Psychogenic (nocebo) effects of finasteride - Lets talk estrogen/dopamine/PDE5

Rayan27

New Member
Reaction score
0
Lets pen down some facts first

- 26 year old, have been on fina (.25mg eod) for 7 months and has completely halted any and all hair loss.
- Last few months libido has dropped from 3 times a week horny sex to maybe 1-2 a week meh.
- Noticed I am not fantasizing as much as I do, Almost never start out sex with my GF out of hornyness, 9 out of 10 times she instigates it
- The hornyness usually comes after she starts stroking me or giving head, also become flacid way more easily
- Had my T levels checked out before finasteride, came in borderline low (350ng/dl which is about 11nmol)

Now what has lead me to think that this just might all be psychogenic?

- Studies show most sexual adverse events are due to nocebo effect
- Rates of sexual events usually dissipates after a year of continued usage
- I am prone to anxiety/have had OCD when I was younger which I got CBT for.
- I get good morning wood about 2-3 times a week

What have I tried?
- Cialis: 2.5mg EOD works great for me, keeps my erection up and battles flaccidness. Also the feeling of getting an erection at the mere thought of sexual things creates a positieve feedback loop. But I don't want to become dependent on this at such a young age....

- Aromasin: 5mg twice a week in conjunction with finasteride, raises my libido and energy but gives me insane shedding on this.

- Cabergoline: at a mere 0.1 mg twice a week, without a doubt the strongest libido booster I have EVER used. Absolutely insane bordering on hyperseksuality. I quit this because the urges for sex are too much too handle. Also it has been implicated in dopamine withdrawal syndrome for people who experience impulse control disorder issues (OCD) and compulsive disorder (hyper sexuality/gambling/compulsive shopping) --> study here http://www.medscape.com/viewarticle/833495#vp_2

I am not sure where to go from here, quitting finasteride is not an option. I have been bullied extremely in my younger years for my oddly shaped head, bordering on thoughts of suicide. Growing up I have become extremely confident and good looking with my body and hair/face. Going back to my oddly shaped head times is just not an option. So how does one go about battling psychogenic side effects? Should I go the medical route, or just do nothing and see where things end up in a few months/year.

Help me out bro's, what do I do
 

buckthorn

Banned
My Regimen
Reaction score
5,210
Just keep going with it then and hopefully the side effects will be reduced or go away.
 

nate30

Member
Reaction score
7
I unfortunately never had a hormonal profile done before I started Finasteride (possibility of sexual issues wasn't well documented back then), but my T was also borderline when I came off it (around 350 ng/dl). It's been several years since and I recently went back to get my T checked, came back as 460 ng/dl that time, although free T was still on the low end. I do think your likelihood of sexual sides increases if you had lower T to begin with.

I'm not sure how to help if you're determined to take finasteride, but be careful with the cocktail of hormone altering drugs you're taking. You're right to be concerned about taking Cabergoline (a dopamine agonist) long term. I wouldn't worry about anything being seriously wrong if you're still able to get morning wood from time to time, but in my opinion it's best if you just stick with Cialis.
 

Rayan27

New Member
Reaction score
0
I unfortunately never had a hormonal profile done before I started Finasteride (possibility of sexual issues wasn't well documented back then), but my T was also borderline when I came off it (around 350 ng/dl). It's been several years since and I recently went back to get my T checked, came back as 460 ng/dl that time, although free T was still on the low end. I do think your likelihood of sexual sides increases if you had lower T to begin with.

I'm not sure how to help if you're determined to take finasteride, but be careful with the cocktail of hormone altering drugs you're taking. You're right to be concerned about taking Cabergoline (a dopamine agonist) long term. I wouldn't worry about anything being seriously wrong if you're still able to get morning wood from time to time, but in my opinion it's best if you just stick with Cialis.
Why did you came off? Any other sides?
What do you know about cabergoline
 

nate30

Member
Reaction score
7
I came off due to erectile and sensitivity issues (and in my case it wasn't due to the nocebo effect as I only starting researching Finasteride AFTER the fact). Before then I had the typical finasteride sides like reduced and watery ejaculate, lack of morning wood, somewhat puffier nipples. I don't know much about Cabergoline issues specifically, but apparently there's some evidence that it can supposedly increase your chances of heart valve problems. But in general I'd be wary of any drugs that "play" with dopamine levels or dopamine receptors, as they could presumably lead to dependence and hormone or receptor downregulation. A somewhat milder approach might be supplementing with L-Dopa (Mucuna pruriens), but I think even that has the same kinds of issues long term.
 
Top