looking for perfect topical antiandrogen....again:(

[Newbaldy84]

we all know that flutagel has been discontinued which made some of us very unhappy. But now that I look back maybe that "stomach flu" I had was caused by flutagel when I felt like sh*t was vomiting had dirhea (spelling) and lost 5 pounds. It happened whe I started it applying to my head and beard in rather large amounts but I am not sure if it was caused by it because my dad had stomach flue around the same time so maybe not. Anyway I think flutamide is the best antiandrogen available today but it suck that they cant figure it out how to make it side effects free. Anyway I ust run out of my flutagel and right now I am holding on my 8 last pills of fincar. I have few idead but maybe you guys could help me.
Btw since I stopped flutagel on my beard it started to get thicker and thicker and I hate shaving again. so here goes. I c ould go back to the expensive fluridil which is big question mark and use this but This I could not apply to my beard. Another is wait for that new dutasteride topical from sinere but I think I'll pass cuz I hear bad storied about duta and how it destroys hairlines and I don't know if it would be as effective in reducing my beard as flutagel was. another think is get flutamide from genhair but use it like that. We know that if we put emu oil before it slows donw absorbation of another product. If we put it on top it help in absorbation. So I could just put emu oil before and than apply that flutamide from genhair? (what do you think about that idea)

C mon guys you have to help me. My hairline is constanty improving and it almost came back to the way it was before shedding.

Give me some good topical antiandrogen. I know topical flutamide works great but just like you I do value my life a little and wouldn't want to cuz any serious damage to my liver.

 

[squeegee]

Man!
Keep buyin Flutagel and stop to believe the hype and others :gay: on this forums....I am on it since a week and a half only and I can see a difference in the thickness of my hair...I started minoxidil also at the same time.. I am on Propecia 1 mg a day. This stuff is the sh*t! I got no side-effects at all...I put minoxidil after the shower and then wait until it is aborbed..Put the Flut on..No sides and big change in the feel and look of my hair already.. I tried internal dutasteride for 2 months and wasn't able to handle it at all.This drug is powerful because I started taking finasteride 5mg a day on empty stomach with no side effects at all and tried dutasteride 0.5 mg after 10 months on finasteride..Man My live was miserable for 2 months!.. I tried Topical dutasteride for few weeks before and I had no sides with dutasteride alone on my head..let see what with happen mixed with Flutagel and will try to keep it up until results and Sinere is coming with a Gel/dutasteride solution so....Even if I am on Flutagel right now I still need to retry Topical dutasteride on a long- term contract! Topical dutasteride will be the next big deal until then.. I am a loyal Flutagel buyer!

 

[el_duterino]

Hi squeegee, good to see you have success with Flutagel..this stuff is powerful indeed. Are you already seeing results of change of hair thickeness after a week and a half only ? sound pretty good.

As for SINERE, these guys have already removed it from the on-line ordering page..too bad.

Well we still have the MDF Solution from SAMSON Therapeutics

An advice about Flutagel (or flutamide)..the key is to put just a little on your hair, at the spots where it is really needed.

I spent one full day reading some research papers on flutamide and prostate cancer etc..and it seems that AR binding using androgen antagonists is dose related, meaning that only the same amount of DHT that would have been used to bind to the AR is needed as an antagonist (flutamide).
Some portion of the left over, un-used (un-binded) flutamide will end up systemically absorbed and you might get some sides after a while. Flutamide has more powerful (libido/tiredeness) sides than dutasteride.

So we don't need a lot of flutamide to get positive effects on the hair.

 

[zxAddict]

Flutamide always looked to risky to me. Fluridil looks too expensive and too new/untrialed. Anything with dutasteride or finasteride is a no-no (for me) so I'm left with copious amounts of spironolactone and Revivogen. And Super Zix II. And a bit of Tricomin. As far as DHT blocking/inhibiting goes that is. Am I missing something 'safe' in the topical DHT department?

 

[patagonia]

Man!
Keep buyin Flutagel and stop to believe the hype and others :gay: on this forums....I am on it since a week and a half only and I can see a difference in the thickness of my hair...I started minoxidil also at the same time.. I am on Propecia 1 mg a day. This stuff is the s***! I got no side-effects at all...I put minoxidil after the shower and then wait until it is aborbed..Put the Flut on..No sides and big change in the feel and look of my hair already.. I tried internal dutasteride for 2 months and wasn't able to handle it at all.This drug is powerful because I started taking finasteride 5mg a day on empty stomach with no side effects at all and tried dutasteride 0.5 mg after 10 months on finasteride..Man My live was miserable for 2 months!.. I tried Topical dutasteride for few weeks before and I had no sides with dutasteride alone on my head..let see what with happen mixed with Flutagel and will try to keep it up until results and Sinere is coming with a Gel/dutasteride solution so....Even if I am on Flutagel right now I still need to retry Topical dutasteride on a long- term contract! Topical dutasteride will be the next big deal until then.. I am a loyal Flutagel buyer!

Hey squeegee

good to see you are doing good with the flutagel! I also was very interested in it for the hairline..

The new dutasteride/egcg plus a regrowth agent in the new gel by Sinere looks very interesting.

How where you using topical dutasteride?

cheers man

 

[rusty_y2k2]

rumour has it the new topical will be some dutasteride, KGF, EGCG combination which could be very interesting if they have a way to keep the EGCG from oxidising (I'm guessing it'll be liposmal based).

Only concern for me is that dutasteride could be dragged systemic by any such liposomes, I'd actually be more interested in a topical just using EGCG and KGF.


Here's the quote

"Flutagel will be replaced by a new gel, which we consider as even more effective. It will contain Dutasteride or Finasteride along with a high amount of EGCG and maybe additional substances like KGF incorporated in special liposomes. Since we are not bound anymore to the specifications of the Sintov study, we can also make the gel much more liquid and we can skip the penetration enhancer glycerol oleate. It will be soon available so you won`t experience a major gap in your treatment."

 

[Bryan]

An advice about Flutagel (or flutamide)..the key is to put just a little on your hair, at the spots where it is really needed.

I spent one full day reading some research papers on flutamide and prostate cancer etc..and it seems that AR binding using androgen antagonists is dose related, meaning that only the same amount of DHT that would have been used to bind to the AR is needed as an antagonist (flutamide).
Some portion of the left over, un-used (un-binded) flutamide will end up systemically absorbed and you might get some sides after a while.

I've seen that idea suggested before, but the Chen et al study with topical flutamide appears to contradict it. They found no "local" effects at all, with any of the three separate doses that they tested (small, medium, or large).

 

[el_duterino]

Bryan,
-did "Chen et al " test rodents or humans ?
>rodents
-Do we have scientific proof that rodents hair reacts exactly like human hair ?
>no
-Did "Chen et al " used the same vehicle as the Sintov Study ?
>no
-Does Flutagel uses a gel based on the Sintov study ?
>yes
-It the vehicle designed to MAXIMIZE local effect ?
>yes
-Are my photos taken at week 3 fakes ?
>no
-Am I working for SINERE, GSK, Merck, Eucapil etc..or am I getting paid by them ?
>no..SINERE is not making flutagel anymore. I am neutral. In fact, I am not happy that SINERE stopped Flutagel.
If a treatment works for me I will share the news. Hairloss treatements are a hobby to me. Or call it an "obsession.."

-Is squeegee lying when he writes that he notices increased hair thickeness after only a week and a half ?
>no. he is a user who tries to beat hairloss like most of us here. no reasons to make it up.

-Is he noticing any side effects that would suggest major systemic absorbtion, which could explain such quick major results on his hair after only a week and a half ?
>no

Cheers
El Duterino

 

[Newbaldy84]

bryan I know that you are basing your opinion on studies but my beard started to thin out after application and ive been applying flutamide all over my scalp and my beard hasn't changed a bit. Once I started applying it to my beard baam! thinner wiskers I am not imaging suff this is for real which makes me think that maybe it does have local effect

 

[zxAddict]

bryan I know that you are basing your opinion on studies but my beard started to thin out after application and ive been applying flutamide all over my scalp and my beard hasn't changed a bit. Once I started applying it to my beard baam! thinner wiskers I am not imaging suff this is for real which makes me think that maybe it does have local effect

Applying to the beard seems like a good test of a product and your results are compelling, though I gotta say respectfully that slathering on a potentially harmful substance to make shaving easier is a strange practice. You must have one helluva strong beard. I hate shaving too, so I have a Norelco beard trimmer I keep on the shortest number one setting. Keeps me at a very short stubble which most chicks dig (though my girl likes it on the number three setting so thats where its stayed lately). No razor rash, no ingrown hairs, no expensive foam or blades to replace as the trimmer is still going strong 8 years later! Of course, if you need the clean shaven look for whatever reason then none of this is any help. :crazy:

 

[Newbaldy84]

yep my work requires me to be clean shaven. Even with a close shave I don't look clean the dark shadow persists. Flutagel was awesome. it reduced it greatly and give it more time it would make my beard so light that I wouldn't have to shave it next day cuz it wouldn't be visible. And now are back to being misreable again. there is no topical antiandrogen that's as effective as flutamide or is there?

 

[zxAddict]

Sounds like you'd be better off quitting your current job and auditioning for bit parts as a terrorist - TV demand is high.

But seriously, apart from RU and maybe fluridil, I'm not aware of anything else powerful or cosmetically acceptable (other than the old mainstays like spironolactone=funky skunky) which could do the trick. Though - as a terrorist smelling like a skunk may be a bonus.

 

[squeegee]

Man!
Keep buyin Flutagel and stop to believe the hype and others :gay: on this forums....I am on it since a week and a half only and I can see a difference in the thickness of my hair...I started minoxidil also at the same time.. I am on Propecia 1 mg a day. This stuff is the s***! I got no side-effects at all...I put minoxidil after the shower and then wait until it is aborbed..Put the Flut on..No sides and big change in the feel and look of my hair already.. I tried internal dutasteride for 2 months and wasn't able to handle it at all.This drug is powerful because I started taking finasteride 5mg a day on empty stomach with no side effects at all and tried dutasteride 0.5 mg after 10 months on finasteride..Man My live was miserable for 2 months!.. I tried Topical dutasteride for few weeks before and I had no sides with dutasteride alone on my head..let see what with happen mixed with Flutagel and will try to keep it up until results and Sinere is coming with a Gel/dutasteride solution so....Even if I am on Flutagel right now I still need to retry Topical dutasteride on a long- term contract! Topical dutasteride will be the next big deal until then.. I am a loyal Flutagel buyer!

Hey squeegee

good to see you are doing good with the flutagel! I also was very interested in it for the hairline..

The new dutasteride/egcg plus a regrowth agent in the new gel by Sinere looks very interesting.

How where you using topical dutasteride?

cheers man

I was mixing my Dutasteride with Nioxin Scalp treatment: PROPYLENE GLYCOL mix...and then switch with Aloe Vera..by the time I was havin bad sides effects from Oral dutasteride that I was taking at the same time...Eyes like a raccoon..feel like sh*t all day.. I was sturborn and was trying to much stuff at the same time...The only good thing about trying it for 2 months is I had blond hairs all over my temples and the front area of my scalp..but the sides just stop me of being a guina pig of the drug.....I wasn't able to have sex with my gf because I was farting all the times on that lol!! I started to grow a belly too......I just gonna buy some more and rub it on my head directly and go with minoxidil after that. The idea of mixing it with my left over Flutagel is still there.. Will see.. I just want to try something and keep it like that for months and stop trying all kind of experimentations at the same time! We all want a quick fix! I just wrote an e-mail to Sinere inquiring why they stopped selling Flut and when the Dutagel will be available....I like this company so far..They always trying to come up with new sh*t...I like to rub Flut in my hair! Almost 2 weeks and I know that something is happening to my hair already....but I started it with minoxidil mixed with Finasteride at the same time...Flut is sticky as hell! I can spike my hair with it!

 

[zxAddict]

Man!
Keep buyin Flutagel and stop to believe the hype and others :gay: on this forums....I am on it since a week and a half only and I can see a difference in the thickness of my hair...

Man, theres no way. A week?

 

[Guest]

Why dont you keep using flutagel then you moron?

 

[rusty_y2k2]

Why dont you keep using flutagel then you moron?

just a guess, but proooobably because it's been discontinued...... reading is an art form.

 

[Bryan]

Bryan,
-did "Chen et al " test rodents or humans ?
>rodents

Do you think a good enough way to answer my objection is just to cite the simple fact that rodents are different from humans?

-Do we have scientific proof that rodents hair reacts exactly like human hair ?
>no

And what is it about rodent hair that would refute my objection?

-Did "Chen et al " used the same vehicle as the Sintov Study ?
>no
-Does Flutagel uses a gel based on the Sintov study ?
>yes
-It the vehicle designed to MAXIMIZE local effect ?
>yes

How does the Sintov vehicle supposedly "maximize" local effects?

-Are my photos taken at week 3 fakes ?
>no

-How many people really believe that you can tell the difference in your hair based only on a (presumably) small increase in thickness in the first short length of each hair (less than half an inch) closest to the root?
>Probably nobody!

 

[Guest]

Why dont you keep using flutagel then you moron?

just a guess, but proooobably because it's been discontinued...... reading is an art form.

reading is an artform? Were you trying to make a smart and funny statement? Because it was neither you tool :shakehead:

 

[patagonia]

Man!
Keep buyin Flutagel and stop to believe the hype and others :gay: on this forums....I am on it since a week and a half only and I can see a difference in the thickness of my hair...I started minoxidil also at the same time.. I am on Propecia 1 mg a day. This stuff is the s***! I got no side-effects at all...I put minoxidil after the shower and then wait until it is aborbed..Put the Flut on..No sides and big change in the feel and look of my hair already.. I tried internal dutasteride for 2 months and wasn't able to handle it at all.This drug is powerful because I started taking finasteride 5mg a day on empty stomach with no side effects at all and tried dutasteride 0.5 mg after 10 months on finasteride..Man My live was miserable for 2 months!.. I tried Topical dutasteride for few weeks before and I had no sides with dutasteride alone on my head..let see what with happen mixed with Flutagel and will try to keep it up until results and Sinere is coming with a Gel/dutasteride solution so....Even if I am on Flutagel right now I still need to retry Topical dutasteride on a long- term contract! Topical dutasteride will be the next big deal until then.. I am a loyal Flutagel buyer!

Hey squeegee

good to see you are doing good with the flutagel! I also was very interested in it for the hairline..

The new dutasteride/egcg plus a regrowth agent in the new gel by Sinere looks very interesting.

How where you using topical dutasteride?

cheers man

I was mixing my Dutasteride with Nioxin Scalp treatment: PROPYLENE GLYCOL mix...and then switch with Aloe Vera..by the time I was havin bad sides effects from Oral dutasteride that I was taking at the same time...Eyes like a raccoon..feel like s*** all day.. I was sturborn and was trying to much stuff at the same time...The only good thing about trying it for 2 months is I had blond hairs all over my temples and the front area of my scalp..but the sides just stop me of being a guina pig of the drug.....I wasn't able to have sex with my gf because I was farting all the times on that lol!! I started to grow a belly too......I just gonna buy some more and rub it on my head directly and go with minoxidil after that. The idea of mixing it with my left over Flutagel is still there.. Will see.. I just want to try something and keep it like that for months and stop trying all kind of experimentations at the same time! We all want a quick fix! I just wrote an e-mail to Sinere inquiring why they stopped selling Flut and when the Dutagel will be available....I like this company so far..They always trying to come up with new s***...I like to rub Flut in my hair! Almost 2 weeks and I know that something is happening to my hair already....but I started it with minoxidil mixed with Finasteride at the same time...Flut is sticky as hell! I can spike my hair with it!

squeegee,

looks like you are using a good number of things, your gutsy!
I agree, Sinere is a company that is trying to put out new stuff. I admire the effort.

That minoxidil with a little finasteride and maybe tretinoin looks mighty good on a study I saw.. hope it gives you good results man.
I believe the key is to find a good regimen you can handle and stick with it for the long run.

I bet your girlfriend´s glad the wind music stopped...lol!

good luck and keep us posted

 

[rusty_y2k2]

Newbaldy - if you do end up trying their new topical when it comes out, be sure to keep us all updated. I'm quite interested in that one... good luck whatever way you end up going!


Davidoff - From the majority of your posts you seem like a very angry little chappy. Go get a hug or something.