I was all excited through the summer because people said Fidia were going to release a statement by the end of their summer holidays, unfortunately no word from them and now people are talking about November. Hopefully we'll get some info this time. 
Italian Hair Loss Lotion To Hit The Market In 2016
- Thread starter paleocapa89
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Presentation in november is about AA
Not Androgenetic Alopecia data from fedia.
Why people are waiting that presentation?
or Do I know wrong info?
Not Androgenetic Alopecia data from fedia.
Why people are waiting that presentation?
or Do I know wrong info?
- Reaction score
- 216
You are correct, but we are hoping that they mention Androgenetic Alopecia as well, even if its a small update.
Doctor brotzu say it work for both please my friends it because we wait 21 november
Question 18 and 19. Considering our experiences, we don’t believe that we need to produce different products for patients with Androgenetic Alopecia and with AA.
- Brotzu, will the lotions be different according to the typology of Alopecia the patient is suffering from (Androgenetic Alopecia or AA) because of equol that will carry out its anti-dht action?
Question 18 and 19. Considering our experiences, we don’t believe that we need to produce different products for patients with Androgenetic Alopecia and with AA.
Good morning dr brotzu :
Questions 1, 2 and 3. The lotion is very effective in the initial stages of alopecia, for people who are younger than 30 years old. The results are great and hair loss is completely stopped. Hair growth is witnessed and also miniaturized hair or even vellus gain their normal appearance again.
Of course the treatment gives clear results after circa 30 days and it has to be carried out for many months.
For all alopecia its very effective i think now for all members its clear
- In your opinion what are the expectations an individual suffering from Androgenetic Alopecia should have towards your product?
- Do you think this product has the potential to eliminate the problem of Androgenetic Alopecia?
- Considering the trials you carried out and your opinion, to what extent can areas characterized by Androgenetic Alopecia, with miniaturized hair or even vellus, improved
Questions 1, 2 and 3. The lotion is very effective in the initial stages of alopecia, for people who are younger than 30 years old. The results are great and hair loss is completely stopped. Hair growth is witnessed and also miniaturized hair or even vellus gain their normal appearance again.
Of course the treatment gives clear results after circa 30 days and it has to be carried out for many months.
For all alopecia its very effective i think now for all members its clear
Détails and explications about mécanism from the BOSS !! Doctor brotzu
First of all, I want to clarify the mechanism of the lotion and its principles.
Alopecia (androgenetic, areata and totalis) is characterized by a bloodstream deficit of the blood vessels that reach the hair follicles providing them with oxygen and everything necessary for their metabolism and for hair growth.
The vessels are composed of a layer of endothelial cells that separate the tissues from the bloodstream. Endothelial cells are affected by many stimuli and some stimuli reduce bloodstream and stop their reproduction, thus reducing microcirculation.
Of course stimuli can be very different in the different types of alopecia but they all affect the microcirculation that supplies hair follicles.
Here is the capillary scheme:
The cell you observe in the foreground is called pericyte and it is responsible for regulating the bloodstream in the vessels. Minoxidil has an effect on it, by improving the blood stream in the vessel, but it doesn’t affect endothelial cells that on the other hand are affected by many simuli, such as infective stimuli, hormonal pathologies, etc.
Prostaglandin E1 (PGE1) affects both pericytes and endothelial cells fostering a vasodilation and their reproduction.
About 6 years ago we observed that some cationic liposomes that transported PGE1 were able to reduce androgenetic alopecia effects (due to unknown reasons no further research was carried out).
About 4 years ago we developed a lotion containing cationic liposomes that transported PGE1, S-equol and carnitine and we started testing it on people with androgenetic alopecia and on a later stage on a girl with alopecia areata. The results were great and unexpected.
PGE1 improved microcirculation, s-equol stopped 5-α-reductase thus preventing testosterone to turn into dihydrotestosterone and carnitine entered the beta oxidation of lipid chains improving their metabolism.
You can observe that each hair follicle has a blood vessel reaching it.
Since PGE1 is considered a drug we tried to substitute it with its biochemical precursor, that is dihomo-gamma-linolenic acid (DGLA). The results were the same and even better than the ones obtained with the lotions containing PGE1. There are several scientific publications stating that in cellular cultures DGLA stimulates the production of keratin. As a consequence, taking these observations into consideration, we started experimenting with a lotion containing DGLA instead of PGE1 on female individuals with androgenetic alopecia. The results were published in “Il Dermatologo” Year XXXVII ‘ N’ 1/2015 ‘ March, page 26.
Nowadays a trial is being carried out involving 60 people suffering from androgenetic alopecia and I am carrying out a trial on 18 people with alopecia totalis or areata.
enjoy !!
First of all, I want to clarify the mechanism of the lotion and its principles.
Alopecia (androgenetic, areata and totalis) is characterized by a bloodstream deficit of the blood vessels that reach the hair follicles providing them with oxygen and everything necessary for their metabolism and for hair growth.
The vessels are composed of a layer of endothelial cells that separate the tissues from the bloodstream. Endothelial cells are affected by many stimuli and some stimuli reduce bloodstream and stop their reproduction, thus reducing microcirculation.
Of course stimuli can be very different in the different types of alopecia but they all affect the microcirculation that supplies hair follicles.
Here is the capillary scheme:
The cell you observe in the foreground is called pericyte and it is responsible for regulating the bloodstream in the vessels. Minoxidil has an effect on it, by improving the blood stream in the vessel, but it doesn’t affect endothelial cells that on the other hand are affected by many simuli, such as infective stimuli, hormonal pathologies, etc.
Prostaglandin E1 (PGE1) affects both pericytes and endothelial cells fostering a vasodilation and their reproduction.
About 6 years ago we observed that some cationic liposomes that transported PGE1 were able to reduce androgenetic alopecia effects (due to unknown reasons no further research was carried out).
About 4 years ago we developed a lotion containing cationic liposomes that transported PGE1, S-equol and carnitine and we started testing it on people with androgenetic alopecia and on a later stage on a girl with alopecia areata. The results were great and unexpected.
PGE1 improved microcirculation, s-equol stopped 5-α-reductase thus preventing testosterone to turn into dihydrotestosterone and carnitine entered the beta oxidation of lipid chains improving their metabolism.
You can observe that each hair follicle has a blood vessel reaching it.
Since PGE1 is considered a drug we tried to substitute it with its biochemical precursor, that is dihomo-gamma-linolenic acid (DGLA). The results were the same and even better than the ones obtained with the lotions containing PGE1. There are several scientific publications stating that in cellular cultures DGLA stimulates the production of keratin. As a consequence, taking these observations into consideration, we started experimenting with a lotion containing DGLA instead of PGE1 on female individuals with androgenetic alopecia. The results were published in “Il Dermatologo” Year XXXVII ‘ N’ 1/2015 ‘ March, page 26.
Nowadays a trial is being carried out involving 60 people suffering from androgenetic alopecia and I am carrying out a trial on 18 people with alopecia totalis or areata.
enjoy !!
- Reaction score
- 907
i am really skeptical about the stuff , i wish so bad it could work , but THIS statement from the Doctor is characterized by a bloodstream deficit of the blood vessels that reach the hair follicles providing them with oxygen and everything necessary for their metabolism and for hair growth.
come on!
come on!
- Reaction score
- 1,403
you may want to try adding zinc sulfate to that as well. I mix zinc sulfate and b6 (p5p), and it has kept me from going bald for 12 years.
Im eager to use brotzu's lotion though, to encourage some regrowth.
FCKW36
Experienced Member
- Reaction score
- 622
At November 21st we won't get any information from Fidia. At this date Brotzu talks about AA and Brotzu has nothing to do with Fidia anymore because he sold the patent for using the lotion against Androgenetic Alopecia to Fidia.
And Manolo75 pls calm down you are spamming this thread way to hard.
And Manolo75 pls calm down you are spamming this thread way to hard.
@Manolo75 you're a paragon of enthusiasm, but you're not sharing any info we don't already know and there are some realities here:
1) Because Brotzu says isn't good enough, especially when he's made some dubious claims. In his defense, alopecia isn't his expertise, but I don't think that warrants a pass.
2) Any "evidence" thus far is purely anecdotal from internet forum posters.
3) For a page now, you've all conveniently dodged the point I brought up that it turns out DGLA is in fact very hard to get. This means that the one anecdote from those forums about manufacturer trouble is the only one supported by any sort of verifiable fact.
This is pertinent information, because as Brotzu said, the original mixture contained PGE1, which DGLA is a precursor to. No one would pick up the lotion when it used PGE1 because that would make it a drug and require the usual trials. FIDIA only picked it up because they see an opportunity to make a huge amount of money, very quickly. Make no mistake, they don't give a rat's *** about providing baldness treatment; it's all about the Benjamins, here.
DGLA is a vital ingredient and it is in short supply. Whether it works or not, if the lotion isn't viable as a product due to scarcity of a key component, they will drop this sh*t like an ugly baby.
1) Because Brotzu says isn't good enough, especially when he's made some dubious claims. In his defense, alopecia isn't his expertise, but I don't think that warrants a pass.
2) Any "evidence" thus far is purely anecdotal from internet forum posters.
3) For a page now, you've all conveniently dodged the point I brought up that it turns out DGLA is in fact very hard to get. This means that the one anecdote from those forums about manufacturer trouble is the only one supported by any sort of verifiable fact.
This is pertinent information, because as Brotzu said, the original mixture contained PGE1, which DGLA is a precursor to. No one would pick up the lotion when it used PGE1 because that would make it a drug and require the usual trials. FIDIA only picked it up because they see an opportunity to make a huge amount of money, very quickly. Make no mistake, they don't give a rat's *** about providing baldness treatment; it's all about the Benjamins, here.
DGLA is a vital ingredient and it is in short supply. Whether it works or not, if the lotion isn't viable as a product due to scarcity of a key component, they will drop this sh*t like an ugly baby.
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- 1,332
Does anyone have this paper?
- Reaction score
- 217
IT is hidden in this thread xd
I.D WALKER
Senior Member
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- 868
Worm,
What Norwood and/or male pattern baldness symptoms were you [experiencing] before you introduced aforesaid solution.
Is there a particular company you purchase yours from?
Much appreciated.
- Reaction score
- 117
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- 1,403
This is off topic, ill PM you instead. I was Norwood 1 diffuse - now 12 years having been very slowly losing, am still hanging onto a Norwood 2.
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https://www.scbt.com/scbt/product/dihomo-gamma-linolenic-acid-203-n-6-1783-84-2
DGLA - Dihomo-γ-linolenico (20: 3, n-6) (CAS 1783-84-2)
Price: $ 592 / G
DGLA in Brotzu lotion (Patent): 3,57 mg / 100 ml = 2,12 $
DGLA in Brotzu lotion (Il Dermatologo 03/2015) : 25 mg / 100 ml = 14,80 $
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