Put your hands up if you take dutasteride!

[baso80]

Anyone buying dutasteride within europe? from which site?

 

[Slartibartfast]

Generic or actual GSK Avodart? Which one you want will affect the answer.

Aussie: I'm going to take these bastards down, the cost be damned....

More seriously: I'd only put myself in the 'moderate responder to Minoxidil' category, hence my interest in Prox-N. In fact I think I'll be starting with that and saving the Xandrox 15 for a later date.

Keep up the good fight,
Slarti

 

[Bryan]

I was under the impression that upping the dosage would make your prostate shrink more.

The propecia dosage for example after a year will only shrink the prostate negligibly, yet significantly stop enough dht at that dosage to prevent hair loss. Anything above that dosage, then your trying to effect more than just your hair, your trying to shrink your prostate.

I've now verified that your claim is incorrect. Finasteride has the same relatively "flat" dose-response curve, whether it's used for the prostate or for male pattern baldness. Here's an excerpt from the excellent review article "Finasteride", by Roger S. Rittmaster, in The New England Journal of Medicine, Jan. 13, 1994:

"In a large phase 3 trial of finasteride, 895 men with benign prostatic hyperplasia received placebo, 1 mg of finasteride, or 5 mg of finasteride daily for one year.(32) Eighty-eight per cent of the men completed the study. Prostate volume decreased by 18 per cent in the men who received 1 mg of the drug and by 19 per cent in those who received 5 mg.

32. Gormley, Stoner, Bruskekewitz et al. The effect of finasteride in men with benign prostatic hyperplasia. N Eng J Med 1992;327:1185-91."

 

[hairrific]

That study was for men with benign prostatic hyperplasia. What about those with male pattern baldness and not benign prostatic hyperplasia. Is it the same?

OK, "Prostate volume decreased by 18 per cent in the men who received 1 mg of the drug and by 19 per cent in those who received 5 mg."

That is only a 1% difference between 1mg and 5mg finasteride so taking more (5%) is not going to do much more to the enlarged prostate. Good to know if you have benign prostatic hyperplasia.

My claim was that men with male pattern baldness taking 1mg Propecia, their prostate shrinks by a very negligible margin.

 

[CCS]

OK, "Prostate volume decreased by 18 per cent in the men who received 1 mg of the drug [finasteride] and by 19 per cent in those who received 5 mg."

decreased prostate size? Scary. I hope it does not also decrease penis size. No studies have been done on it for that. Just lots of finasteride users saying they have not noticed a difference. I think mine was 5.2 inches 3 years ago, and now is 4.9, but I could be wrong. Maybe I just need to get fully arroused or something.

 

[Bryan]

That study was for men with benign prostatic hyperplasia. What about those with male pattern baldness and not benign prostatic hyperplasia. Is it the same?

Is WHAT the same? State your question precisely.

OK, "Prostate volume decreased by 18 per cent in the men who received 1 mg of the drug and by 19 per cent in those who received 5 mg."

My claim was that men with male pattern baldness taking 1mg Propecia, their prostate shrinks by a very negligible margin.

I wouldn't say that 18% is a "very negligible margin". Face it: you were wrong in what you said. There's very little difference between 1 mg and 5 mg in their effects on the prostate, regardless of what you're specifically using the drug for (hairloss prevention, or prostate reduction).

 

[HughJass]

OK, "Prostate volume decreased by 18 per cent in the men who received 1 mg of the drug [finasteride] and by 19 per cent in those who received 5 mg."

decreased prostate size? Scary. I hope it does not also decrease penis size. No studies have been done on it for that. Just lots of finasteride users saying they have not noticed a difference. I think mine was 5.2 inches 3 years ago, and now is 4.9, but I could be wrong. Maybe I just need to get fully arroused or something.

oh dear...

 

[JWM]

Anyone know what Merlinopharma is charging for Avodart these days?

 

[Jack]

Anyone know what Merlinopharma is charging for Avodart these days?

180CHF(~154$) for 90 and 30CHF for shipping. You may want to order bulk

 

[JWM]

Thanks Jack

 

[Nuli]

I've read more than once, that people getting sides from finasteride have tried dutasteride and experience no sides at all. Is there any logic behind this? I dont see how reducing your dht by 90+% instead of 70% could cause sides to go away. It just dosent make sense.

 

[hairrific]

That study was for men with benign prostatic hyperplasia. What about those with male pattern baldness and not benign prostatic hyperplasia. Is it the same?

Is WHAT the same? State your question precisely.

I don't doubt that If you have benign prostatic hyperplasia then 1mg finasteride will decrease Prostate volume by 18 per cent. That's the nature of the beast.

But what about all of us with male pattern baldness and healthy prostates, who do not have benign prostatic hyperplasia, does 1mg finasteride decrease Prostate volume by 18 per cent also?

 

[Bryan]

I don't doubt that If you have benign prostatic hyperplasia then 1mg finasteride will decrease Prostate volume by 18 per cent. That's the nature of the beast.

Okay, that's good. You accept that the dose-response curve for finasteride is pretty "flat", regardless of whether you're treating BPH or male pattern baldness.

But what about all of us with male pattern baldness and healthy prostates, who do not have benign prostatic hyperplasia, does 1mg finasteride decrease Prostate volume by 18 per cent also?

I have a couple of rather extensive review articles of finasteride, and neither one of them has any information about its effect on normal prostates. However, I wouldn't be surprised if it has somewhat less of an effect on them than it has on enlarged ones (BPH).

 

[1750]

I've read more than once, that people getting sides from finasteride have tried dutasteride and experience no sides at all. Is there any logic behind this? I dont see how reducing your dht by 90+% instead of 70% could cause sides to go away. It just dosent make sense.

for me this was complete bullsh!t!!!!
dutasteride had considerably exaggerated sides over finasteride.
to this day I do not think the family jewels or my semen volume has returned to normal working order and I have 2cm of breast tissue to thank finasteride and dutasteride for!

dutasteride is EVIL and the equivalent of castrating yourself IMO

 

[TAINTED-MEAT]

I have taken Avodart for over two and a half years now. I am very pleased with the results. I have pretty much maintained what I had, although my temples may be a bit thinner. In my pre-Avodart days I was losing ground faster than France!

 

[Timi]

i have take Avo 2Year
my Hair get fast worse

when i have take a dutasteride my Face-Head become a red Color
and burning-my Bodyskin burns

i dont know was this a Allergic Reaction
or other Hormon Problems

i have take Arimidex i have think to mutch Estrogen
but it helps nothing my Body burns away

for me was finasteride always the best
works 13years good

i was a Idiot to make a dutasteride attempt

Timi

 

[kalbo]

I'm not sure if there's any truth to the idea that dutasteride users experience less side effects than finasteride users. I guess maybe I'm just one of the unlucky ones because I used finasteride for almost 2 years and had maybe minor side effects that went away, like a rashes on my face (but that was probably caused by minoxidil).

However, using dutasteride for one year killed my libido. Well, it didn't actually "kill" it completely, just lowered it substantially. Silly me for continuing to use it though considering that not only was it not working on my hair, but it was also doing damage to the rest of my body.

 

[hairrific]

I see allot of people take dutasteride daily. Does it make since to take dutasteride every three days or something like that instead of every day? The point I am trying to make is that the dosage and schedule is for treatment of enlarged prostate. Wouldn't something less be better suited for male pattern baldness especially considering the long half life?

 

[Bryan]

I see allot of people take dutasteride daily. Does it make since to take dutasteride every three days or something like that instead of every day? The point I am trying to make is that the dosage and schedule is for treatment of enlarged prostate. Wouldn't something less be better suited for male pattern baldness especially considering the long half life?

Tell me what you think the half-life has to do with it.

 

[hairrific]

Let me ask it this way.

Concerning Avodart or dutasteride: Would a different dosing schedule be better for male pattern baldness instead of the .5mg every day which is recommended for BPH. For example .5mg every other day or every three days for male pattern baldness?