Kintor Pharmaceutical Announces AR-PROTAC (GT20029) Approved for Acne and Androgenic Alopecia Clinical Trials in China

[jake_b]

The AR is not responsible for keeping them dormant. Castration after the onset of balding halts its progression but does not reverse it. The PRLR might be responsible for keeping stem cells dormant. It would be a possible explanation for why hair loss usually happens around age 40 when testosterone declines and prolactin increases, although DHT stays the same and I don't know about scalp dht/prl.

I’ve seen so many people doing mtf hormone treatment go from nearly NW7 to full head of hair.

 

[pegasus2]

I’ve seen so many people doing mtf hormone treatment go from nearly NW7 to full head of hair.

Show me one who wasn't on estrogen

 

[FilthyFrancis]

Kintor Pharma top-up and block raise $182m

Kintor Pharmaceutical raised HK$1.17bn ($151m) on Wednesday from a top-up share placement, while a co-founder simultaneously trimmed his stake in the company.

www.globalcapital.com

Sorry for the paying article.

For those who did not see earlier this month:

AR antagonist developer Kintor set to raise up to $240M via HKEX IPO this month

BEIJING – Androgen receptor (AR)-related disease specialist Kintor Pharmaceutical Ltd., of Suzhou, China, is looking to raise up to HK$1.861 billion (US$240 million) in a Hong Kong IPO to advance its small-molecule AR antagonists, proxalutamide and pyrilutamide, both of which have first- and...

www.bioworld.com

 

[poopfeast420]

For pyrilutamide I assume they meant to say "advance to phase III", unless they mean the US

 

[nachos]

Any updates?

 

[Frenchboy]

The tests are gonna be really interesting.

Even if DHT and other androgens are responsible for sure of the hairloss, there are a LOT of other reasons that make our hair fall. Let’s see what happen if we « destroy » the androgens receptors!

Just afraid of the possible sides that It can give... Sounds super efficient but so dangerous in the same time.

 

[DuncanOP]

There is a estimated target day of market launch?
I have seen people saying to 2027, but I'm not sure