Stemson is going to use minipigs in the next stage of their hair cloning research

[werefckd]

comments from another video

https://imgur.com/a/tQdfGbB

 

[badnewsbearer]

low how they have to wct as if malr pwttern bsldness ie the most minor issues and they are really doing it to the ppor womenzz who get alopecia areata or chemo therapy, male pattern baldness is JUST an inconvenience. if it was women whos appearance just got degenerated at 20 purely based on luvk itd be a different story

 

[badnewsbearer]

what i like is their idea of using their platform and cell cuktures to learn more about the condition snd develop topivals to address certain issues as well. it seems they are now in the midst of pig trials and if they are more confident they will raise a B round and go into human trials.

 

[trialAcc]

low how they have to wct as if malr pwttern bsldness ie the most minor issues and they are really doing it to the ppor womenzz who get alopecia areata or chemo therapy, male pattern baldness is JUST an inconvenience. if it was women whos appearance just got degenerated at 20 purely based on luvk itd be a different story

They do it for marketing purposes. If it's not obvious by now, people in general dont care about male pattern baldness. If you add women & people with other serious conditions to the treatment target base you get a lot more attention, as women are actually just as large of a market size as men when it comes to thinning hair, they just don't lose it entirely in most cases so it doesn't seem as obvious.

 

[badnewsbearer]

They do it for marketing purposes. If it's not obvious by now, people in general dont care about male pattern baldness. If you add women to the treatment target base you get a lot more attention.

so whx make a product at all? they coule be doing spinal cord treatment with IPC but they chose to focus on this issue that mostly affects men. i think their attrmpts to cure scarring alopecia or areata is even hsrder because with androgenic slopecia you just havr to address the sndrogen sensitivity problem, with other cinditions you havr auto immune issues to address so the cloned hair doesnt just fall out. where is there money coming from?

 

[trialAcc]

The presentation was actually pretty good. The fact that they mentioned a series B on the deck in relation to human trials hints that it's not that far away. Maybe in late 2022 or H1 2023 we see that announcement and they move towards trials.

 

[trialAcc]

so whx make a product at all? they coule be doing spinal cord treatment with IPC but they chose to focus on this issue that mostly affects men. i think their attrmpts to cure scarring alopecia or areata is even hsrder because with androgenic slopecia you just havr to address the sndrogen sensitivity problem, with other cinditions you havr auto immune issues to address so the cloned hair doesnt just fall out. where is there money coming from?

I don't have time to explain to you how the venture capital game works, but in short, the larger the market size you are targeting the better your odds of getting attention, scale and funding.

The CEO said it himself, this is a self funded market and they need to develop products with that caveat in mind. He basically just described the entire reason we don't have a hairloss cure available today, yet people routinely still ignore it. There is no money in treating hairloss & most people cant drop tens of thousands for hair.

 

[pegasus2]

Interesting presentation. Shame no one had any questions. It sounds like they've already had success in pig trials and think they will be ready for human trials soon. That's a lot more optimistic than what we last heard from them. I'm glad they are going with the autologous approach first, as that will be easier to get approved and I'd prefer that anyway.

 

[trialAcc]

Interesting presentation. Shame no one had any questions. It sounds like they've already had success in pig trials and think they will be ready for human trials soon. That's a lot more optimistic than what we last heard from them. I'm glad they are going with the autologous approach first, as that will be easier to get approved and I'd prefer that anyway.

I agree. The only thing that disappointed me in this video was when he said they were talking to industry partners in robotics. That basically means they are talking to ARTAS and I don't think anyone should want one of those existing things touching their heads. That's not to say they wont be getting more advanced systems in place, but I thought they were doing the technology in-house.

 

[badnewsbearer]

I agree. The only thing that disappointed me in this video was when he said they were talking to industry partners in robotics. That basically means they are talking to ARTAS and I don't think anyone should want one of those existing things touching their heads. That's not to say they wont be getting more advanced systems in place, but I thought they were doing the technology in-house.

i mean you can do an artist job at the hairline and artas at the crown and nobody is fonna notice and it will be aestetically pleasing. people have ridiculous standards, i realized this when people talk about densitity and whether they csn get this and that density natural density blablabla, who gibes a f***, all the matter is to have a decent amount of coverage and a natural hairline

 

[Raccooner]

so whx make a product at all? they coule be doing spinal cord treatment with IPC but they chose to focus on this issue that mostly affects men. i think their attrmpts to cure scarring alopecia or areata is even hsrder because with androgenic slopecia you just havr to address the sndrogen sensitivity problem, with other cinditions you havr auto immune issues to address so the cloned hair doesnt just fall out. where is there money coming from?

Regarding the pattern baldness issue: You forgot the other problem, which is skull expansion, being a reason many men and some women lose their hair. As we grow older, strangely our skulls continue to grow (for whatever reason). It seems the best remedy for this at the moment is hormone replacement therapy. Males who transition to females, the skull changes shape slightly (shrinkage) along with other hormonal changes and magically the hairline returns in many cases. The real cure might be doing this to prevent unwanted physiologic changes and getting de novo hair follicles implanted if hair doesn't return. I would have no problem changing sex, but the problem is not being able to reproduce, increased cancer risk, awkward transition period and adapting to the new changes. Of course, there's the pressures of society in doing this and whether or not there will be acceptance or rejection from employers, friends and family. For those wishing to stay men and get the hair back permanently, I really don't see how this is a possibility. Heck, even Finasteride and Dutasteride are potentially feminizing and often cause permanent sexual impotence. So what to do with the hormonal issue needs to be figured out first in this battle. Most men want to stay men but how is it possible to do without eventual hair miniaturization or how to inhibit the 5AR from converting testosterone into DHT without taking away male reproductive sex abilities? Yes, so this is being done in reverse. It is the hormonal issue that needs to be worked out first and then the hair cloning if hair won't return after the hormonal issues have been worked out in individuals.

For autoimmune conditions, yes, that must be worked out first before hair will be able to survive once implanted. This alone can take years to get worked out for people if at all.

For scarring alopecia that is burnt out or happened through traumatic ends this hair cloning idea makes sense, but the skin surface has to be in good shape for the implants to take and grow.

In order words this hair cloning is going to be a cure for some people but for many others it won't be a long-term solution as the hair shrinkage and hair destruction problem will continue without other needed interventions first.

 

[Raccooner]

You lost me at skull

Skull Expansion Theory for Hair Loss by Paul Taylor (hairgrowthsos.com)

 

[trialAcc]

Regarding the pattern baldness issue: You forgot the other problem, which is skull expansion, being a reason many men and some women lose their hair. As we grow older, strangely our skulls continue to grow (for whatever reason). It seems the best remedy for this at the moment is hormone replacement therapy. Males who transition to females, the skull changes shape slightly (shrinkage) along with other hormonal changes and magically the hairline returns in many cases. The real cure might be doing this to prevent unwanted physiologic changes and getting de novo hair follicles implanted if hair doesn't return. I would have no problem changing sex, but the problem is not being able to reproduce, increased cancer risk, awkward transition period and adapting to the new changes. Of course, there's the pressures of society in doing this and whether or not there will be acceptance or rejection from employers, friends and family. For those wishing to stay men and get the hair back permanently, I really don't see how this is a possibility. Heck, even Finasteride and Dutasteride are potentially feminizing and often cause permanent sexual impotence. So what to do with the hormonal issue needs to be figured out first in this battle. Most men want to stay men but how is it possible to do without eventual hair miniaturization or how to inhibit the 5AR from converting testosterone into DHT without taking away male reproductive sex abilities? Yes, so this is being done in reverse. It is the hormonal issue that needs to be worked out first and then the hair cloning if hair won't return after the hormonal issues have been worked out in individuals.

For autoimmune conditions, yes, that must be worked out first before hair will be able to survive once implanted. This alone can take years to get worked out for people if at all.

For scarring alopecia that is burnt out or happened through traumatic ends this hair cloning idea makes sense, but the skin surface has to be in good shape for the implants to take and grow.

In order words this hair cloning is going to be a cure for some people but for many others it won't be a long-term solution as the hair shrinkage and hair destruction problem will continue without other needed interventions first.

Bro, what the f*** are you talking about.

 

[Raccooner]

Bro, what the f*** are you talking about

What specifically would you like me to clarify?

 

[Joxy]

So, like I understand they already tested the technology on pigs and it is working pretty well?

 

[Joxy]

Interesting presentation. Shame no one had any questions. It sounds like they've already had success in pig trials and think they will be ready for human trials soon. That's a lot more optimistic than what we last heard from them. I'm glad they are going with the autologous approach first, as that will be easier to get approved and I'd prefer that anyway.

Like I understand from video presentation they already tested the technology on pigs and have high confidence that this will work on humans. Correct me if I am wrong.

 

[badnewsbearer]

Like I understand from video presentation they already tested the technology on pigs and have high confidence that this will work on humans. Correct me if I am wrong.

they testes kn pigs but not high confixenxe yet, they said once they do have high confidenxe they will do a B funding and woek towards trials

 

[coolio]

What specifically would you like me to clarify?

Skull expansion = hair loss? Come on.

It's a longstanding theory and it's never had scientific support. Just elaborate ideas built out of correlations.

 

[Raccooner]

Skull expansion = hair loss? Come on.

It's a longstanding theory and it's never had scientific support. Just elaborate ideas built out of correlations.

I think the argument makes plenty of sense. Tight scalp due to the skull's expansion leads to constriction of the capillaries which are needed to supply blood to the follicles. If this is bogus then how is it that in trans women the skull shape remodels, shrinks in shape or size and miraculously the hairline often returns? The only other argument would be hormonal change. Getting the needed blood supply to the hair follicles is crucial to their thickness and long-term survival. If you still think what I am telling you is theoretical bull, then tell me please. What causes pattern hair loss to occur?

 

[losingbattle88]

I dont know about you guys but I want a mini pig now..