Re: Nizoral becomes illegal in France
Here's what I found about Nizoral the tablet (which you DONT use to control dandruff)
"WARNINGS
NIZORAL tablet (not shampoo) has a potential for clinically important drug interactions. (See the section on “Interactionsâ€).
Decreased gastric acidity: Absorption is impaired when the gastric acidity is decreased. In patients also receiving acid neutralizing medicines (e.g. aluminium hydroxide) these should be administered at least 2 hours after the intake of NIZORAL. In patients with achlorhydria such as certain AIDS patients and patients on acid secretion suppressors (H2-antagonists, proton pump inhibitors) it is advisable to administer NIZORAL with a cola beverage.
The concomitant administration of terfenadine and astemizole with NIZORAL is contra-indicated. For combinations with other drugs see Interactions.
During NIZORAL treatment hepatitis has been reported. If symptoms or signs suggestive of hepatic dysfunction are detected, medication should be stopped at once. Patients on NIZORAL should be instructed to report any of the prodromal symptoms of hepatitis, such as fatigue associated with nausea or vomiting, jaundice, dark urine or pale stools, immediately and stop treatment.
A risk/benefit evaluation should be made before ketoconazole in cases of non-life threatening diseases requiring long treatment periods.
Factors increasing the risk of hepatitis are: females over 50 years of age, previous long-term treatment with griseofulvin, history of liver disease, known drug intolerance, long lasting treatment and concomitant use of liver compromising medication.
A mild transient asymptomatic increase in transaminases or alkaline phosphatase sometimes occurs. This asymptomatic reaction is harmless and does not necessarily require a discontinuation of the therapy but these patients should be monitored.
Patients on prolonged therapy (longer than 2 weeks) should have regular monitoring of liver function (before treatment, after 2 weeks and later on, monthly), particularly those patients with a known history of prior liver disease or an idiosyncrasy to other medicines. Should liver disease be confirmed, the therapy is to be discontinued.
After long-term griseofulvin treatment, it is advisable to wait for one month before starting NIZORAL treatment.
DOSAGE AND DIRECTIONS FOR USE
NIZORAL should be taken with meals for maximal absorption.
Chronic and recurrent vaginal candidiasis not responding to topical treatment:
Two tablets (400 mg) once daily with a meal for 5 days.
All other indications: One tablet (200 mg) once daily with a meal until at least one week after the symptoms have disappeared and until all cultures have become negative.
The dose of ketoconazole may be doubled to 400 mg if the clinical response is insufficient after a reasonable period of treatment.
The usual duration of treatment is as follows:
- Serious chronic mycoses of the skin and hair: 1 to 2 months;
- Systemic candidiasis: 1 to 2 months;
- Serious chronic mucocutaneous candidiasis: 6 to 12 months;
- Paracoccidioidomycosis and histoplasmosis: 2 to 6 months;
- Dermatophytes: 4 weeks."
It sounds like it's talking about something other than shampoo. I don't know about you, but I don't take shampoo internally
