Retin A plus minoxidil

[Aj6543]

Has anyone had any success using Retin A plus minoxidil?

 

[Bryan]

Why aren't you asking the following question instead?

"Has anyone had any success using Retin A?"

 

[Jacob]

And there's the question police :shakehead:

 

[otis]

BRYAN
finasteride for hairloss was indeed an "accidental discovery".
It was made for enlarged prostate and hair growth was a side effect.
In fact every drug that is approved for hair loss today was accidenral. Minoxidl was the first, it was for high blood pressure.

 

[Bryan]

BRYAN
finasteride for hairloss was indeed an "accidental discovery".
It was made for enlarged prostate and hair growth was a side effect.

I assume you're just joking. This issue has been discussed by me and others for YEARS, and what you said above is incorrect.

 

[otis]

And why am i incorrect ,It was Proscar that came out for the prostate. If you have any facts that would say other wise please post. Thanks

 

[Bryan]

Once again, I have to assume that you're just joking, especially based on the fact that you joined this group in June of 2005. I have talked about this issue repeatedly over the years, and even put it in my signature file!

 

[otis]

Maybe you did speak about it for years but you were wrong The Fact is that Proscar was aproved for the prostate. Side effects were hair growth.. I no my doctar put me on Proscar first. Then it was approved for hair loss 1mg Propecia. Those are the facts.
GLTA

 

[Bryan]

If you're so determined to believe all that silliness, based just on what was "approved" first by the FDA, I don't think you'll listen to reason and believe what a doctor tells you (yes, a doctor fully supported what I said about that).

I'll have to give you one thing, though: this is the first time in YEARS that anybody has ever brought up that ridiculous issue again about finasteride for male pattern baldness being an "accidental" discovery!! :laugh:

 

[otis]

Bryan PM me with your findings.
Thanks

 

[Bryan]

Okay, I found the relevant postings over on HLH. These were written by "jfromm", who is a physican. He supports everything I say about finasteride, and wrote the following posts on HLH. First the very bottom paragraph, then he wrote the paragraph in the middle a few years later in response to still more people who just couldn't believe that Merck had planned all this, all along! The paragraphs he wrote are very similar, but I include both of them for the sake of completeness:

Bryan is right--finasteride was CLEARLY designed to treat male pattern baldness. I wrote about this 5 years ago on this site, but I'm not sure the record is available.

To reiterate, the evidence is the following: Merck published a paper in the middle of May or June 1988 concerning the use of a precusor drug (4-MA; a 5-alpha reductase inhibitor) in preventing male pattern baldness in macaques (animal model for male pattern baldness in humans). The study was 20 months in length. As it takes about 6 months to 1 year after a paper is submitted until it gets published and Merck had to spend some time planning and writing the paper (a few months to a year), the scientists at Merck were clearly thinking about the use of 5-alpha reductase inhibitors in the early to mid 1980s. As finasteride was patented in 1984 (or about this time) and approved for used in BPH in 1992, its use in humans would not have occured in clinical trials until the late 1980's. In other words, the potential utility of 5-alpha reductase inhibitors in male pattern baldness was being discussed at Merck before a human ever took finasteride.

Finasteride was origninally designed to treat both BPH and male pattern baldness, and the proof is in the literature; it was NOT found by 'accident' to be of value in male pattern baldness in patients originally treated for BPH. In the landmark paper on inherited 5-alpha reductase deficency, Imperato-McGinley et al (Imperato-McGinley et al., Steroid 5-alpha reductase deficency in man: an inherited form of male pseudohermaphroditism, Science, 186, 1213-1215, 1974) noted that men with this disease don't develop prostate problems and don't lose their hair. You can see the Merck researchers seeing this and thinking they can make more money if they design a single drug to treat both conditions, which is what they did. In their paper from 1987 (Rittmaster et al, The Effects of N,N-Dimethyl-4-Methyl-3-Oxo-4-Aza-5- alpha Androstane- 17beta- Carboxanide, a 5-alpha Reductase Inhibitor and Antiandrogen, on the Development of Baldness in the Stumptail Macaque. J. Clin. Endo. Met., 65, 188-193), they studied the value of using a precursor to finasteride (abbreviated 4-MA) in treating male pattern baldness in the macaque, a model for human male pattern baldness. How does this prove that finasteride was also designed to treat male pattern baldness? The study was submitted in January, 1987 and was a 27-month study of the macaques. Thus at the very latest Merck researchers were thinking about the use of a 5-alpha reductase inhibitor in male pattern baldness in late 1984. This doesn't account for the planning done to create the study, demonstrating that Merck was thinking about the use of a 5-alpha Reductase Inhibitor in male pattern baldness from the early to mid 1980's, long before finasteride was ever synthesized.

 

[otis]

Sorry to disagree but that is not put out by Merk. It is nothing more than hearsay.

 

[Bryan]

Sorry to disagree but that is not put out by Merk. It is nothing more than hearsay.

ROTFLMAO!! You've just given me the biggest laugh I've had all day! You just keep right on believing that finasteride for hairloss was an "accidental discovery"! :laugh: :laugh: :laugh:

 

[nohawk]

I was interested in this topic before the two baldies started beefing... :thumbdown2:

 

[tinytim30]

hi bryan i did not want to restart another post but have you tried ru58841m or have you wanted to try it,and also is that right that rum should be used with a regrowth agent such as minoxidil.