Please give me an update?

[JimmyJones]

I used to lurk on these forums and read about companies such as Intercytex etc. I got a horrible side effect from Propecia and now wear a hair system. I would like to know which company is nearest to sorting out this problem of ours? I have heard of various companies such as Replicel; Follica etc. I don't understand why this is taking so long; clone a hair on the back of your head; then implant it to the top like a hair transplant. Why is this taking so long? Are these doctors mentally challenged? I am looking for information from the knowledgeable members on this forum of the realistic timeline of these new companies. Opinions of people that have researched this area would be appreciated not just negativity. Thank you.

 

[cthulhu2.0]

I used to lurk on these forums and read about companies such as Intercytex etc. I got a horrible side effect from Propecia and now wear a hair system. I would like to know which company is nearest to sorting out this problem of ours? I have heard of various companies such as Replicel; Follica etc. I don't understand why this is taking so long; clone a hair on the back of your head; then implant it to the top like a hair transplant. Why is this taking so long? Are these doctors mentally challenged? I am looking for information from the knowledgeable members on this forum of the realistic timeline of these new companies. Opinions of people that have researched this area would be appreciated not just negativity. Thank you.

It turns out, growing hair is not as easy as growing grass, since the hair follicle is an organ itself. In the near future, all hope lies with cb-03-01, which is almost done with phase II for acne and works as a topical 5 alpha reductase inhibitor. Another one that has garnered a lot of research recently is topical finasteride using lipid nanoparticles. The goal is to keep the drug deposited in the hair follicle instead of going systematic. The big start up companies like Follica, Replicel, Histogen, etc. will not have anything in the near future for a couple of reasons, the main one being funding. In fact, according to a hairloss community member (Desmond) who went to the World Hair Loss Congress a few months ago, Follica is at a standstill due to funding and won't have anything in the near future(5 years), which were the words of Dr. Cotsarellis.

 

[JimmyJones]

Thank you for taking the time to reply.

 

[hellouser]

It turns out, growing hair is not as easy as growing grass, since the hair follicle is an organ itself. In the near future, all hope lies with cb-03-01, which is almost done with phase II for acne and works as a topical 5 alpha reductase inhibitor. Another one that has garnered a lot of research recently is topical finasteride using lipid nanoparticles. The goal is to keep the drug deposited in the hair follicle instead of going systematic. The big start up companies like Follica, Replicel, Histogen, etc. will not have anything in the near future for a couple of reasons, the main one being funding. In fact, according to a hairloss community member (Desmond) who went to the World Hair Loss Congress a few months ago, Follica is at a standstill due to funding and won't have anything in the near future(5 years), which were the words of Dr. Cotsarellis.

They received nearly 30 million dollars in funding with conditions (they meet goals). Japan's new change in DE-regulation of stem cell therapies and clinical trials will allow biotechs to release a treatment while they're ongoing DURING phase II trials, also with conditions. That essentially means; a few years for a release of a treatment.

CB-03-01 is NOT 'all the hope' because it is NOT a cure, it's still a band aid solution like Finasteride.

 

[cthulhu2.0]

They received nearly 30 million dollars in funding with conditions (they meet goals). Japan's new change in DE-regulation of stem cell therapies and clinical trials will allow biotechs to release a treatment while they're ongoing DURING phase II trials, also with conditions. That essentially means; a few years for a release of a treatment.

CB-03-01 is NOT 'all the hope' because it is NOT a cure, it's still a band aid solution like Finasteride.

Which one received nearly 30 million dollars with conditions? So we're going to have to travel to Japan to get these treatments during testing? I thought the takeaway from Desmond's trip was that none of these companies were close. Maybe you can shed some light on this insider knowledge

 

[hellouser]

Which one received nearly 30 million dollars with conditions? So we're going to have to travel to Japan to get these treatments during testing? I thought the takeaway from Desmond's trip was that none of these companies were close. Maybe you can shed some light on this insider knowledge

They're ALL 'close'. 30 million was given to Replicel from Shiseido in Japan. You really shouldn't be complaining about WHERE a cure/treatment is available. If you've got money to blow away on stem cell therapy, you SHOULD have money to blow away on a flight to Japan.

And yes, the deregulation is real, its been reported and confirmed. Basically, if Dr. Lauster's team is as far as we hope they are and they select Japan for trials, we're not all that far away. My only hope is that some team DOES chose Japan, USA is not the 'centre of the universe', its not as if its the only place where trials can take place, especially with its stone age regulation.

Japan > USA

 

[Kirby]

CB-03-01 is NOT 'all the hope' because it is NOT a cure, it's still a band aid solution like Finasteride.

It'll be a pretty damn awesome thing to have though!

 

[JZA70]

You really shouldn't be complaining about WHERE a cure/treatment is available. If you've got money to blow away on stem cell therapy, you SHOULD have money to blow away on a flight to Japan.

Very true. I don't know if Desmond asked Dr. Lindner where they plan to commercialize. It might be worth it to send Dr. Marx an email and see what he says. I'm sure they're aware of japans new regulations, let's just hope they take advantage of it.

 

[hellouser]

Very true. I don't know if Desmond asked Dr. Lindner where they plan to commercialize. It might be worth it to send Dr. Marx an email and see what he says. I'm sure they're aware of japans new regulations, let's just hope they take advantage of it.

I would gladly, GLADLY fund Dr. Lauster's team through crowdfunding but absolutely ONLY if they agreed to push the trials as fast as possible through Japan. If people we're given the promise of an ACTUAL quick release (none of this Cotsarelis 5 year bull****) then they'd much more reason to actually donate.

Remember: if only 1 in 10 people in USA alone donated only 50 cents, we'd have 15 million dollars. We'd have funding enough for years to come and we'd actually defeat this fvcking disease. And that's crowdfunding at such a low donation from USA alone, a global reach could have ridiculous rewards.

- - - Updated - - -

It'll be a pretty damn awesome thing to have though!

Sure... but it's not out yet and won't be for at least 2-3 more years. Hard to get a woody from that.

 

[JZA70]

I would gladly, GLADLY fund Dr. Lauster's team through crowdfunding but absolutely ONLY if they agreed to push the trials as fast as possible through Japan. If people we're given the promise of an ACTUAL quick release (none of this Cotsarelis 5 year bull****) then they'd much more reason to actually donate.

If Dr. Lauster and his team actually pulled it off, crowd funding will be nothing more than pocket change to them. Like you told me earlier, people won't fund someone unless there is a guaranteed promise of something, that's why no one gives a sh1t to fund Dr. Xu or Cotsarelis, our money is guaranteed but their work isn't. If Dr. Lauster and his team have actually cured hair loss and can prove it, they won't need crowd funding. Investors would be flocking to them and throwing cash at them like no tomorrow.

 

[Python]

So have we had any word on Desmond yet?

 

[JZA70]

So have we had any word on Desmond yet?

Well if nothing has been posted on BTT, then it's safe to say no.

 

[hellouser]

If Dr. Lauster and his team actually pulled it off, crowd funding will be nothing more than pocket change to them. Like you told me earlier, people won't fund someone unless there is a guaranteed promise of something, that's why no one gives a sh1t to fund Dr. Xu or Cotsarelis, our money is guaranteed but their work isn't. If Dr. Lauster and his team have actually cured hair loss and can prove it, they won't need crowd funding. Investors would be flocking to them and throwing cash at them like no tomorrow.

We could be a contributing factor to get the funds ASAP though. I doubt they'd say 'no' to another large sum of money.

 

[cthulhu2.0]

We could be a contributing factor to get the funds ASAP though. I doubt they'd say 'no' to another large sum of money.

I don't think the crowdfunding idea would eve work. The hairloss community (well those who care about their hairloss) is simply not that united. Yes there are some fervent supporters like you hellouser, desmond, etc.. But you need 100's of thousands of people contributing and for something that be a lost cause. Just because we pump them more money, doesn't mean they will reach the end goal. Besides, why should we trust companies like follica, who keep everything secret.

 

[JZA70]

We could be a contributing factor to get the funds ASAP though. I doubt they'd say 'no' to another large sum of money.

I think we both know that crowd funding for hair loss will never happen.

I sent an email off to Dr. Marx asking about an estimated timeline and if he has any interest in launching in Japan.

 

[JimmyJones]

So from what you have all said; CB is the next drug to come out for hair loss and Replicell is the predicted to be the first company to cross the finish line?

 

[Python]

I think it's not all about how much money we would be able to raise. If we raise something like $100k dollars, investors will see how desperate we are and will make this project a high priority. On the negative side, thy might be willing to charge even more.

 

[c_super2]

I don't understand if researchers are trying to answer the question "How does hair grow?" Then look at hair in the permanent zone and compare with the balding zone. It seems very simple yet they cant tell us how hair grows.

 

[hellouser]

I think we both know that crowd funding for hair loss will never happen.

I sent an email off to Dr. Marx asking about an estimated timeline and if he has any interest in launching in Japan.

The gears in his head will start to turn once enough of us make it known to him that there IS a very real possibility to fund the project.

 

[JZA70]

I don't understand if researchers are trying to answer the question "How does hair grow?" Then look at hair in the permanent zone and compare with the balding zone. It seems very simple yet they cant tell us how hair grows.

That doesn't tell us how hair grows though.

Read through this and you'll see how complicated it is - http://www.nature.com/ncomms/journal/v3/n4/full/ncomms1784.html

The gears in his head will start to turn once enough of us make it known to him that there IS a very real possibility to fund the project.

True, but if he has no interest in Japan then there's no point. Every other country will make us wait 10+ years for trials. No one is going to fund that.