One of my hair follicles is the key for male pattern baldness cure

cyberprimate

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That would answer our question.
 

freakout

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cyberprimate said:
... scalp hair have a negative reaction to dht ...
Rozlyn Krajcik's team left an open suggestion that there is a growth inhibiting factor in humans other than DHT but did not mentioned blood supply.

Low blood supply IS an inhibitor of anything. Hypoxia is only a consequence of that. My question is, can hypoxia occur with sufficient blood flow in normal atmosphere?
 

freakout

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cyberprimate said:
... there seems to be a genetic difference between scalp follicles and body follicles...
Armandein and idontwanttobebalding cited two studies which suggests that follicle behavior is influenced by the recipient or host site.

While the horseshoe follicles thrive almost infinitely, their demise is greatly accelerated when transplanted to the galea area which suggests that they are genetically identical.
 

freakout

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The skin (scalp) is a highly adaptable organ. It is capable of stretching to more 4 times its size given enough time and shrink when necessary. The skin also has properties in elasticity which differ from each person .

A 'chronically active' 'tight scalp' should eventually allow it to stretch and recover its thickness. Whatever is keeping the scalp abnormally thin is not a tight scalp.
 

armandein

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freakout said:
The skin (scalp) is a highly adaptable organ. It is capable of stretching to more 4 times its size given enough time and shrink when necessary. The skin also has properties in elasticity which differ from each person .

Have you any study about the stretching and mechanical properties of scalp?
 

Bryan

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freakout said:
cyberprimate said:
... there seems to be a genetic difference between scalp follicles and body follicles...
Armandein and idontwanttobebalding cited two studies which suggests that follicle behavior is influenced by the recipient or host site.

Certain aspects of hair growth are influenced by the physical location of hair follicles on the body, but the course of androgenetic alopecia is NOT affected by that!

freakout said:
While the horseshoe follicles thrive almost infinitely, their demise is greatly accelerated when transplanted to the galea area which suggests that they are genetically identical.

BULLSHIT. You're just making that up.
 

cyberprimate

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What happens to SCALP follicles transplanted on the galea after say 20 YEARS?
 

cyberprimate

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Well…

25_bidenhair_lg.jpg
 

cyberprimate

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I'll rephrase my question: "What happens to SCALP follicles transplanted on the galea of the same man after say 20 YEARS?"
 

Bryan

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cyberprimate said:
I'll rephrase my question: "What happens to SCALP follicles transplanted on the galea of the same man after say 20 YEARS?"

They probably continue with the same fate that they originally had (prior to being transplanted at all). Isn't that rather obvious? :dunno:
 

freakout

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Joe Biden before the transplant in the 1980's. In this photo, his progression was more aggresive at the rear vertex .

More than twenty years later, he's bald again and was probably almost as bald ten years ago.

It's obvious they had to take donors from the horseshoe area which was enough to cover the entire recipient site.
 

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cyberprimate

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Bryan said:
cyberprimate said:
I'll rephrase my question: "What happens to SCALP follicles transplanted on the galea of the same man after say 20 YEARS?"

They probably continue with the same fate that they originally had (prior to being transplanted at all). Isn't that rather obvious? :dunno:

Any experimental evidence that horseshoe follicles of the same man "continue with the same fate that they originally had" 20 years after being transplanted on the galea? Pictures?
 

Bryan

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cyberprimate said:
Any experimental evidence that horseshoe follicles of the same man "continue with the same fate that they originally had" 20 years after being transplanted on the galea? Pictures?

Not to my knowledge, but would you even believe the evidence if you heard about it, and saw the pictures? Do you believe the results of Nordström's experiment? :dunno:
 

cyberprimate

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Bryan said:
cyberprimate said:
Any experimental evidence that horseshoe follicles of the same man "continue with the same fate that they originally had" 20 years after being transplanted on the galea? Pictures?

Not to my knowledge, but would you even believe the evidence if you heard about it, and saw the pictures? Do you believe the results of Nordström's experiment? :dunno:

But I do believe the Nordström's experiment results! I just have some reserves about the conclusions that one is supposed to give to it. As I said before, one can well imagine that long term structural damage of the follicles remains after transplantation on the arm, and makes it impossible for hair to grow thicker at least over the course of those several months, unless something is done to the follicles (finasteride, minoxidil,…).

As for the success of transplantation, only long term success like 20 years is really meaningful to me.
 

Bryan

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cyberprimate said:
Bryan said:
Not to my knowledge, but would you even believe the evidence if you heard about it, and saw the pictures? Do you believe the results of Nordström's experiment? :dunno:

But I do believe the Nordström's experiment results! I just have some reserves about the conclusions that one is supposed to give to it. As I said before, one can well imagine that long term structural damage of the follicles remains after transplantation on the arm, and makes it impossible for hair to grow thicker at least over the course of those several months, unless something is done to the follicles (finasteride, minoxidil,…).

So you use that silly idea as an excuse not to believe what almost ALL doctors and scientists currently believe about hair follicles: when it comes to androgenetic alopecia, they are donor dominant.
 

freakout

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I Broke the Mystery of Male Patten Baldness

idontwanttobebalding said:
Androgens can effect blood pressure through different means:

http://www.ncbi.nlm.nih.gov/pubmed/21271819
This is quite new. How do you find links like this?

Mercado's book already mentions androgens as blood pressure regulators thru the neurovascular system - years before this study.

What fascinates me is he's able to relate environment influences on behavior and behavior on the system and how the system influences CVDs and the formation of patterns!

While he mentions the galea, he discounts it as a contributing factor because it's a universal constant and can only be used as a reference in an equation.

Even more, you now have two new studies relating hair loss with stress. He already associates stress and hair loss - a type of hair loss that finasteride cannot treat. We know the stress levels are higher in industrialized areas.
 

cyberprimate

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Bryan said:
cyberprimate said:
Bryan said:
Not to my knowledge, but would you even believe the evidence if you heard about it, and saw the pictures? Do you believe the results of Nordström's experiment? :dunno:

But I do believe the Nordström's experiment results! I just have some reserves about the conclusions that one is supposed to give to it. As I said before, one can well imagine that long term structural damage of the follicles remains after transplantation on the arm, and makes it impossible for hair to grow thicker at least over the course of those several months, unless something is done to the follicles (finasteride, minoxidil,…).

So you use that silly idea as an excuse not to believe what almost ALL doctors and scientists currently believe about hair follicles: when it comes to androgenetic alopecia, they are donor dominant.

Problem is that "silly idea" has never been proven wrong. I'm still curious about the beauty of donor dominant hair after 20 years or more. Big business, but no picture?
 

cyberprimate

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Joe Biden's transplanted follicles are from another guy. Transplant any non-balding guy's follicles on anybody's head or butt and it will grow forever… What I'm interested in seeing is how Joe Biden's back or side follicles would behave after 20 years on his crown. 10 years after puberty my hair still looked fine; 20 years later it's a different story…
 
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