Topical Dutasteride Case Assessment Thread

fadedsun88

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I stamp once a week 1.5mm then directly after apply 5mg dutasteride which for me is 10ml. the other days of the week I use oral dutasteride instead because using 5ml or even 10ml topically each day of the week would empty my bottles in no time. do you apply your solution directly after derma stamping? 1ml for you is 5mg. ok so if you want to use more ML to cover your scalp I would have taken 1ml from your solution then put it in another tiny bottle and then add a few ml of something else like minoxidil or grain alcohol this way you have enough ML to cover the scalp and you will still have 5mg of duta on the scalp just more evenly spread out.
Thanks man.

Right now I am applying .5ml which is around 2.5g of dutasteride in the combi with a glove on my vertex where I have the most loss right after showering. After this i take a 1.5mm dermpen Dr.Pen, and go across the vertex, it gets red but doesnt bleed. I have been doing the stamping around 4 consecutive weeks rn and I feel no change in my body as far as libido or nipple pain etc. My thought is not a lot of dutasteride is going systemic despite the needling. I apply the combo every day after showring before bed 6 days a week without needling and on the 7th day ill needle. Hoping to see some results by june/ july. everything is documented via photos in same and different lighting so I can post here. Hoping to limit sides as a result of this too. Ill prob continue this for a few more weeks then taper off to help with dutasteride build up.

Side effects on scalp so far have been (could be related or unrealted to treatment idk):
increaed hair loss
more diffuse thinning all over
lots of dandruff which I have never had before
scalp tingling, and pain sometimes
scalp generally feels kinda unhealthy but maybe this is the break in period. it has only been 6 weeks


will keep you guys updated.
 

fadedsun88

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I did 4ml of 0.5% again and DHT dropped to 160 ng/dl from 330 ng/dl, pretty much 50% serum reduction.

No drop at 0.1% so I'm going to try 0.05% now daily or every other day tops to keep stable DHT scalp levels and hopefully serum DHT will remain intact as it did with 0.1%

Anybody else using CB? I am thinking of making a single bottle with CB 7.5%, Dutasteride 0.01%, Latanoprost 0.005% and Minoxidil 7%. This would be very convenient to apply once a day and have everything covered for androgens and stimulating growth as well as thickening.
You mentioned Mesotherapy before via dermneedling. Do you think this is just as effective? The Dutasteride in mesotherapy 0.01% 1-2ml needs to be sterile and they inject it into the dermis kinda causing little boluses. We are applying topically and dermneedling 1.5mm, was curious to hear your thoughts. I really was considering doing this at one point.
 

Mustang

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You mentioned Mesotherapy before via dermneedling. Do you think this is just as effective? The Dutasteride in mesotherapy 0.01% 1-2ml needs to be sterile and they inject it into the dermis kinda causing little boluses. We are applying topically and dermneedling 1.5mm, was curious to hear your thoughts. I really was considering doing this at one point.

The only difference is 2mm vs 3mm with the injection. It's has effective in my opinion. When I went to the best clinic in Spain to perform it they used a Dermapen at 2mm and they have great results. If it's injection then you require sterile water, if it's dermapen then you don't.

I am not currently using it but it's quite drastic in terms of regrowth. I am sure all the other stuff in the formula has an impact as well, there are some studies on it online
 

fadedsun88

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The only difference is 2mm vs 3mm with the injection. It's has effective in my opinion. When I went to the best clinic in Spain to perform it they used a Dermapen at 2mm and they have great results. If it's injection then you require sterile water, if it's dermapen then you don't.

I am not currently using it but it's quite drastic in terms of regrowth. I am sure all the other stuff in the formula has an impact as well, there are some studies on it online
did you go to the clinic in Madrid?
 

fadedsun88

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wow good to know, because i was under the impresssion they were using injections. worse case i’ll just get a solution compounded for me of pure dutasteride at 0.01% and derm pen at 3mm once a month see what happens!
 

losingbattle88

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Thanks man.

Right now I am applying .5ml which is around 2.5g of dutasteride in the combi with a glove on my vertex where I have the most loss right after showering. After this i take a 1.5mm dermpen Dr.Pen, and go across the vertex, it gets red but doesnt bleed. I have been doing the stamping around 4 consecutive weeks rn and I feel no change in my body as far as libido or nipple pain etc. My thought is not a lot of dutasteride is going systemic despite the needling. I apply the combo every day after showring before bed 6 days a week without needling and on the 7th day ill needle. Hoping to see some results by june/ july. everything is documented via photos in same and different lighting so I can post here. Hoping to limit sides as a result of this too. Ill prob continue this for a few more weeks then taper off to help with dutasteride build up.

Side effects on scalp so far have been (could be related or unrealted to treatment idk):
increaed hair loss
more diffuse thinning all over
lots of dandruff which I have never had before
scalp tingling, and pain sometimes
scalp generally feels kinda unhealthy but maybe this is the break in period. it has only been 6 weeks


will keep you guys updated.
hmm I dont use dr pen I use a normal dermastamp and I press as hard as I can so the whole 1.5 needle penetrates into the skin and I do this all over my head and dont miss a spot because I got diffuse thinning and receeding. but I do get red spots of blood all over. im too afraid to go over 1.5mm because of fear of causing scarring or hitting a hair folicle and killing it. also if u use 2mm you have to wait longer than a week to stamp again it needs to heal longer because the hole is deeper you know this already but 1.5mm isnt bad once a week. but I take duta orally too so its not very needed to use duta on scalp often or go deep with stamping.
 
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losingbattle88

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please, less theory, more experiments. i use 1% in 2x3ml ED (60mg/day). it makes me a numbskull (no scalp itch) until the next dose (6am to 10pm). i have 40% ethanol in my mix. i make a new batch every week.
wow that sounds great. do you buy the tablets and crush them yourself or what? how about taking the pills orally too....
 

trialAcc

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Why do you think topical duta will help you much when oral finasteride+dutasteride has failed you? you even take it x1 week. take it everyday instead bro.
I dropped dutasteride 1x weekly after 6~ weeks because I started having sides consistent with reflex hyperandrogenicity after taking it. Of course it could have been the increase in T, but the scalp itch/oil/acne and insane shedding seems consistent with what people describe to be RHA and it's still present 2-3 months later.

Trying to lessen the systematic effects while upping the local ones. Oral finasteride also didn't fail me, it worked for 6~ years prior to the forced break.
 

fadedsun88

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I dropped dutasteride 1x weekly after 6~ weeks because I started having sides consistent with reflex hyperandrogenicity after taking it. Trying to lessen the systematic effects while upping the local ones.
What dose? if i were to start oral dutasteride it would be 0.5mg/2.5mg of minoxidil once a week and work my way up from there
 

trialAcc

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What dose? if i were to start oral dutasteride it would be 0.5mg/2.5mg of minoxidil once a week and work my way up from there
0.5mg 1x weekly. I don't have proof that it was the dutasteride though. Could have been the topical finasteride I briefly tried or just when I restarted taking finasteride after 3~ months off.
 

losingbattle88

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0.5mg 1x weekly. I don't have proof that it was the dutasteride though. Could have been the topical finasteride I briefly tried or just when I restarted taking finasteride after 3~ months off.
oh I see thanks for telling us.
 

trialAcc

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oh I see....u make me abit worried now because I have been on oral duta for 2 months and topical for almost 2 months but took a break for 2-3 weeks with topical application due to not enough liquid, so kept using oral instead now im back on topical once weekly and oral dutasteride everyday. I dont feel any reflex hyperandrogenicity to be honest... my shedding has calmed down now after shedding more before thankfully. but I also had quit minoxidill after 5 months of usage so it could have been that too or the duta I dont know. but what type of side effects did you notice please tell me so I know what to look for.
Insane shedding + minor scalp oil increase, coupled with the insane scalp itch & scalp acne/redness where I'm losing hair. I've dropped about a Norwood (from 2 to 3v) in about 6-7 months. No increase of libido though, which seems to be the staple of RHA.

Again, not sure if it's RHA or just catch up loss, playing with treatments, etc, but something is wrong. If topical dutasteride is effective I will drop oral finasteride all together and hope the RHA/loss halts or normalizes.
 

losingbattle88

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Insane shedding + minor scalp oil increase, coupled with the insane scalp itch & scalp acne/redness where I'm losing hair. I've dropped about a Norwood (from 2 to 3v) in about 6-7 months. No increase of libido though, which seems to be the staple of RHA.

Again, not sure if it's RHA or just catch up loss, playing with treatments, etc, but something is wrong. If topical dutasteride is effective I will drop oral finasteride all together and hope the RHA/loss halts or normalizes.
well you are aware that topical dutasteride will increase scalp T like oral does. only pharmacy I know that is close to you is from US. I live in sweden and it takes 3 weeks to get my sh*t from US. so for you definately less time. but I truely hate to pay 46 bux in custom fees. so I end up paying alot for my products.
 
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trialAcc

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well you are aware that topical dutasteride will increase scalp T like oral does. only pharmacy I know that is close to you is from US. I live in sweden and it takes 3 weeks to get my sh*t from US. so for you definately less time.
The fact that these issues still remain despite not taking any dutasteride for almost 3 months tells me that it probably isn't the increase in T. Any dutasteride should be out of my system by now, I would assume?

I'm going to try topical dutasteride and drop my oral finasteride dose to 1x weekly. If that fails I will either have to accept the bald and quit it all or just take an extended finasteride break to normalize my system and try again in 6-9 months. I've actually already come to terms with the hairloss even though id rather hope for continued maintenance, but if I have to let it go, it is what it is. It's the uncomfortable feeling and scalp itch that's really starting to bother me.
 
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losingbattle88

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The fact that these issues still remain despite not taking any dutasteride for almost 3 months tells me that it probably isn't the increase in T. Any dutasteride should be out of my system by now, I would assume?

I'm going to try topical dutasteride and drop my oral finasteride dose to 1x weekly. If that fails I will either have to accept the bald and quit it all or just take an extended finasteride break to normalize my system and try again in 6-9 months. I've actually already come to terms with the hairloss even though id rather hope for continued maintenance, but if I have to let it go, it is what it is. It's the uncomfortable feeling and scalp itch that's really starting to bother me.

when I use keto shampoo it dries my scalp and cause more tingling and itch if ur using that drop it. but sounds like a plan good luck to you my brother in arms.
 
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