Oleuropien Effect On Hair Growth Looks Promising??

[ahmad029]

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462586/

looking at the study gave me a new hope that this could be it.
oleuropien targets the wnt10b/beta catenin pathway and its dose dependent pattern is in accordance with sammumeds solution which also effect the same pathway. it gives higer growth at 0.6 mg/day and lower at heigher dose.
according to this study the molecule addresses almost all the good growth factors that we lack such as IGF-1,
VEGF, HGF, KGF.
and suppresses the bad protien knows as DKK-1.

i did some basic calculations and found that using sammumeds working percentage concentration we only require 1.5-1.7 mg/day of this compound daily in form of a topical.

As we all heard some annecdotes that olive oil reduce shedding. but according to the following study, the concentration of this component is too low in extra vergin olive for the purpose of regrowth
0.0mg/kg to 4mg/kg
how ever regular use may prevent hairloss.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227229/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227229/

 

[Seuxin]

Hello,

This was already discussed by a man named "Chemical". We read a few studies about thaht...a few peopes tried Oleuropein...with no results at all...Sorry.

 

[ahmad029]

how long did he use it ?

 

[dk1984]

how long did he use it ?

i used also oleuropein powder with dmso with no results at all

 

[GotHair?]

Yup used oleuropein. No changes.

 

[mr_robot]

Four months here, made no difference.

 

[wow-wow]

Even no decrease of shedding?

 

[ahmad029]

samumed is also using the same pathway and they revealed 10% increase in hair count after 3 month may be that is not cosmetically significant.
we know that some people have to use treatment for at least an year to see the result.

 

[ahmad029]

i used also oleuropein powder with dmso with no results at all

i have a bad experience with DMSO i used it for a week and my shedding increase due to it. i have read some where else too that it is bad for hair.
please tell the concentration you used from the study it looks like it do not follow the dose response curve.

 

[ahmad029]

Four months here, made no difference.

are you still using it.
please tell me the concentration.
which vehicle you are using.

 

[dk1984]

i have a bad experience with DMSO i used it for a week and my shedding increase due to it. i have read some where else too that it is bad for hair.
please tell the concentration you used from the study it looks like it do not follow the dose response curve.

my dosage was from 20mg to 100mg with 3 -5ml dmso with no results no side effects nothing...DMSO was harsh for my skin. Everytime i use it irritating and burning my skin

 

[ahmad029]

my dosage was from 20mg to 100mg with 3 -5ml dmso with no results no side effects nothing...DMSO was harsh for my skin. Everytime i use it irritating and burning my skin

i am not an expert even not a beginner in hairloss but in my openion most effective does would be 1.5mg-1.7mg higher dose will decrease the effectiveness.

 

[mr_robot]

are you still using it.
please tell me the concentration.
which vehicle you are using.

No I'm not still using it. I mixed I tablet with 75mg into 60ml bottle of minoxidil, i.e. 1.25mg per dosage.

 

[ahmad029]

thank you all

 

[ahmad029]

i used also oleuropein powder with dmso with no results at all

Yup used oleuropein. No changes.

Four months here, made no difference.

http://naldc.nal.usda.gov/download/18317/PDF

sorry guys but it seems like we are using degraded oleuropien. the above study indicate that oleuropien degraded rapidly with in 17days following extraction. please tell me if i get it right

 

[mr_robot]

http://naldc.nal.usda.gov/download/18317/PDF

sorry guys but it seems like we are using degraded oleuropien. the above study indicate that oleuropien degraded rapidly with in 17days following extraction. please tell me if i get it right

I have n't had time to read the whole thing, but what I understand is that the degradation is once the oleuropien is extracted from the leaf powder and then stored in water. The oleuropien in the tablets you get is basically leaf powder, if mixed in alcohol then it is pretty stable.

 

[dk1984]

I have n't had time to read the whole thing, but what I understand is that the degradation is once the oleuropien is extracted from the leaf powder and then stored in water. The oleuropien in the tablets you get is basically leaf powder, if mixed in alcohol then it is pretty stable.

oleuropein that i tested was https://www.rawpowders.co.uk/shop-by-category/health-and-skin/antioxidant/olive-leaf-extract-100-g