Started Micro Dosing finasteride Today, Tracking Results

[Alk]

Ill be posting my experience for the greater good. I started micro dosing today. I dissolved a generic finasteride tablet (1.25mg) cut from the 5mg into 50ml of everclear and will be taking .015 mg eod untill thursday. Then .02 mg for another week eod and then increasing to .01 every two weeks until i reach .05 and stay around there for a couple of months. Took base pics but ill hold on to them for now and ill report back here every uped dose and then maybe monthly.


My generic finasteride is teva

When i get to .05 ml of finasteride ill take the whole tablet and dissolve it into the 50ml solution and take half a ml. If anyone does microdosing remember to keep the solution out of direct sunlight.

 

[jb5]

Good luck, i'll be watching your progress! I get sides (brain fog / libido) on 1.25mg per night. I'm only taking it every 2/3 nights now and not so bad, still think my libido is a bit low. So I will also be trying to find a dosage that can work for me without sides.

 

[Afro_Vacancy]

Good luck, looking forward to hearing your progress.

 

[horunger]

Wouldnt nanodosing be a better name for it? Its an interesting experiment but i must say i have serious problems understanding why youre doing it, if youre THAT afraid of finasteride sides you shouldnt be using it at all. What good can you possibly expect from so low dosaging?

 

[horunger]

Good luck, i'll be watching your progress! I get sides (brain fog / libido) on 1.25mg per night. I'm only taking it every 2/3 nights now and not so bad, still think my libido is a bit low. So I will also be trying to find a dosage that can work for me without sides.

Has the reduced dose reduced your sides, or has time reduced it? Have you already increased the dose back up and then down again, and in doing so sucessfully recreated the rise and fall in side effects? finasteride and dutasteride sides are reduced with time, you should assume thats what happened to you too.

 

[shulk]

i have serious problems understanding why youre doing it

One could start with micro dosing to:
1. Possibly lower the chance of getting side effects
2. Reduce the severeness of possible side effects
3. Ween on (see if you get any side effects, and if you don't gradually up the dose with more confidence.)

If you research over the internet it seems that some people get away with a lower dosage/inhibition rate whilst others don't. By going on full right away you deny the possibility of belonging to the first. Some people are in a bad spot though and don't have the luxury of time to tinker around with small dosages. That is totally understandable.

 

[horunger]

For 1 and 2 ask the questions i asked jb5 above. Time heals a lot of sides but rarely gets the credit for it, if the side increase and decrease cannot be recreated its not scientifically sound. Remember, you would have to do an increased dose for at least 3 months to rule out time being the main reason for the reduction in sides.

By applying stricter standards to my own subjectivity i have determined that the testicle pain i had when starting finasteride was time limited and not much dose dependent. The reduction in sperm volume was permanent and seemingly not dependent on either.

 

[stachu]

I think its completly useless, .015mg you will get rid of this on first pee and i dont think so, your body will actually react.

But hey! Good luck. Will follow thread somehow.

 

[horunger]

I think its completly useless, .015mg you will get rid of this on first pee and i dont think so, your body will actually react.

But hey! Good luck. Will follow thread somehow.

I have to agree, dividing a 5mg into 8 is already micro-dosing imo, but dividing it into 333 doses, thats mindblowingly low. What possible effect can there be, i bet i had higher concentration in the blood a month after i quit fina.

Edit: oh fukk, 5mg single dose and a halflife of 6 hours means in simplified (naive) theory it would take almost 3 months to reach a relative level of 0.015... ofcourse that is a naive model but shows that the dosage is seriously low.

 

[Alk]

Wouldnt nanodosing be a better name for it? Its an interesting experiment but i must say i have serious problems understanding why youre doing it, if youre THAT afraid of finasteride sides you shouldnt be using it at all. What good can you possibly expect from so low dosaging?

Wouldn't call it fear more like understanding

There's a graph and a studys showing .05 almost as effective as .2, 1 and 5mg. It also shows that scalp dht is also very close between doses but .05 has the smallest effect on serum. Seeing as .05 is amost as effective as 1mg then between .02 and .05 is really the only time to ween in. And although the half life of finasteride is 6 hours it irreversibly binds to 5 ar so it would still take days to weeks for dht to return to normal hence I think eod will do fine. If i want to take this for a extended period of time and i do not get sides and halt loss at .05 then the rest of the dose is unnessasry relieving my liver of some work. It also leaves room for small increases although the difference will be debatable.

So the effect of .05 or any microdose below .25 definetly has effect without a doubt but it has been proven that 1mg is a "safe" and recommended dose


I feel that weening on and off when starting or stopping treatment could help reduce sides

 

[Afro_Vacancy]

Wouldnt nanodosing be a better name for it? Its an interesting experiment but i must say i have serious problems understanding why youre doing it, if youre THAT afraid of finasteride sides you shouldnt be using it at all. What good can you possibly expect from so low dosaging?

No.

"Centi-dosing" would actually be the better name if you want to be a pedant, as he's taking approximately one hundredth of a standard dose.

"Nanodosing" would be 0.000000001 mg/day would be nano-dosing.

But I think the term microdosing is used colloquially for any small dose that is above the homeopathic range. For finasteride, the dose response is different in the 0.01-0.05 mg/day range, approximately, so that's the appropriate range.

 

[horunger]

Wouldn't call it fear more like understanding

There's a graph and a studys showing .05 almost as effective as .2, 1 and 5mg. It also shows that scalp dht is also very close between doses but .05 has the smallest effect on serum. Seeing as .05 is amost as effective as 1mg then between .02 and .05 is really the only time to ween in. And although the half life of finasteride is 6 hours it irreversibly binds to 5 ar so it would still take days to weeks for dht to return to normal hence I think eod will do fine. If i want to take this for a extended period of time and i do not get sides and halt loss at .05 then the rest of the dose is unnessasry relieving my liver of some work. It also leaves room for small increases although the difference will be debatable.

So the effect of .05 or any microdose below .25 definetly has effect without a doubt but it has been proven that 1mg is a "safe" and recommended dose


I feel that weening on and off when starting or stopping treatment could help reduce sides

That "understanding" does not include understanding of the data behind the graph. Its an average of mixed results from people with wildly different results, what makes you think its a great idea to put yourself smack in the middle of the statistics? Or, why does shoes have sizes if we are all so similar that individuality can be disregarded? Dont forget that statistics will include persons with no results from 5mg and others with great results from 0.05, and then to add more complexity theres those who see increased DHT levels from fina, you cant see them but theyre in the data collection too, maybe youre even one of them, how can your graph predict that?

 

[Alk]

That "understanding" does not include understanding of the data behind the graph. Its an average of mixed results from people with wildly different results, what makes you think its a great idea to put yourself smack in the middle of the statistics? Or, why does shoes have sizes if we are all so similar that individuality can be disregarded? Dont forget that statistics will include persons with no results from 5mg and others with great results from 0.05, and then to add more complexity theres those who see increased DHT levels from fina, you cant see them but theyre in the data collection too, maybe youre even one of them, how can your graph predict that?

Yes there is shoe sizes but i know mine. I dont know my finasteride dose hence the trying of low to high. I get the graph, thanks thou, they are averages but averages of its effectiveness. The study just concludes my thoughts. And yes the study may show no resilts but dht is effected in all cases. And no noones dht rises from finasteride their receptors are most likely up regulated. Ill try and find it so you can better understand.

The graph doest predict it just shows results and im trying to see where i fit in the situation.

 

[horunger]

How about this understanding for a fact, most people tolerate 0.5 dutasteride very well and the results are good with a fairly low chance of unending shedding. Safe dose, best results, average its just great even at 0.1 dose. I think you two dont care about results from whats already been established as a safe dose. I risk having to eat my words later on but dutasteride so far has less sides for me than a small dose finasteride had.

 

[Afro_Vacancy]

How about this understanding for a fact, most people tolerate 0.5 dutasteride very well and the results are good with a fairly low chance of unending shedding. Safe dose, best results, average its just great even at 0.1 dose. I think you two dont care about results from whats already been established as a safe dose. I risk having to eat my words later on but dutasteride so far has less sides for me than a small dose finasteride had.

Of course we care about results. Everybody cares about results.

As for dutasteride, I've mentioned that previously several times. It's an oddity, but the drug which is substantially more powerful (dutasteride) appears to cause fewer side effects both officially and anecdotally.

But that's aside from finasteride microdosing, which is being pursued by an actual company called polichem. When you lower the dose far enough, to ~0.03 mg/day, you get DHT inhibition in the scalp but not in the serum. That's a different domain that might be even safer.

 

[Alk]

How about this understanding for a fact, most people tolerate 0.5 dutasteride very well and the results are good with a fairly low chance of unending shedding. Safe dose, best results, average its just great even at 0.1 dose. I think you two dont care about results from whats already been established as a safe dose. I risk having to eat my words later on but dutasteride so far has less sides for me than a small dose finasteride had.

The problem with dutasteride is it inhibits 5 ar 1 and im not willing to do that but it is effective at low doses because it is so much more potent than finasteride and the half life is nearly one hundred times as long. I think dutasteride is seen as having less sides because there is not as many people on it and its not approved by the fda for hairloss so information is lacking. All studies ive read show similiar accounts of sides from finasteride and dutasteride. But sides are just a calculated risk and it its working for you keep at it. And again there is results when micro dosing finasteride, ill have to wait and see myself.

 

[Alk]

I found the graph and chart, ill be looking for the actual studies next. Tomorrow I will increase my dose to 0.03 instead of 0.02 because I feel it's very close to placebo.

 

[Alk]

This shows imapct on scalp dht as low as 0.01 mg of finasteride

 

[Mahalo]

Great thread and good luck with this, i have always been tempted to try 0.025mg of propecia by dissolving a 1mg tablet in a 40ml miniature of the strongest vodka i can find here in the UK and taking 1ml every 3 days or even just once a week (probably a bit too cautious!). Keep us updated! Have you ever had any bloodwork done measuring your pre propecia dht levels?

 

[horunger]

Of course we care about results. Everybody cares about results.

As for dutasteride, I've mentioned that previously several times. It's an oddity, but the drug which is substantially more powerful (dutasteride) appears to cause fewer side effects both officially and anecdotally.

But that's aside from finasteride microdosing, which is being pursued by an actual company called polichem. When you lower the dose far enough, to ~0.03 mg/day, you get DHT inhibition in the scalp but not in the serum. That's a different domain that might be even safer.

Do you believe we will see people with excellent hair retention after doing finn microdosing for 5 or 10 years? Even on 5mg, anyone with full hair after 10 years? If the scalp inhibition is so good why do people keep thinning, could it be that scalp inhibition is not enough... if it was enough we would all be hairy as a Shi-Tzu, instead we all head on the fast track to looking like a Chinese Crested. Obviously the success chances on finn microdosing is that of an icecube getting a tan on the beach.