace for trying it and seeing your unique reaction to it.
 

Falco4758

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Good points. But I suffer from migraines. So taking Aleve/Advil is very important for me and I’ve read you can’t take it on this drug? Is that true? Anyone have experience with this ?
 

Guglielmo123

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Lol because your am idiot. You need to log off here then because you contribute nothing but unrationalized fear. Go bald somewhere else....
Im an idiot for having a very rational fear when it comes to taking a prescription medication. But your not an idiot for not being able to spell "an" correctly. I see alot of you proactive finasteride dweebs insulting people on these forums who are looking for support, cut the sh*t.
 

NorwoodingMyWay

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Im an idiot for having a very rational fear when it comes to taking a prescription medication. But your not an idiot for not being able to spell "an" correctly. I see alot of you proactive finasteride dweebs insulting people on these forums who are looking for support, cut the sh*t.
Any luck with massages ??
 

Falco4758

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It shouldn't be an issue, but NSAIDs can cause hair loss. You need prostglandins for hair growth, and they inhibit them. Maybe you could take aspirin instead?

"finasteride doses of 1 mg or more were concomitantly used in clinical studies with...prostaglandin synthetase inhibitors (also referred to as NSAIDs)... without evidence of clinically significant adverse interactions."
https://www.rxlist.com/propecia-drug.htm#warnings
Wow thank you. So it’s not dangerous. Just kind of can lessen the affect of the drug?
 

bucksins6x

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For the people saying that’s it’s not dangerous, I take it you all have good results without sides right? I’m not doubting what your saying I’m just curious
 

ZZmop

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@Falco4758 You are right to be highly cautious of using this drug. I strongly recommend reading this thread before making any further decision regarding finasteride https://www.gourmetstylewellness.com/intera...-overview-of-this-devastating-disease.123852/

FDA does not approve drugs based on users’ reviews. They rely on scientific, properly operated double-blind trials and experiments to objectively conclude a drug’s safety profile.

It's true, the FDA does rely on trial data to assess a drug's safety profile. Unfortunately, some drugs pass initial safety approval tests only to subsequently be proved to be harmful, sometimes seriously so, to a subset of users. This results in label changes, including 'black box' warnings and even withdrawal from the market. As one can see from this list of withdrawn drugs https://en.wikipedia.org/wiki/List_of_withdrawn_drugs, there are well over a hundred instances of drugs being initially deemed safe, only to then be withdrawn because they were not safe.

Furthermore, the trustworthiness and veracity of the data that was submitted by Merck to the FDA has been openly dismissed in peer reviewed, published literature as recently as last month

Given that considerable level of bias is introduced in many of these studies [on finasteride] since large number of these clinical trials were funded and administered by the drug manufacturers, it is paramount that clinicians do their due diligence and not fall for the slogan, “these drugs are well tolerated and safe.”

Given the level of bias due to conflict of interest, it is not surprising that the level of harm is tampered down significantly.

Source: https://www.sciencedirect.com/science/article/pii/S0015028219325993

There is good reason that Merck's data has been dismissed. A recent article from Reuters uncovered evidence that Merck manipulated their trial data and covered up long term effects that could occur in some users https://www.reuters.com/investigates/special-report/usa-courts-secrecy-propecia/. Much of this has only now been revealed to the public because Reuters' journalists were able to unredact sections of sealed court documents from a class action lawsuit against Merck. As shown in Reuters' investigative report, there were men in the original trials who developed sexual side effects which persisted after the drug was withdrawn and Merck doesn't know if they ever resolved

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"In the fine print of Propecia's product information material there's a section called clinical trials experience. You won't find these results there. Merck doesn't disclose this data on the label that is shared with doctors and patients."

It's worth bearing in mind, these are just in regards to sexual side effects, which are just a portion of the symptoms men can and do experience with PFS.

The redacted motion argues that Merck not only underreported the number of men who experienced sexual dysfunction while taking Propecia, but also concealed the duration of those problems. Citing the Merck analyst’s memo, the motion says that of the 23 study subjects who experienced sexual side effects during the last three years of the study, seven continued to experience symptoms when they completed it. The symptoms of nine others resolved after they stopped taking the drug, but the time it took was unknown, the motion says. And of the six men who dropped out of the study, it says, one still had symptoms at least 66 days after stopping treatment.

Merck didn’t know if some of these men’s symptoms resolved, Kaufman said in a deposition.

None of this data described in the plaintiffs’ motion was included on the revised 2002 label. Instead, Merck made a small but significant change to the label’s language: Symptoms stopped in “men” who went off the pills, the label now said, rather than “all men.”

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Readers here can make up their own minds here whether they think Merck were acting in the best interests of people's health when they made such a slight of hand amendment to the label.

The full video report can be viewed here

the chances of sided are minimal. if you experience any stop taking the drug.

Stay away from scare stories and take it, if you experience sides so bad that they take precedence over your hair then just stop.

Or 2) you try finasteride, you get sides, you quit at the first signs, you recover and either way you are at peace for trying it and seeing your unique reaction to it.

I'm afraid this is outdated advice and is not accurate. If you have the predisposition to develop Post Finasteride Syndrome, once the condition has been induced by the drug, one cannot simply stop the drug and have the problem go away. This is identical advice which I read on this forum before I decided to take finasteride. I developed symptoms relating to my sleep within hours of my first dose of the drug. I continued to take the drug for another three days before I discontinued due to moderate numbing in the glans of my penis, sleep disturbances and testicular discomfort. I had taken four doses of 0.25 mg for a total of approximately 1 mg. Three days after the last dose I experienced what is referred to as the "crash". What followed in the months after was a nightmare from another dimension, an abomination for the soul to endure. There were too many symptoms to list here. I can assure you that it was far more than sexual symptoms (which I also experienced). It's nearly two years since I took 1 mg of finasteride and I still have a litany of side effects I have to deal with daily. I am no longer able to work because of them.

For the record, a 2018 literature review on the disease concluded

The occurrence of persistent adverse sexual, physical, neurological, and psychiatric side effects after 5α-reductase inhibitor is well supported by the existing data.

Source: https://link.springer.com/article/10.1007/s11930-018-0163-4

Primary data from a 2017 study found

In patients treated with finasteride for male pattern hair loss, persistent side effects may occur.
Erectile dysfunction and abnormal somatosensory evoked potentials of the pudendal nerve were reported.
Major depressive disorder and altered levels of neuroactive steroids were observed.

Source: https://www.sciencedirect.com/science/article/abs/pii/S0960076017301024

Another study

provides the first evidence of a molecular objective difference between patients with long-term adverse sexual effects after finasteride use versus drug untreated healthy controls in certain tissues.

Source: https://www.ncbi.nlm.nih.gov/pubmed/24959691
 
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Here For the Lulz

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The sides are real, the chances of experiencing them are much higher than their marketing leads you to believe, and are universally terrible. For years they were downplayed and hidden by Merck by manipulating and/or cherry picking from the studies they referenced.

The risk is still low, but not nearly as low as the 1% they threw out there. We still don’t know for sure what the actual statistics are other than that they occur in somewhere between 2% and 5%. The thing about the sides isn’t that they exist, but that all of them, including the most common ones, are potentially crippling.

You’re going to need to consider the situation to come to the decision that is right for you. Specifically, you need to decide how important is your hair to you and what you are willing to live with to keep it. Take a look at the common sides and ask yourself whether or not you could live with them were you among those who experienced them. There is no right answer to your question other than the one that applies to you.
 
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