Polarity News. Polarity Makes Breakthrough In Generating Skin With Hair Follicles.

c_super2

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Polarity today announced pre-clinical results demonstrating that the Company’s lead product, SkinTE™, regenerated full-thickness, organized skin and hair follicles in third degree burn wounds. The findings represent the first known successful regeneration of skin and hair in full-thickness swine wound models, the standard animal model for human skin. The Company expects to initiate a human clinical trial evaluating the autologous homologous SkinTE™ construct in the third quarter of 2017.

In pre-clinical models of full-thickness burns and wounds, SkinTE™ demonstrated scar-less healing, hair follicle growth, immediate complete wound coverage, and the progressive regeneration of all skin layers including epidermis, dermis and hypodermal layers (www.polarityte.com/products/skinte). The SkinTE™ product, which utilizes the subject’s own skin, is prepared and used to treat the wound in less than 24 hours.

Source: https://www.nextbigfuture.com/2017/...kin-tissue-and-other-tissues-will-follow.html
 

saymsaym

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Awesome, it reminds me the guy who regrew a full head of hair after having burned his bald scalp by accident.

It also stands for Follicà' s approach, i think wounding is something big in this fight against hair loss.



Lets hope this new actor in the field accelerate the research about wounding and hairloss. Eager to have more info on how it works. They set up a potential human trial as soon as Q3 2017 while they are totally new, looks like they are quite confident.

Good luck everyone
 

saymsaym

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Moreover they say the treatment lasts only 24h, so things could move forward very fast, at least it looks like we will know what they are capable of in only a few months
 

Hairloss2020aga

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Just read through most of that source file provided by op...

It honestly sounds like a better version of Replicel that actually works and they mention a potential application for hair loss.

The most amazing part is their release date on their pipeline: First half of 2018!!!!!! Are you kidding me? That's crazy fast. It's taken replicel, histogen, a decade each to get close.
 

br1

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Red flag to me, then. We'll know pretty soon. I bet we won't hear from them anymore.

And what you mean by a replicel that works? Replicel DOES work. They are running phase 2 trials with read out next year. I prefer a professional company doing that, rather than those "miraculous" ones, which make wonderful claims with colourful websites and press releases, but don't deliver nothing..

Just read through most of that source file provided by op...

It honestly sounds like a better version of Replicel that actually works and they mention a potential application for hair loss.

The most amazing part is their release date on their pipeline: First half of 2018!!!!!! Are you kidding me? That's crazy fast. It's taken replicel, histogen, a decade each to get close.
 

coolio

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And what you mean by a replicel that works? Replicel DOES work. They are running phase 2 trials with read out next year. I prefer a professional company doing that, rather than those "miraculous" ones, which make wonderful claims with colourful websites and press releases, but don't deliver nothing..

Don't count your Replicel hairs before they've hatched. They have been known to bullsh*t investors before. Ask anyone who was following the hair multiplication race for a long time.
 

That Guy

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Red flag to me, then. We'll know pretty soon. I bet we won't hear from them anymore.

I disagree, this company seems perfectly legitimate from what I can see. Great pictures on their website, credible people on staff, etc. Pretty excited to see where this goes, tbh.

Don't count your Replicel hairs before they've hatched. They have been known to bullsh*t investors before. Ask anyone who was following the hair multiplication race for a long time.

Jesus Christ

All of their results were good and there's no way they've bullshit one of the oldest and largest cosmetics firms into licensing their technology and custom-building facilities for a product that doesn't work. I've been studying and writing more than I really wanted to about that company since March and the only investor complaints I've been able to see in that sea of information is "you're taking too damn long".

Every post I see from you is casting doubt in light of positive information via some conspiracy theory with nothing to back it up. I'm guessing you've been following the hair multiplication race for a long time, so enlighten us all as to how investors have been bullshit by this company?

Everyone to you is a liar. Tsuji's team are liars when they say their research has shown them methods of solving epithelial culturing, despite putting their money where their mouth is on literally every thing they've said they can do thus far; RepliCel has groundbreaking results for all of their developing products and you say we can't trust them; Follica's technology is rooted in research that is known to cause hair growth and is ready to be put through its final trial and you still suggest they probably have nothing, as I recall.

Or maybe, just maybe, the science is advancing just like science always does.

It's getting real annoying that the "hairloss community" refuses to accept that and it says a lot about these individuals relationship with hairloss.
 

Afro_Vacancy

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A Utah paper and elsewhere that reported on them say they hope to have it on the market next year for treating burns and I've lost it but they had a chart about their pipeline.

The balls on these guys...

Thanks for being on top of things.
 

chemicalbrother

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time to pick up a couple of their stock?
 

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Dave721

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You guys are over reacting to this a bit I think. Even if it is true, no mention of using this for alopecia. You would either need your skin removed and this graphed on, or somehow grow another scalp worth of hair somewhere else and have it transplanted. Not saying it doesn't hold promise for hair cloning in the future, but I would not bet on getting a new scalp in 2018.
 

That Guy

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You guys are over reacting to this a bit I think. Even if it is true, no mention of using this for alopecia. You would either need your skin removed and this graphed on, or somehow grow another scalp worth of hair somewhere else and have it transplanted. Not saying it doesn't hold promise for hair cloning in the future, but I would not bet on getting a new scalp in 2018.

It literally says right on the company's website that if successful in the burn market, they will move into other areas such as regeneration for scars and cosmetic treatment as well as hair regeneration.

Thanks for being on top of things.

That's what she said.

Also, no prob
 

Tano1

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So glad to see everyone is racing with regenerative skin!

Just think, this would solve scars, burns and possibly even hair too!
 

That Guy

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So glad to see everyone is racing with regenerative skin!

Just think, this would solve scars, burns and possibly even hair too!

I definitely think that the two will go hand in hand to some degree.

Maybe I'm just brosciencin', but I find it odd that people have all this doubt that Tsuji will "solve the cell culturing problem" when his lab has also grown fully-functioning murine skin and skin contains types of epithelium. This group also demonstrates it's possible with pigs, which are the most suitable substitute for human skin in testing.

If it's possible to grow more, full-thickness, fully-functional skin that also grows hair follicles and glands from a small sample of skin and you can multiply that skin as much as you want, it stands to reason that within that method may be a means of getting all the epithelial cells you need for just the hair.

After all, the biopsy they need for the hair multiplication will come with skin samples as far as I know.

Could be wrong, but I would not be shocked if the answer is found in skin multiplication.
 

coolio

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Jesus Christ

All of their results were good and there's no way they've bullshit one of the oldest and largest cosmetics firms into licensing their technology and custom-building facilities for a product that doesn't work. I've been studying and writing more than I really wanted to about that company since March and the only investor complaints I've been able to see in that sea of information is "you're taking too damn long".

Every post I see from you is casting doubt in light of positive information via some conspiracy theory with nothing to back it up. I'm guessing you've been following the hair multiplication race for a long time, so enlighten us all as to how investors have been bullshit by this company?

Everyone to you is a liar. Tsuji's team are liars when they say their research has shown them methods of solving epithelial culturing, despite putting their money where their mouth is on literally every thing they've said they can do thus far; RepliCel has groundbreaking results for all of their developing products and you say we can't trust them; Follica's technology is rooted in research that is known to cause hair growth and is ready to be put through its final trial and you still suggest they probably have nothing, as I recall.

Or maybe, just maybe, the science is advancing just like science always does.

It's getting real annoying that the "hairloss community" refuses to accept that and it says a lot about these individuals relationship with hairloss.


After you get done insulting me, go re-check who has been saying what about which program.

I'm not the one bashing Follica. I think they are probably our best near-term hope for anything and I'm convinced they will be offering more than dermarolling+minoxidil level results. I have always been saying this.

The worst thing I have said about Tsuji is that it's not smart to assume he has solved the cell induction problems based on some "I think I've got it" word in the grapevine. Everyone's failure to solve that problem has been single-handedly keeping hair off our heads for over a decade now and this is not the first time somebody has been optimistic about sorting it out. No offense to Tsuji but they haven't got it until they've got it.

I do bash Replicel. They have a history of selling themselves hard (whereas Follica decidedly does not) and much of their science amounted to a more rudimentary version of the ICX/Aderans program that Ken Washenik spearheaded. They have dumped big money into having their stock professionally hyped right before releasing crappy results that were hardly over baseline in the big picture - defend that if you want but I call it bullsh*tting investors. This operation seems more interested in finding something re-sellable than curing baldness. That doesn't make them evil sadistic human beings but it means I don't have much faith in unproven claims about their progress.
 

br1

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Their trial was for safety. It demonstrated to be safe (5 yrs data), and you are talking about "crappy results"?

Don't get it.
 

coolio

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Their trial was for safety. It demonstrated to be safe (5 yrs data), and you are talking about "crappy results"?

Don't get it.

This was several years back. They had their stock hyped by an expensive marketing firm right before they released results with hardly any results.
 

br1

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This was several years back. They had their stock hyped by an expensive marketing firm right before they released results with hardly any results.

OK, you clearly have no idea. Get the facts together.
 

coolio

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OK, you clearly have no idea. Get the facts together.

Okay, correct me. I may indeed be wrong.

I will freely admit I gleaned that info from other people's discussions of what was going on, rather than reading all the Replicel releases/news sources myself.
 
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