Serotonin, DHT and testosterone questions

tomsmith

Established Member
Reaction score
0
The last few weeks I've been looking outside of the scope of DHT and looking at the relationship between testosterone and other hormones, enzymes e.t.c.

A few months back, for no reason that I can be sure of, my beard began growing faster, oily skin and scalp occurred and my hair thinned everywhere (I've never had thinning at all). It felt like my body had just decided to up my testosterone levels out of the blue. I'm 24.

Naturally I assumed that Propecia (on since 21) could not deal with this and moved to Dutasteride. The problem is, if I can't figure out how to get my body back to the condition it was in before I have a serious problem.

I was under the impression that low testosterone, for someone in my position, was a good thing.

However, am I right in thinking that lower testosterone directly affects serotonin levels? If so would lowered serotonin cause the thyroid to slower metabolism and thus increase the chance of hairloss and tiredness?

It seems like a direct contradiction to what I feel is happening to me. The entire 3 years I was on Propecia I had no sex drive, regular spells of misery, slow beard growth, dry skin, was always tired and had no further hair loss. My testosterone level at least seemed like it was very low.

Or was it because I had lowered DHT? I thought DHT had no direct relationship with facial hair? Confusing!

Did Merck actually research testosterone levels during (after 2 years) Propecia trials? For example, I know that less of it binds with DHT so there is more available, but could the body (from my point of view) overcompensate in some way?

If anyone can shed any light I'd appreciate it.
 

Bryan

Senior Member
Staff member
Reaction score
42
tomsmith said:
Or was it because I had lowered DHT? I thought DHT had no direct relationship with facial hair? Confusing!

Huh? DHT almost certainly stimulates the growth of facial hair.

tomsmith said:
Did Merck actually research testosterone levels during (after 2 years) Propecia trials? For example, I know that less of it binds with DHT so there is more available...

I assume that what you meant to say is that testosterone goes up when you take Propecia because less of it is being converted to DHT. But that's a little bit misleading. Testosterone probably increases because its production is actually being upregulated. DHT is a player in the feedback control of androgen production, so when the brain "sees" less DHT around, it sends the hormonal signals to make more testosterone as a response.

Bryan
 

maddoc23

Established Member
Reaction score
0
Tom,

Sounds like you were depressed during that time. Lots of people have adjustment disorders with depressed moods after traumatic events happen. For example, if you lost both your legs tomorrow you would be feeling pretty down. Don't know if you thyoid is causing any problems. Best way to guess is by looking at your family history and also if you have any other autoimmune diseases such as Diabetes Mellitus Type I, addisons disease, celiac disease etc.

D
 
Top