Lowering finasteride dosage?

Cincinnati Kid

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Just out of curiousity, has anyone who experienced side effects while taking 1-1.25mg daily finasteride seen those effects lessened with a smaller dosage of say .5 to .625 daily? My side effects really only consist of watery semen and lack of morning wood, but I'm curious if lowering my dosage to .625, since it was pointed out to me that amount could still effectively block DHT, would be able to lessen said side effects because I've been on finasteride for 3 months now, and I still haven't returned to baseline. Maybe it just takes longer for some people, or perhaps a lowered dose would help with that?
 

zzzzz

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lowering dose wont help with sides serum DHT inhibition is pretty much exactly the same regardless of dose so sides wont be any better
 

Ventures

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Everybody reacts differently . You might lessen sides if you lower your dose to 0.5 mg, but in that case you also inhibit smaller percentage of DHT. So, If you do not experience sides on lower doses it is probably because lower doses inhibit less DHT. You can't have it both, same level of DHT suppression and don't get sides.

Sides and their intensity are in direct connection to the suppressed DHT level.
 

Cincinnati Kid

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Thanks guys, you're pretty much echoing what I already thought was the answer to my question. My sides aren't THAT bad to the point where I'm going to consider going off the finasteride. Erection quality is still good, and let's face it, that's the most important thing. I just was hoping I could get back to normal sooner rather than later. I just gave myself another buzzcut (number 4) today and it's a lot easier to see that the big 3 are really starting to give me some solid regrowth and coverage in the crown. Gotta take the bad with the good.
 

Donny J

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why not lower your dose and see if it actually does get rid of your sides? knowing that the positive effects should be the same at a lowered dose, you don't have much to lose... and keep us posted!
 

zzzzz

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wtf guys. lowering your dose has been shown to do almost nothing to serum dht inhibition. LOWERING DOSE WILL NOT CHANGE YOUR SIDES OR DHT SUPPRESSION

like for real I negged both u guys for making totally uninformed posts
 

Donny J

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wtf guys. lowering your dose has been shown to do almost nothing to serum dht inhibition. LOWERING DOSE WILL NOT CHANGE YOUR SIDES OR DHT SUPPRESSION

like for real I negged both u guys for making totally uninformed posts
like for real everybody's body reacts differently to drugs. this is why some people receive sides and others don't. so, like i said, he won't know for certain unless he tries it himself.

negged for being so damn jumpy.
 

xRedStaRx

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wtf guys. lowering your dose has been shown to do almost nothing to serum dht inhibition. LOWERING DOSE WILL NOT CHANGE YOUR SIDES OR DHT SUPPRESSION

like for real I negged both u guys for making totally uninformed posts

Almost nothing said in this thread is scientifically true, nor relevant. Including yours.

Serum DHT =/= DHT inhibition.
 

zzzzz

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The level of DHT inhibition is the cause of serum DHT levels, Low serum DHT levels cause sides. WTF is Serum DHT =/= DHT inhibition mean I know the ****ing difference

You guys are morons, .25mg inhibits the same amount as 1mg pretty much, it is not different for everyone. Serum DHT will be the same whether you are taking .25mg or 1mg and therefore your sides will be the exact same. He can be certain without trying it because it has been shown that both doses inhibit the same ammount
 

xRedStaRx

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The level of DHT inhibition is the cause of serum DHT levels, Low serum DHT levels cause sides. WTF is Serum DHT =/= DHT inhibition mean I know the ****ing difference

You guys are morons, .25mg inhibits the same amount as 1mg pretty much, it is not different for everyone. Serum DHT will be the same whether you are taking .25mg or 1mg and therefore your sides will be the exact same. He can be certain without trying it because it has been shown that both doses inhibit the same ammount

Yes, serum DHT levels is a proxy for DHT inhibition, but it's just, A PROXY.

Serum DHT does not mean anything in terms of hair loss. The amount of serum DHT inhibition by different doses of finasteride is a rough ancillary at best.

BUT, with that said, there doesn't seem to be a huge difference either way beyond the plateau level of the serum DHT dose-response curve, in terms of tissue concentration.
 

brandnew88

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I have tried propecia at 1mg, .5 and .25 got side after a few days. This time I tried at .25 every 3rd day then moved to .25 eod then to .33 every other day. It's been 4.5 months and today I took my first half of a pill. Everything's been working fine. I think some people just have to give their body time to adjust and ride the sides out or start with very low doses.
 

zzzzz

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I have tried propecia at 1mg, .5 and .25 got side after a few days. This time I tried at .25 every 3rd day then moved to .25 eod then to .33 every other day. It's been 4.5 months and today I took my first half of a pill. Everything's been working fine. I think some people just have to give their body time to adjust and ride the sides out or start with very low doses.

Sides get better over time anyway, even if you stay at the same dose. There is so much variance and combined with placebo effect any anecdotal evidence is useless
 

cthulhu2.0

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propecia-dht-inhibition-curve.jpg
As you can see from this finasteride clinical trial, you would have to really get a low dose going to lessen the inhibition of dht; and we are talking .2mg and below. It would be a lot easier to take finasteride every other day or every other other day.
 

Cincinnati Kid

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Update:
Been on .625mg finasteride daily, as opposed to 1.25mg, for two weeks now, and I can say that sides have had less of an effect of late. They're still noticeable, but not nearly as bad as before. I'm probably at about 85% erection now as opposed to about 50-60% tops coupled with intermittent loss of desire a few weeks ago. Katy Perry could have called me for an emergency titty f*ck and I wouldn't have been able to oblige because it got that bad at times. I get occasional semi morning wood, which I never thought I would miss, but it's like seeing an old friend after an extended absence and you just want to hug it out because you missed them. Semen quality is slightly better, but still pretty low viscosity overall. Anyway, I don't know if all of this is because of the lowered dosage, my body has adjusted to the presence of finasteride now that I am past the 3 month mark, or some combination of the two. I'm just happy to report that I'm getting some of my old body function back to go along with some DHT inhibition, and I'm not ready to jump off the wagon and quit like I was a couple weeks ago.
 

xRedStaRx

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Update:
Been on .625mg finasteride daily, as opposed to 1.25mg, for two weeks now, and I can say that sides have had less of an effect of late. They're still noticeable, but not nearly as bad as before. I'm probably at about 85% erection now as opposed to about 50-60% tops coupled with intermittent loss of desire a few weeks ago. Katy Perry could have called me for an emergency titty f*ck and I wouldn't have been able to oblige because it got that bad at times. I get occasional semi morning wood, which I never thought I would miss, but it's like seeing an old friend after an extended absence and you just want to hug it out because you missed them. Semen quality is slightly better, but still pretty low viscosity overall. Anyway, I don't know if all of this is because of the lowered dosage, my body has adjusted to the presence of finasteride now that I am past the 3 month mark, or some combination of the two. I'm just happy to report that I'm getting some of my old body function back to go along with some DHT inhibition, and I'm not ready to jump off the wagon and quit like I was a couple weeks ago.

Keep up with the morning wood progress, as this should be the best indicator of sexual problems.
 
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