Newly Discovered Factor in Androgenetic Alopecia. The Cure is Near?

2020

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Re: A recently discovered new factor in AA, the cure is near :)

which foods? Gluten?

anyways, I have absolutely no allergies or any health problems whatsoever so I don't know what to think....
Is it possible that baldness is not really genetic, it's just that you have some underlying allergies which makes your scalp produce excessive prostaglandins and make you lose hair? :dunno: :dunno: :dunno:
 

Boldy

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Re: A recently discovered new factor in AA, the cure is near :)

I have allergy for spicy food etc..

Well, It should be genetic. Because its triggert BY androgens. and just some parts of the body like the scalp Produce excessive Prostaglandines..

I cant wait to see if this theory really works.

Then we all together could say bye bye to the depression comes from hairloss!!

Maybe you should change your name to 2012 ;) haha




2020 said:
which foods? Gluten?

anyways, I have absolutely no allergies or any health problems whatsoever so I don't know what to think....
Is it possible that baldness is not really genetic, it's just that you have some underlying allergies which makes your scalp produce excessive prostaglandins and make you lose hair? :dunno: :dunno: :dunno:
 

young trunks

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Re: A recently discovered new factor in AA, the cure is near :)

Boldy said:
Awsome!

http://www.arthritistoday.org/nutrition ... mation.php


this makes sense, But the downside it will REDUCE PGF2a+PG2E also!!+COX1

I guess its good to give it a try intill the production of OC000459 finishes.


Could you past me the links?, I would like to read more about these people on the forums. Quite interesting!:)

young trunks said:
guys...I found a cheaper treatment that I'm starting.

TREATMENT: Massage any pure, natural oil into scalp, Extra virgin olive, coconut and grape seed work well. Then brush vigorously preferably using a palm held brush with short natural boar bristles.(Quite stiff bristles are best). You can see them on Amazon - they are known as military brushes.
Brush strongly so you feel it stimulating/irritating scalp. But do not overdo it. Do 90 /110 strokes each day and focus on where loss is. You may be apprehensive about irritating scalp - believe me I was too but this is what will force new growth as it unplugs the blocked hair ducts that result in loss - they are experienced as the painful small itching spots.
As you brush some shedding and breakage may occur at first but will quickly stop as brushing makes hair better anchored and stronger. New hairs will appear and will be weak looking and sparse. Keep up the brushing and do not be concerned if brushing uproots them, as they will RE-APPEAR EVEN STRONGER and will not be uprooted.
I found it best at the beginning to apply the oil at night, do the brushing and sleep with it that way and wash off in the morning.

It work for this guy and it's the cheapest treatment. Alot of people are having success on another forum too.

No problem man.. I even joined the forum after reading through it. The idea came from an ad in an unpopular magazine in the 80s (the kinds you see at grocery stores)...it said no pills, no topicals, etc.. Some dude tried it and it worked. Then this one guy did it his whole life and it worked he lived to late 80s.

Anyway here is the link:

http://immortalhair.forumandco.com/t724 ... illa-power
 

young trunks

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Re: A recently discovered new factor in AA, the cure is near :)

young trunks said:
Boldy said:
Awsome!

http://www.arthritistoday.org/nutrition ... mation.php


this makes sense, But the downside it will REDUCE PGF2a+PG2E also!!+COX1

I guess its good to give it a try intill the production of OC000459 finishes.


Could you past me the links?, I would like to read more about these people on the forums. Quite interesting!:)

[quote="young trunks":3csonoeu]guys...I found a cheaper treatment that I'm starting.

TREATMENT: Massage any pure, natural oil into scalp, Extra virgin olive, coconut and grape seed work well. Then brush vigorously preferably using a palm held brush with short natural boar bristles.(Quite stiff bristles are best). You can see them on Amazon - they are known as military brushes.
Brush strongly so you feel it stimulating/irritating scalp. But do not overdo it. Do 90 /110 strokes each day and focus on where loss is. You may be apprehensive about irritating scalp - believe me I was too but this is what will force new growth as it unplugs the blocked hair ducts that result in loss - they are experienced as the painful small itching spots.
As you brush some shedding and breakage may occur at first but will quickly stop as brushing makes hair better anchored and stronger. New hairs will appear and will be weak looking and sparse. Keep up the brushing and do not be concerned if brushing uproots them, as they will RE-APPEAR EVEN STRONGER and will not be uprooted.
I found it best at the beginning to apply the oil at night, do the brushing and sleep with it that way and wash off in the morning.

It work for this guy and it's the cheapest treatment. Alot of people are having success on another forum too.
[/quote:3csonoeu]

No problem man.. I even joined the forum after reading through it. The idea came from an ad in an unpopular magazine in the 80s (the kinds you see at grocery stores)...it said no pills, no topicals, etc.. Some dude tried it and it worked. Then this one guy did it his whole life and it worked he lived to late 80s.

WTF why isn't link working...just google this : (The original Papilla Power??) and it's the first link that appears with that in it.
 

2020

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Re: A recently discovered new factor in AA, the cure is near :)

oh come on.... take this crap to immortal hair forums. First of all: WHY WOULD IT WORK?? do you know how many "oils" have been proposed to treat male pattern baldness? What makes this one any different??
 

Boldy

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Re: A recently discovered new factor in AA, the cure is near :)

2020 said:
oh come on.... take this crap to immortal hair forums. First of all: WHY WOULD IT WORK?? do you know how many "oils" have been proposed to treat male pattern baldness? What makes this one any different??

2020, It could work at couple %, but as you and I know, inhibition couple % of COX2 is not effective enough. There will still be much PGD2 left. But its could be a nice try to slow the process down for some people :).
And they will deal with reduced PG2E+PGF2a.. so thi natural treatment will have its downsides.

to completely stop PGD2 attacking, we must block the CRTH2 receptor :)


I cant wait for My OC000459. If the theory and study is 100% right. I will be the happiest man on earth! :innocent: :)
 

waynakyo

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Re: A recently discovered new factor in AA, the cure is near :)

Boldy are you planning to check purity before you try it ?
 

Boldy

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Re: A recently discovered new factor in AA, the cure is near :)

waynakyo said:
Boldy are you planning to check purity before you try it ?


ON Hairloss help, Me and others are planning to check the purity. and we might ask Hairy for that. so yess we will set something up Just to be sure.

Although, I trust the lab, so once they finish production, and they show me the HNMR+HPLC+Mass Spec, I will order and start using it. And let the supplier send hairy a test sample, so we know for sure its OC000459 99% pure.

My hairline is getting very bad, So i cant spill any more time. thats why I´m going to order before we get hairy´s results.
 

2020

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Re: A recently discovered new factor in AA, the cure is near :)

what about the fact that 18 or so proteins were in excess in bald scalps? PGD2 was one of them, but what makes you think it's THE ONLY ONE responsible for hair loss? It may be responsible for inflammation but that may be it.
How much of PGD2 did they inject into mice? If it's 1000x normal levels then yeah, I guess it would make your hair fall out. What if they tried injecting 12x?
 

Boldy

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Re: A recently discovered new factor in AA, the cure is near :)

2020 said:
what about the fact that 18 or so proteins were in excess in bald scalps? PGD2 was one of them, but what makes you think it's THE ONLY ONE responsible for hair loss? It may be responsible for inflammation but that may be it.
How much of PGD2 did they inject into mice? If it's 1000x normal levels then yeah, I guess it would make your hair fall out. What if they tried injecting 12x?


Time will tell.

Its a chain reaction. More androgens= more cox and all its derivates.

PGD2 was most increased of all of them.



this still an experiment. We all hope the study is right offcourse.
 

TheLastHairbender

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Re: A recently discovered new factor in AA, the cure is near :)

Boldy said:
More androgens= more cox

That works the other way around too.
 

Boldy

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Re: A recently discovered new factor in AA, the cure is near :)

TheLastHairbender said:
Boldy said:
More androgens= more cox

That works the other way around too.


In our Androgenetic Alopecia scalp, cox increases when androgens increase.
 

TheLastHairbender

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Re: A recently discovered new factor in AA, the cure is near :)

Ya missed it:

More c**** in a room -> more androgens
 

Boldy

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Re: A recently discovered new factor in AA, the cure is near :)

TheLastHairbender said:
Ya missed it:

More c**** in a room -> more androgens


hahah, very funny :p
 

yassin

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Re: A recently discovered new factor in AA, the cure is near :)

I think that PGD2 maybe a by-product in the pathogenesis of AA. it's suppression may not treat the AA. i think every body here must not treat himself as a lab rabbit and just wait and use the only the proven medications
 

2020

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Re: A recently discovered new factor in AA, the cure is near :)

yassin said:
I think that PGD2 maybe a by-product in the pathogenesis of AA. it's suppression may not treat the AA. i think every body here must not treat himself as a lab rabbit and just wait and use the only the proven medications

are you talking about Alopecia Areata???

if not: why wouldn't it work for baldness?? It's been shown that this protein DIRECTLY shrinks follicles... explain yourself
 

sapinho

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Re: A recently discovered new factor in AA, the cure is near :)

I had no idea what a Niacin (Vit. B-3) flush was, never experienced it, but it appears to be somewhat of a health fad. The capillaries are dilated and gives a warm, sometimes burning(!)/itchy, feeling throughout the skin.

Whether or not it's healthy, I don't know, but apparently a lot of PGD2 is released as part of the process and most people feel fine after a few minutes.

I wonder if applying this topically would use up a lot of the PGD2 synthase. Assuming(!) the PGD2 is flushed out somehow, this might actually reduce the amount of PGD2 the body can produce for the remainder of the day and actually lower PGD2 levels.

Mechanically scratched mice were shown to have lowered COX1 and PGD2 levels, suggesting that it is possible to saturate PGD2 through something as simple as scratching. So, perhaps Niacin could quickly saturate and do the same? Again, all of this on the flimsy assumption that we can also flush out the PGD2 produced during the so-called flushing.
 

rwGourmetStyleWellness

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Re: A recently discovered new factor in AA, the cure is near :)

Hmmm.

I've read that aspirin reduces COX-2. I wonder will that translate in less hair shed. You know, aspirin may be an anti inflammatory.
 

zeroes

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Re: A recently discovered new factor in AA, the cure is near :)

sapinho said:
I had no idea what a Niacin (Vit. B-3) flush was, never experienced it, but it appears to be somewhat of a health fad. The capillaries are dilated and gives a warm, sometimes burning(!)/itchy, feeling throughout the skin.

I took a very low dosage of 1 x 100mg capsule the other night and I personally didn't enjoy the experience. Until it's proven to be beneficial I am going to stay away from it.
 

czvezda

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Re: A recently discovered new factor in AA, the cure is near :)

rwGourmetStyleWellness said:
Hmmm.

I've read that aspirin reduces COX-2. I wonder will that translate in less hair shed. You know, aspirin may be an anti inflammatory.

This is the quote from PGD2 study:
This model predicts then that efforts to reverse alopecia should optimally focus on both enhancing PGE2 and inhibiting PGD2 signaling. This model also explains why agents such as aspirin, which inhibit upstream prostaglandin synthesis enzymes
(PTGS1 and PTGS2), have minimal effects on hair growth because of likely equally decreased production of PGE2 and PGD2.
 
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