Looking To Start Finasteride - Few Questions

[TomRiddle]

And you would take 0.25 a day - why doesn't everyone do this ?
Sorry about all the questions just intrigued.

Well mate, people are dumb and trust doctors blindly, regardless of what the truth is... Even the aussie doctors from youtube are saying that it's just a marketing scheme, it's all about the money, why make 0.25 pills when you can make 1mg and charge more money for it, why tell people that it actually sticks into the tissue for weeks and maybe months and why tell people that DHT is building up in 3 days after the first pill when you can make them ingest everyday one so they could pay more, regardless of this making the chances of getting sides bigger...

They want the money and they just don't give a f*** of what happens after, you can't do sh*t about it anyways, who are you, a depressed dude that is losing his hair and takes their medicine? They are big pharma with billion of dollars yearly, what could you possible do? Did you say you have side effects from their pill? No, it's in your head, you were already depressed because of your hairloss and you triggered a placebo effect that may never go away lol...

But sticking to the subject, i personally think that as long as even their studies show that it's the same effectiveness at doses after 0.2 than what can i say, on my behalf anybody who takes more is just an misinformed idiot, like most are so what's more to say than that...

 

[josefhair]

Okay so 0.25 everyday would be sufficient

 

[josefhair]

So essentially you can make a month last for 4 months give or take?
Do you have to take everyday? because have seen people who take 5/7 days a week?

 

[TomRiddle]

My opinion is that you could take it at least at a maximum of 3 days, maybe it's better to just take it Monday, Wednesday and Friday and have the weekend off, or maybe just Wednesday and Saturday and just that, but i would not let more than 3 days between the dosages, they say that it takes 3 days for your DHT to return to normal serum levels and i would not let my hormones fluctuate to much, the pill already unbalances your hormones...

 

[Hairicane]

Hi all

I’m 27 and I’ve been experiencing shedding for almost a year now. Hairline fairly OK still but crown definitely thinning. So I think it’s time to give finasteride a go.

The only potential side effect that worries me is the link to depression, I couldn’t find much information on studies or how common it is. Can anyone on here provide any more info? My libido is high as it is so I don’t mind if that drops a little.

Also, I am looking to start off on a dose of 0.25mg every other day. Will the broken segments of the pill go off or go bad over that timeframe?

I’m based in the UK and would appreciate any help on this.

Many thanks.

If you cut a pill into quarters, then the last piece will be taken 7 days later, assuming you store the cut parts in a cool and dry location out of sunlight then they should be fine. Any longer and I'd begin to worry. Sounds like a good plan, if you have no sides but no results after a while you can always up your dose.

Good luck.

 

[Haironnu]

And you would take 0.25 a day - why doesn't everyone do this ?
Sorry about all the questions just intrigued.

there is a reason for taking 1mg instead of 0.25mg, something about a % of people that 0.25mg affects them not as good as 1mg, so the company issued 1mg as the recommended dosage since 1mg will "cover" all of the people, or something like that.

@pegasus2 can explain it better, if he feels like it

 

[WaccWaccWacc]

Yeah but can do no harm to get it checked and this way you'll know your hormone levels pre treatment.

The only thing I have to say about this is if youre starting young i.e 19-22 your hormones aren’t even “normal” to begin with hence all the acne and what not. Definitely a good, no harm, index of a lot of them but definitely off for a few.

 

[WaccWaccWacc]

And you would take 0.25 a day - why doesn't everyone do this ?
Sorry about all the questions just intrigued.

It’s inconvenient to cut pills and adds a factor of misuse. If you start cutting your pills to .25mg, dont get sides, but still lose just as much hair - you will question if you’re cutting technique/storage is adequate.

Thats why I personally think one should start with 1mg. No sides - continue use as normal. If sides, lower dosage.

 

[shotta287]

Thanks all some good information. I know the depression side effect can be hard to quantify properly but can anyone point out some studies/trials that have been done linking depression to finasteride?

 

[HDeJong]

Thanks all some good information. I know the depression side effect can be hard to quantify properly but can anyone point out some studies/trials that have been done linking depression to finasteride?

I personally dont believe in depression from finasteride. I think its more in your head. People who take finasteride are mostly insecure about their hair and you hear a lot of people saying they got depressed by their hairloss. Im not a doctor of any kind so.. Its just my opinion.

 

[TomRiddle]

I personally dont believe in depression from finasteride. I think its more in your head. People who take finasteride are mostly insecure about their hair and you hear a lot of people saying they got depressed by their hairloss. Im not a doctor of any kind so.. Its just my opinion.

Just lol....

The Dark Side of 5α-Reductase Inhibitors' Therapy: Sexual Dysfunction, High Gleason Grade Prostate Cancer and Depression

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064044/

 

[JohnSmith21]

Don’t listen to that pigeon guy or 99% of the ocd weirdos on this forum. if your losing hair try finasteride. 1% of people get sides, and if you DO get sides, they go away when u stop. i’ve been a natural bodybuilder for awhile. i started receding so i took finasteride. been on it for a year, zero side effects, kept all the hair i’ve had. sex drive still high, no change in weight lifting or facial hair. ONLY side i have is thinner body hair. that’s it.

 

[TomRiddle]

Don’t listen to that pigeon guy or 99% of the ocd weirdos on this forum. if your losing hair try finasteride. 1% of people get sides, and if you DO get sides, they go away when u stop. i’ve been a natural bodybuilder for awhile. i started receding so i took finasteride. been on it for a year, zero side effects, kept all the hair i’ve had. sex drive still high, no change in weight lifting or facial hair. ONLY side i have is thinner body hair. that’s it.

1% lmao, what an idiot. So let me get this straight, if your experience until now is good with finasteride that means that everybody's experience will be the same correct? Let's just all ignore all the others people who report sides and all the other scientific material that tells us something different and let's just trust the complete stranger from a hair loss forum, he must be right... Just lol, this forum is full of tards

Here is your 1% and let's see you in a few years how your hanging, or let's say, how your dick will be hanging lol...

Adverse Event Reporting in Clinical Trials of Finasteride for Androgenic Alopecia: A Meta-analysis

Abstract
Importance: Two meta-analyses conclude that finasteride treatment of androgenic alopecia (Androgenetic Alopecia) is safe but do not assess quality of safety reporting.

Objective: To assess safety reporting for clinical trial reports of finasteride for Androgenetic Alopecia.

Data sources: MEDLINE, ClinicalTrials.gov, and a clinical data repository for an academic medical center.

Study selection: Published clinical trial reports for finasteride treatment of Androgenetic Alopecia.

Data extraction and synthesis: For each trial, we assessed quality of adverse event reporting, extracted the number and type of adverse events in treatment and placebo groups, and assessed duration of safety evaluation and adequacy of blinding. Two observers independently extracted the data; differences were resolved by consensus. We assessed generalizability in a large cohort of men prescribed finasteride, 1.25 mg/d or less, by assessing for eligibility in the finasteride-Androgenetic Alopecia pivotal trials.

Main outcomes and measures: Quality was assessed as adequate, partially adequate, inadequate, or no events reported. We used funnel plots of the hazard ratio to assess bias.

Results: Of 34 clinical trials, none had adequate safety reporting, 19 were partially adequate, 12 were inadequate, and 3 reported no adverse events. Funnel plots were asymmetric with a bias toward lower odds ratio for sexual adverse effects, suggesting systematic underdetection. No reports assessed adequacy of blinding, 18 (53%) disclosed conflicts of interest, and 19 (56%) received funding from the manufacturer. Duration of drug safety evaluation was 1 year or less for 26 of 34 trials (76%). Of 5704 men in the clinical data repository who were treated for Androgenetic Alopecia with finasteride, 1.25 mg/d or less, for Androgenetic Alopecia, only 31% met inclusion criteria for the pivotal trials referenced in the manufacturer's full prescribing information and 33% took finasteride for more than 1 year.

Conclusions and relevance: Available toxicity information from clinical trials of finasteride in men with Androgenetic Alopecia is very limited, is of poor quality, and seems to be systematically biased. In a cohort of men prescribed finasteride for routine treatment of Androgenetic Alopecia, most would have been excluded from the pivotal studies that supported US Food and Drug Administration approval for Androgenetic Alopecia. Published reports of clinical trials provide insufficient information to establish the safety profile for finasteride in the treatment of Androgenetic Alopecia.

https://pubmed.ncbi.nlm.nih.gov/25830296/