Newly Discovered Factor in Androgenetic Alopecia. The Cure is Near?

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bornthisway

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What happened to all the cetirizine users? I read on HS that the users experiencing results were dissolving 33 tablets in 50 ml water before adding ethanol and propylene glycol. Don't recall how many tablets were being used here, believe it was a much smaller quantity.
 
baldnesssadness

baldnesssadness

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honestly hard to say really. but i started with minoxidil together with cetirizine and i can tell you this it has been only some days and i get this vellus hair much lower than my hairline. When i was a kid i had really strong hair and clearly a norwood zero ,if the vellus hair grew to be normal hair i believe it would be the same hairline i had as a kid. what squeegee says is true ive been to asian like phillipphines, south korea and hong kong its really hard 2 find a bald person the reason has to be diet the western diet allmost consists of omega 6. Those countries i been through the diet is much different than the western. which boost their hair , i guess this is why native americans dont go bald too.. it all ****ing makes sense now... and thank you squeegee for showing facts this pgd2 has to be it , this i believe is because the realition it had with testosterone ... has anyone by the way used Miconazole Nitrate? and can i used together with minoxidil? (SORRY for my not so good english)
 
Sparky4444

Sparky4444

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sure, there may be an enhanced sensitivity to things in the western, European and near-East diets..but this evolved over centuries, if not a thousands of years...but changing diets won't help now...the fix is in and those little bastard follicles are prone to DHT -- once DHT does the damage, you need more than to eliminate DHT to get those follicles to return to normal function....
 
baldnesssadness

baldnesssadness

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i dont believe dht is the perfect cause or the sollution for baldness...
because many men regarding do dht levels high or low still mantain their hair because i had a friend which used finasterid and he regrew the hair on his crown but the temples still receeded even after year of use then later it stopped in a place and stayed there ... correct me if im wrong but isnt the theory this?
dht-->cox-->pgd2--->male pattern baldness
maybe blocking pgd2 will stop hair loss but we need pge to grow hair dht is unrelevant and the reason it works is because reducing dht also reduces pgd2. thanks to squeegee we found that out now , i dont know where he finds this stuff but thank god for you , the most usefull poster ... what happend to boldy?
 
Sparky4444

Sparky4444

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baldnesssadness said:
i dont believe dht is the perfect cause or the sollution for baldness...
because many men regarding do dht levels high or low still mantain their hair because i had a friend which used finasterid and he regrew the hair on his crown but the temples still receeded even after year of use then later it stopped in a place and stayed there ... correct me if im wrong but isnt the theory this?
dht-->cox-->pgd2--->male pattern baldness
maybe blocking pgd2 will stop hair loss but we need pge to grow hair dht is unrelevant and the reason it works is because reducing dht also reduces pgd2. thanks to squeegee we found that out now , i dont know where he finds this stuff but thank god for you , the most usefull poster ... what happend to boldy?
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well, for me, this is kind of all making sense now....when Propecia first came out, the big thing with it was that you start soon before the hair loss get's to a certain stage...why?? It would appear that DHT kicks off the process, but eventually the production of COX and PGD2 becomes self-sustaining and is not dependent on DHT...by limiting DHT production, hair follicles never get to the stage where the "fuel" of COX-PGD2 can take over without needing DHT anymore...so fighting hairloss needs to occur on two, maybe three fronts....this is why the BIG 3 works...Hairloss seems to be a very "staged" process

....having said all that, it still all comes down to DHT, in the end...if you can get the follicle back to normal health, then limiting DHT should be enough to sustain and you should be able to let go of the of COX-PGD2 treatment part...in theory....

squeegee, can you correct or elaborate??
 
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bornthisway

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baldnesssadness said:
honestly hard to say really. but i started with minoxidil together with cetirizine and i can tell you this it has been only some days and i get this vellus hair much lower than my hairline. When i was a kid i had really strong hair and clearly a norwood zero ,if the vellus hair grew to be normal hair i believe it would be the same hairline i had as a kid.
Click to expand...

Did you use minoxidil by itself before? If so, you're seeing a difference due to the addition of cetirizine? How much cetirizine are you using?
 
baldnesssadness

baldnesssadness

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i tried minoxidil in march.. but i quit after some days because it was so itchy ... now im using 10 mg everyday. I tried cetirizine for some weeks now , allmost 4 weeks and then it has went up and down in doses, but now im gonna stick with 10 mg because i read that antihistamines make you gain weight, i had very bad itching because of seboharric dermatitis and after i started with cetirizine the itching stopped completely so i decided to add minoxidil to the temples, and im getting better results than before, i hope the neogenic can provide some help too. its allmost a week with minoxidil and i have no itching , I reccomend this to everyone that reacted allergic to minoxidil before, use cetirizine for a week or two and try minoxidil then it can be different expirience than before. and since we block the pgd2 i guess the pge raises all the follicles.
 
Sparky4444

Sparky4444

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baldnesssadness said:
i tried minoxidil in march.. but i quit after some days because it was so itchy ... now im using 10 mg everyday. I tried cetirizine for some weeks now , allmost 4 weeks and then it has went up and down in doses, but now im gonna stick with 10 mg because i read that antihistamines make you gain weight, i had very bad itching because of seboharric dermatitis and after i started with cetirizine the itching stopped completely so i decided to add minoxidil to the temples, and im getting better results than before, i hope the neogenic can provide some help too. its allmost a week with minoxidil and i have no itching , I reccomend this to everyone that reacted allergic to minoxidil before, use cetirizine for a week or two and try minoxidil then it can be different expirience than before. and since we block the pgd2 i guess the pge raises all the follicles.
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the thing is how can you take anti-histamine everyday for the rest of your life?? That just can't be healthy for you
 
baldnesssadness

baldnesssadness

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dont believe im gonna take antihistamine of my life, i dont know how i should dosage it right now , maybe i take cetirizine from monday to friday only, but there is new medicine that i read about that is on fda trials, but for right now it works better than nothing, and i hope rather we can block cox2 since cox2 is the one that causing pgd2 in the first place blocking pgd2 can be up down but blocking cox will work much better? squeegee is there anything we can do to blox cox2?
 
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andres

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baldnesssadness said:
dont believe im gonna take antihistamine of my life, i dont know how i should dosage it right now , maybe i take cetirizine from monday to friday only, but there is new medicine that i read about that is on fda trials, but for right now it works better than nothing, and i hope rather we can block cox2 since cox2 is the one that causing pgd2 in the first place blocking pgd2 can be up down but blocking cox will work much better? squeegee is there anything we can do to blox cox2?
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Hi guys! Baldnessssadness how are you taking cetirizine? oral or topic? how many mg for day?


thnks!
 
baldnesssadness

baldnesssadness

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im taking it oral , 10 mg a day. My theory is that cox2 is the problem.. look it like this.

Your driving a car, and then you suddenly think about something that takes away you concentration, then suddenly you cant controll the car, and then you crash.

now think like this, driving car is dht its something we all have it in minimum or large doses, something that takes away concentration is cox2 , which is sending the messages for pgd2, now when you cant controll the car which represents pgd2 because something is starting which is not bad for you, and then the crash which represents baldness. the problem lies with in cox2 i think by blocking it you will have no balding... yes you can say that pgd2 causes baldness, but without cox2 it wouldnt even be there in the first place... pls correct me if im wrong..
 
Sparky4444

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baldnesssadness said:
im taking it oral , 10 mg a day. My theory is that cox2 is the problem.. look it like this.

Your driving a car, and then you suddenly think about something that takes away you concentration, then suddenly you cant controll the car, and then you crash.

now think like this, driving car is dht its something we all have it in minimum or large doses, something that takes away concentration is cox2 , which is sending the messages for pgd2, now when you cant controll the car which represents pgd2 because something is starting which is not bad for you, and then the crash which represents baldness. the problem lies with in cox2 i think by blocking it you will have no balding... yes you can say that pgd2 causes baldness, but without cox2 it wouldnt even be there in the first place... pls correct me if im wrong..
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I THINK one of the questions is what stimulates your system to produce PGD2....Some people think that Niacin increases PGD2 production, but I don't think that is accurate -- it releases PGD2 and flushes it out, but doesn't stimulate your body to produce more...or does it?? Maybe flushing PGD2 sends a signal to your body to produce more to make up the temporary depletion??

Man the body is one complicated thing

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ok...sorry if I am duplicating this information...from Wikipedia...

A 2012 research paper indicates a causal link between elevated levels of localized prostaglandin D[SUB]2[/SUB] and hair loss.[SUP][4][/SUP] Applied topically, the research found PGD2 prevents hair growth, and mice that were genetically inclined to produce higher levels of PGD2 had inhibited hair growth. The research also found PGD2 levels were much higher in balding scalp tissue than nonbalding scalp tissue. The paper suggested one of the receptors involved in production of PGD2, GPR44, would therefore be a therapeutic targets for androgenic alopecia in both men and women with hair loss and thinning.[SUP][5][/SUP]
Because PGD2's relation to asthma has been known for several years, several drugs that seek to reduce PGD2 levels through blocking the GPR44 level are already in clinical trials ****

So this is why the allergy med's being used...excuse my tardiness to the party....so GPR44 is the new 5-alpha -- block that and prevent PGD2 production...now what is GPR44 and what other functions does it play in the body?? Allergic reactions are important for our body so if we turn that switch off, that might not be a good thing
 
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bornthisway

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Agahi

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bornthisway said:
The oral route wouldn't yield any measurable benefits as far as hair growth is concerned.
Instructions on how to prepare the solution:
http://www.hairsite.com/hair-loss/board_entry-id-107887.html#p107946
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Ive been on it for about 2 months now orally, and I am certain it has helped at least a bit. finasteride for about a year now had leveled out and 6 years of Min had long ago leveled out. Cit did something for sure, my thinned area on my left temple has grown in and ive got short terminal hairs down to a point I didnt have as a child. If these hairs got longer Id have a perfectly NW0 hairline.
 
baldnesssadness

baldnesssadness

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same here!!! i have grown hair much more lower than my hairline too!!! but i still havent stopped the balding .... its still receeding...

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thank you so much... i will try this.. in the shortest time... but right now im kinda waiting for neogenic... even if its cosmetic as some may call it, it has great results 4% hair density and it grew 1700 hairs in 3 months the perfect maybe but as long as i can grow my those tiny hairs around my temples and hairline i would be a perfect norwood zero, btw have you tried this method with cetirizine?

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hmm allergic reactions are good for our body? can you try to explain why its good? i mean i see people with out food allergy or pollen allergy that has a better life quality than alergetics like me? and yes boyd is a complicated thing , but we must not give up... by understanding our body we will have a much better life quality.
 
Sparky4444

Sparky4444

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baldnesssadness said:
same here!!! i have grown hair much more lower than my hairline too!!! but i still havent stopped the balding .... its still receeding...

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thank you so much... i will try this.. in the shortest time... but right now im kinda waiting for neogenic... even if its cosmetic as some may call it, it has great results 4% hair density and it grew 1700 hairs in 3 months the perfect maybe but as long as i can grow my those tiny hairs around my temples and hairline i would be a perfect norwood zero, btw have you tried this method with cetirizine?

- - - Updated - - -

hmm allergic reactions are good for our body? can you try to explain why its good? i mean i see people with out food allergy or pollen allergy that has a better life quality than alergetics like me? and yes boyd is a complicated thing , but we must not give up... by understanding our body we will have a much better life quality.
Click to expand...

Allergic reactions are the body's way of attacking invasion of foreign substances that can possibly do harm...but somehow, that evolved to be a pain-the-***...I am just saying from a purist's approach
 
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bornthisway

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Agahi said:
Ive been on it for about 2 months now orally, and I am certain it has helped at least a bit. finasteride for about a year now had leveled out and 6 years of Min had long ago leveled out. Cit did something for sure, my thinned area on my left temple has grown in and ive got short terminal hairs down to a point I didnt have as a child. If these hairs got longer Id have a perfectly NW0 hairline.
Click to expand...

That's interesting you guys are seeing a difference via oral route. Lots of people take antihistamines daily but no such side effects are listed, with respect to cit, hair loss is a reported side effect. I might start applying it topically soon, mixed with minoxidil.

I would pick up neogenic when available but there is no North American distributor that I'm aware of.
 
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