Topical Dutasteride Case Assessment Thread

[losingbattle88]

no luck with topical/oral duta as of yet 3 months in no change to hair or thickening or reduction in hairfall. losing many thick short hairs and some thin ones.

PS: if I would take 1mg-2mg of duta orally daily would there be any point to use it topically too? I think it would just cause hormonal imbalance this way since topical also goes systemic abit. last time I used 5mg topically with 1.5 derma stamp I had alot of pain in both of my nipples that lasted a few hours. never any pain when taking dutasteride orally ED or EOD. So I know that the scalp absorbed at least 4mg dutasteride into my system and it turned into estrogen thus causing nipple pain. the only side effect I have from dutasteride is that my sperm dont wanna shoot out anymore it pretty much just oozes out. this is due to lower production of sperm OR the dutasteride has shrunken my prostate so much that it lacks the force to shoot the sperm out. im no doctor but it has something to do with lower sperm production and the prostate.

 

[TanDoc]

no luck with topical/oral duta as of yet 3 months in no change to hair or thickening or reduction in hairfall. losing many thick short hairs and some thin ones.

PS: if I would take 1mg-2mg of duta orally daily would there be any point to use it topically too? I think it would just cause hormonal imbalance this way since topical also goes systemic abit. last time I used 5mg topically with 1.5 derma stamp I had alot of pain in both of my nipples that lasted a few hours. never any pain when taking dutasteride orally ED or EOD. So I know that the scalp absorbed at least 4mg dutasteride into my system and it turned into estrogen thus causing nipple pain. the only side effect I have from dutasteride is that my sperm dont wanna shoot out anymore it pretty much just oozes out. this is due to lower production of sperm OR the dutasteride has shrunken my prostate so much that it lacks the force to shoot the sperm out. im no doctor but it has something to do with lower sperm production and the prostate.

I would be skeptical of topical adding to effectiveness, when you're already taking that much systemically.

0.5 mg dutasteride daily reduces serum DHT levels by 84% at 2 weeks, by 90% at 1, 2, 3, and 4 months -

Effect of dutasteride on intraprostatic androgen levels in men with benign prostatic hyperplasia or prostate cancer - PubMed

The results of our study have shown that dutasteride provides near-maximal suppression of both serum and intraprostatic DHT levels in men with benign prostatic hyperplasia or prostate cancer at all points assessed.

pubmed.ncbi.nlm.nih.gov

Another study - the percent decrease in DHT was 98.4 ± 1.2% with 5.0 mg dutasteride and 94.7 ± 3.3% with 0.5 mg dutasteride, after 24 weeks (5 months)

https://academic.oup.com/jcem/article/89/5/2179/2844345

0.5mg daily is the standard medical dose for prostate hyperplasia (given to shrink the prostate if it has grown too large). Look at the data above - going from 0.5mg to 5mg only gets you 4% decrease in DHT. 1mg and 2mg are really not necessary for hair growth, and will give you more side effects than any increased results.

3 months is a little short to see results in hair. If you don't see changes at 6 months orally (even 0.5mg is killing 90-95% of DHT), DHT might not be the problem for you.

 

[FromHairy2LarryDavid]

Glad to see the number of ppl it seems to be helping. However, with the amount of feedback on dosages, frequencies, carriers, half life, mesotherapy etc - things got a bit messy along the way.

Is there anybody with enough experience to summarize the best way to use this treatment? (Preferably without minoxidil in their stack polarizing their views on sheds/gains etc)

I’m thinking of microdosing it weekly, right alongside my 1.5mm roller for mesotherapy. Just unsure of the proper dosage and half life of each specific solution/vehicle.

Some overall guidelines would certainly help before I - or others still hesitant - invest in any hormone tests, short half-life solutions, or topical AA’s for the local T rise along the hairline.

 

[TanDoc]

Glad to see the number of ppl it seems to be helping. However, with the amount of feedback on dosages, frequencies, carriers, half life, mesotherapy etc - things got a bit messy along the way.

Is there anybody with enough experience to summarize the best way to use this treatment? (Preferably without minoxidil in their stack polarizing their views on sheds/gains etc)

I’m thinking of microdosing it weekly, right alongside my 1.5mm roller for mesotherapy. Just unsure of the proper dosage and half life of each specific solution/vehicle.

Some overall guidelines would certainly help before I - or others still hesitant - invest in any hormone tests, short half-life solutions, or topical AA’s for the local T rise along the hairline.

There isn't really a good consensus yet unfortunately. We still only have a very small handful of success reports/pictures - could count on less than one hand the number of befores/afters I've seen attributed just to topical duta.

Lots of people have jumped on very recently - I feel like in several months there will be a ton of new reports on whether this is the breakthrough we've been looking for or not.

 

[TanDoc]

View attachment 159873View attachment 159874

now I'm confused. what is the criteria for a experiment that contributes to this thread?

I said I could count the number on less than one hand lol, of the number of success reports/pictures for topical duta.

Sonictemples posted an "after" picture (without a before), of a temple he said has regrowth.

Mustang had a picture of his crown filling in. He is the only one in this thread claiming "long term" success. His regimen (dosing) has varied even within the thread. He's also done a lot of other things though in the past (including multiple hair transplants, if I remember correctly).

Everyone else here is waiting to see more results or trying it themselves to (hopefully) post results soon. Over the next few months we're going to see a lot of new reports on this (hopefully successes).

 

[FromHairy2LarryDavid]

Sonictemples posted an "after" picture (without a before), of a temple he said has regrowth.

Which is my primary motivation to start it myself. Although it's beyond me how a testosterone rise was shown to severe the hairline, yet it's the very area sonic thrived in. Really a strange but promising treatment.

 

[sonictemples]

I said I could count the number on less than one hand lol, of the number of success reports/pictures for topical duta.

Sonictemples posted an "after" picture (without a before), of a temple he said has regrowth.

Mustang had a picture of his crown filling in. He is the only one in this thread claiming "long term" success. His regimen (dosing) has varied even within the thread. He's also done a lot of other things though in the past (including multiple hair transplants, if I remember correctly).

Everyone else here is waiting to see more results or trying it themselves to (hopefully) post results soon. Over the next few months we're going to see a lot of new reports on this (hopefully successes).

I do have a before picture on Discord

 

[losingbattle88]

I do have a before picture on Discord

you dont dermaroll or stamp is that correct? just rubb it in?

 

[sonictemples]

you dont dermaroll or stamp is that correct? just rubb it in?

Yes

 

[losingbattle88]

Yes

has minoxidill EOD been effective for you in any sort of way? it didnt grow your hairline back but did it retain it?

 

[Tazman2206]

Thanks for sharing your experience. Just to clarify, I have a few questions (apologies if you’ve already explained, but didn’t find anything) -

1) Do you mean full recovery of your hair loss or from side effects from your diy topical Dutasteride/ lipogaine?
2) If the former (of above), did you have any side effects from topical dutasteride?
3) What was/is your topical dutasteride dosage?
4) Did you switch to or add topical min/finasteride/RU? Why?

Thanks in advance

Hello,

1)Yes full recovery. But the right side had slightly thinner hair. 50/50 terminal / velous hair. But il looked fixed. It was UNBELIEVABLE. Especially I am 36 years old. So It's like I was a hyper responder. By the way the first month I had 2 session of derma roller. 0.25mm

2)Not really. But I felt weird if I took too much. ball ache and anxiety disappeared and I felt stronger. Not back to 100% but back to 90%

3)0.25 mg morning , 0.25 mg night. Once every other day . ( At the time I did not know about half life ...)

4)Because I watch a video of MPMD. Big mistake this idiot has no clue what he is talking about. (The side are so dangerous.....)
Why: because I thought that additional protection from testosterone would help my top right side which was slightly thinner


Just to clarify. I bought in 2017 a 1 year supply of finasteride tablet and Dutasteride. I was thinning but regrew all with aggressive massage Argan oil/Castor Oil/Pumpkin seed oil/Blak seed oil + Peppermint/Rosemary/Thyme/lavender. The massage had a preventative effect from 2005-till 2019.

After reading label of side effects on 2017 I never tried any drugs.. ( I so regret because If I had the knowledge I have now. My hair would still look amazing)...
By the way my 5 years younger brother went bald at 20 years old.. I kept my hair till 35-36


I did nothing from 2017 till 2020 for my hair loss. I though It had stop so stop my nightly massage routine.

This was stupid because if I knew today I would still haver a full head of hair.
What happen is that from July 2019 my hair started thinning ON/OFF progressively (No bald patch) so I did not see it coming until September 2020 when I was laying on my Bed at 12 noon and the sun was beaming. That when I realized with horror that the shedding that happened (July-september 2020) made some serious damage.

1)I first tried topical Minoxidil (Lipogaine) and re-started my oil massage.
Thiss had the effect to not only break my now thin hair but to made me shed even more.

2) By October 2020. I had a U horse shoe, Camel toe on my forehead. This was extremely stressful because I went from full head of thin hair at the top front to this horrible U pattern in a WEEK. All the base of the weak hair broke...

3) I tried in the beginning of October 2020. finasteride and Dutasterider tablet. for 2/3 week . This immediately gave me side (Anxiety, Pannick, Low mood tiredness, low energy, low sex drive, feeling of being worried) No side effect. MY ***. THIS IS THE BIGGEST LIE. The initial oral dose was 1mg finasteride. 0.5 mg dutasteride. I tried 2 week finasteride eod then dutasteride 3/4 days. Side effect were s0 bad I stopped.

4) I had various quote from turquey for Hair transplant but they sounded dodgy. So I kept the minoxidil and tried Dr lampazula. But this MF would not send me some liposomal solution.. ( I had found out about potential systemic effect of PG/ethanol)

5)As i did not want to flu to brussel for the medication or a hair transplant. At this stage I did a DIY solution. I empty 30 capsules of Advodart into my lipogaine minoxidil 5%. So 30 * 0.5mg = 15mg in 60 ml. Thats a 0.025% concentration. So if you take 1ml you get 0.25mg. If you take 2ml that 0.5mg. The idea was to apply morning and Night and not going above 0.5mg

6) from October to November 2020. The side did not increase as much unless I use a large dosage. But the shedding increase. At this stage 1st of November I shaved because I was looking horrible

7) From mid November I started to feel baby hair and then It went exponential. My hair grew at an incredible rate. The top left side had twice more terminal hair. The top right side had 50/50 terminal/ vellous hair.

8) I had ordered Just to try Topical Min/finasteride from minoxidil max because I was seduced by their formula 15% minoxidil/ 0.1% finasteride/Aelai acid..]
9) As soon as I received the RU I added the 3G of RU to the Topical finasteride around mid-December I started to fell itchiness and my hair started to shed again.


BY 10Th of December. I had recovered most of the first shed. No scalp was visible on the top Left side. Hair line was fixed on left side and top right side was slightly thinner.

Literally few day after adding the RU. My hair started to degrade and went through a SECOND SHED. By mid January I had 2 large coin shape bald patch. The left side was smaller than the right side..


I stopped the combo with RU. And revert to the topical Min/finasteride at night with Topical minoxidil foam...

We are now in March. All the mid top plus crown is amazing. the top left is very good. The mid top right is fucked. After the second shed hair starting falling and grew miniaturised and brittle on half of the top right side.

It almost like the RU shocked my hair and force them into a cobo of accelerated thinning and telogen not followed by an Anagen phase. (Horrible)


So I suspect two things could have happened.
1) the move from my DIY lipogaine\Duta to Mimoxidil max. The move from 5% to 15% concentration of Minoxidil could have shocked my Hair
2) Maybe the RU that I added literally fucked my hair. I suspect its RU because when I continued the 15%minoxidil/0.1%finasteride I had no itchiness/Burninhg

Dutasteride is stronger than Finasteride. So I don't suspect switching from Topical Duta to Topical finasteride triggered the shed....


Bottom Line. I believe one the two variable above messed me up. I recommend to not do my mistake and to not change routine especially if everything is working...


My Ultimate recommendation to any newbie is to learn from my success and avoid my stupid mistake and to follow the protocol below :


Please take a hormonal blood test before first application . 2 week after, 3 month after.

1) Morning topical foam minoxil 5% (Monday to Sunday)
2) Morning and Night 1 ml Liposomnal Dutasteride 0.025% ( So 0.25mg morning/ 0.25 mg Night). Once a week ONLY
3)Sunday Night 1.5mm micro-needling. and leave 24H before re-apply any product.


When I had the most gain. I had plenty of water, sleep,Biotin Vitaminc C (Liposomal) , Zinc/Copper. Iron Protein , Magnesium...
I am not sure vitamine did anything


ps: I invested in a Dr Pen M8. I made the top left side grew even thicker. But the area that went bald because of RU did not regrew.


I am trying everything (Cortisteroid, Diclophenac, Massage, Head stand....) Nothing as manage to re-awake the top right side...
I am waiting a scalp biopsies and will decide if maybe I will try PRP..

This COMPETELY sucs because 75% of my head is perfect. But 1/4 at the front right is fucked. Its almost as If RU triggered a BALD PATCH OF ALOPECIA AREATA...



GOOD LUCK EVERYONE.

 

[sonictemples]

has minoxidill EOD been effective for you in any sort of way? it didnt grow your hairline back but did it retain it?

I don't use minoxidil

 

[Bill Bones]

You don't want it to penetrate , that is the entire point. It should be degraded or prevented from reaching the hypodermis and vascularizing but reach the dermis.

I did a scalp biopsy and my DHT was almost non existent on my scalp while I had low-normal levels in my blood.

This is ideal.

Does this mean if I currently micro-needle once a week you would recommend I micro-needle the day after applying the topical dutasteride to reduce the chances of it going systemic? I swear I read in one of these forums you saying you also did micro needling but I couldn't find any comment where you specified when you mircorneedle in relation to when you apply the topical dutasteride.

Thank you so much for contributing to this community. I ordered a bottle of topical dutasteride last week and look forward to experimenting with it.

Also, anyone else besides Mustang with an opinion on the matter, please chime in.

 

[sonictemples]

You may want to consider joining the Discord chat as we have more info and anectodes there
discord.gg/43E6U6Zw8B

 

[losingbattle88]

Hello,

1)Yes full recovery. But the right side had slightly thinner hair. 50/50 terminal / velous hair. But il looked fixed. It was UNBELIEVABLE. Especially I am 36 years old. So It's like I was a hyper responder. By the way the first month I had 2 session of derma roller. 0.25mm

2)Not really. But I felt weird if I took too much. ball ache and anxiety disappeared and I felt stronger. Not back to 100% but back to 90%

3)0.25 mg morning , 0.25 mg night. Once every other day . ( At the time I did not know about half life ...)

4)Because I watch a video of MPMD. Big mistake this idiot has no clue what he is talking about. (The side are so dangerous.....)
Why: because I thought that additional protection from testosterone would help my top right side which was slightly thinner


Just to clarify. I bought in 2017 a 1 year supply of finasteride tablet and Dutasteride. I was thinning but regrew all with aggressive massage Argan oil/Castor Oil/Pumpkin seed oil/Blak seed oil + Peppermint/Rosemary/Thyme/lavender. The massage had a preventative effect from 2005-till 2019.

After reading label of side effects on 2017 I never tried any drugs.. ( I so regret because If I had the knowledge I have now. My hair would still look amazing)...
By the way my 5 years younger brother went bald at 20 years old.. I kept my hair till 35-36


I did nothing from 2017 till 2020 for my hair loss. I though It had stop so stop my nightly massage routine.

This was stupid because if I knew today I would still haver a full head of hair.
What happen is that from July 2019 my hair started thinning ON/OFF progressively (No bald patch) so I did not see it coming until September 2020 when I was laying on my Bed at 12 noon and the sun was beaming. That when I realized with horror that the shedding that happened (July-september 2020) made some serious damage.

1)I first tried topical Minoxidil (Lipogaine) and re-started my oil massage.
Thiss had the effect to not only break my now thin hair but to made me shed even more.

2) By October 2020. I had a U horse shoe, Camel toe on my forehead. This was extremely stressful because I went from full head of thin hair at the top front to this horrible U pattern in a WEEK. All the base of the weak hair broke...

3) I tried in the beginning of October 2020. finasteride and Dutasterider tablet. for 2/3 week . This immediately gave me side (Anxiety, Pannick, Low mood tiredness, low energy, low sex drive, feeling of being worried) No side effect. MY ***. THIS IS THE BIGGEST LIE. The initial oral dose was 1mg finasteride. 0.5 mg dutasteride. I tried 2 week finasteride eod then dutasteride 3/4 days. Side effect were s0 bad I stopped.

4) I had various quote from turquey for Hair transplant but they sounded dodgy. So I kept the minoxidil and tried Dr lampazula. But this MF would not send me some liposomal solution.. ( I had found out about potential systemic effect of PG/ethanol)

5)As i did not want to flu to brussel for the medication or a hair transplant. At this stage I did a DIY solution. I empty 30 capsules of Advodart into my lipogaine minoxidil 5%. So 30 * 0.5mg = 15mg in 60 ml. Thats a 0.025% concentration. So if you take 1ml you get 0.25mg. If you take 2ml that 0.5mg. The idea was to apply morning and Night and not going above 0.5mg

6) from October to November 2020. The side did not increase as much unless I use a large dosage. But the shedding increase. At this stage 1st of November I shaved because I was looking horrible

7) From mid November I started to feel baby hair and then It went exponential. My hair grew at an incredible rate. The top left side had twice more terminal hair. The top right side had 50/50 terminal/ vellous hair.

8) I had ordered Just to try Topical Min/finasteride from minoxidil max because I was seduced by their formula 15% minoxidil/ 0.1% finasteride/Aelai acid..]
9) As soon as I received the RU I added the 3G of RU to the Topical finasteride around mid-December I started to fell itchiness and my hair started to shed again.


BY 10Th of December. I had recovered most of the first shed. No scalp was visible on the top Left side. Hair line was fixed on left side and top right side was slightly thinner.

Literally few day after adding the RU. My hair started to degrade and went through a SECOND SHED. By mid January I had 2 large coin shape bald patch. The left side was smaller than the right side..


I stopped the combo with RU. And revert to the topical Min/finasteride at night with Topical minoxidil foam...

We are now in March. All the mid top plus crown is amazing. the top left is very good. The mid top right is fucked. After the second shed hair starting falling and grew miniaturised and brittle on half of the top right side.

It almost like the RU shocked my hair and force them into a cobo of accelerated thinning and telogen not followed by an Anagen phase. (Horrible)


So I suspect two things could have happened.
1) the move from my DIY lipogaine\Duta to Mimoxidil max. The move from 5% to 15% concentration of Minoxidil could have shocked my Hair
2) Maybe the RU that I added literally fucked my hair. I suspect its RU because when I continued the 15%minoxidil/0.1%finasteride I had no itchiness/Burninhg

Dutasteride is stronger than Finasteride. So I don't suspect switching from Topical Duta to Topical finasteride triggered the shed....


Bottom Line. I believe one the two variable above messed me up. I recommend to not do my mistake and to not change routine especially if everything is working...


My Ultimate recommendation to any newbie is to learn from my success and avoid my stupid mistake and to follow the protocol below :


Please take a hormonal blood test before first application . 2 week after, 3 month after.

1) Morning topical foam minoxil 5% (Monday to Sunday)
2) Morning and Night 1 ml Liposomnal Dutasteride 0.025% ( So 0.25mg morning/ 0.25 mg Night). Once a week ONLY
3)Sunday Night 1.5mm micro-needling. and leave 24H before re-apply any product.


When I had the most gain. I had plenty of water, sleep,Biotin Vitaminc C (Liposomal) , Zinc/Copper. Iron Protein , Magnesium...
I am not sure vitamine did anything


ps: I invested in a Dr Pen M8. I made the top left side grew even thicker. But the area that went bald because of RU did not regrew.


I am trying everything (Cortisteroid, Diclophenac, Massage, Head stand....) Nothing as manage to re-awake the top right side...
I am waiting a scalp biopsies and will decide if maybe I will try PRP..

This COMPETELY sucs because 75% of my head is perfect. But 1/4 at the front right is fucked. Its almost as If RU triggered a BALD PATCH OF ALOPECIA AREATA...



GOOD LUCK EVERYONE.

bro bro bro bro.... YES RU can be very risky. my friend used it on his hairline and said it killed his hairline and he got a hair transplant to fix it, also read other guys on reddit saying it thinned their hair.. and yes RU gave me 2 thin spots on my head after 2 months of daily application, just like alopecia areata no joke bro its crazy how you mention this and my hair did NOT thicken back up in those spots after quitting it. it became so thin I was shocked that I quit right away, didnt wanna mess around anymore with an experimental research chemical made in a chinese lab. PS: I wasnt even thinning in those 2 spots on my head before the RU.

btw dude PG in tiny amounts systemically isnt toxic to the body at all. and ethanol is simply grain alcohol.

 

[losingbattle88]

Does this mean if I currently micro-needle once a week you would recommend I micro-needle the day after applying the topical dutasteride to reduce the chances of it going systemic? I swear I read in one of these forums you saying you also did micro needling but I couldn't find any comment where you specified when you mircorneedle in relation to when you apply the topical dutasteride.

Thank you so much for contributing to this community. I ordered a bottle of topical dutasteride last week and look forward to experimenting with it.

Also, anyone else besides Mustang with an opinion on the matter, please chime in.

if you derma stamp at 1.5mm u WILL draw blood and the duta will 100% go systemic. I used 5mg with dermastamping 1.5mm and had nipple pain for a few hours. but never nippe pain on oral dutasteride at 0.5mg-1mg. besides needling every day isnt recommended anyway mostly just weekly. the study with mesotherapy used only 0.05% dutasteride I used 5mg.

 

[bucksins6x]

Does anyone know how long it take for dutasteride to reach homeostasis in the body. If the half life of dutasteride is 5 weeks, is it tye homeostasis will be reached in 4-5 times the half life so would max build up be reached by 20-25 weeks? Also, does taking a week off like every 4-5 weeks help?

 

[321nickname123]

Hello,

1)Yes full recovery. But the right side had slightly thinner hair. 50/50 terminal / velous hair. But il looked fixed. It was UNBELIEVABLE. Especially I am 36 years old. So It's like I was a hyper responder. By the way the first month I had 2 session of derma roller. 0.25mm

2)Not really. But I felt weird if I took too much. ball ache and anxiety disappeared and I felt stronger. Not back to 100% but back to 90%

3)0.25 mg morning , 0.25 mg night. Once every other day . ( At the time I did not know about half life ...)

4)Because I watch a video of MPMD. Big mistake this idiot has no clue what he is talking about. (The side are so dangerous.....)
Why: because I thought that additional protection from testosterone would help my top right side which was slightly thinner


Just to clarify. I bought in 2017 a 1 year supply of finasteride tablet and Dutasteride. I was thinning but regrew all with aggressive massage Argan oil/Castor Oil/Pumpkin seed oil/Blak seed oil + Peppermint/Rosemary/Thyme/lavender. The massage had a preventative effect from 2005-till 2019.

After reading label of side effects on 2017 I never tried any drugs.. ( I so regret because If I had the knowledge I have now. My hair would still look amazing)...
By the way my 5 years younger brother went bald at 20 years old.. I kept my hair till 35-36


I did nothing from 2017 till 2020 for my hair loss. I though It had stop so stop my nightly massage routine.

This was stupid because if I knew today I would still haver a full head of hair.
What happen is that from July 2019 my hair started thinning ON/OFF progressively (No bald patch) so I did not see it coming until September 2020 when I was laying on my Bed at 12 noon and the sun was beaming. That when I realized with horror that the shedding that happened (July-september 2020) made some serious damage.

1)I first tried topical Minoxidil (Lipogaine) and re-started my oil massage.
Thiss had the effect to not only break my now thin hair but to made me shed even more.

2) By October 2020. I had a U horse shoe, Camel toe on my forehead. This was extremely stressful because I went from full head of thin hair at the top front to this horrible U pattern in a WEEK. All the base of the weak hair broke...

3) I tried in the beginning of October 2020. finasteride and Dutasterider tablet. for 2/3 week . This immediately gave me side (Anxiety, Pannick, Low mood tiredness, low energy, low sex drive, feeling of being worried) No side effect. MY ***. THIS IS THE BIGGEST LIE. The initial oral dose was 1mg finasteride. 0.5 mg dutasteride. I tried 2 week finasteride eod then dutasteride 3/4 days. Side effect were s0 bad I stopped.

4) I had various quote from turquey for Hair transplant but they sounded dodgy. So I kept the minoxidil and tried Dr lampazula. But this MF would not send me some liposomal solution.. ( I had found out about potential systemic effect of PG/ethanol)

5)As i did not want to flu to brussel for the medication or a hair transplant. At this stage I did a DIY solution. I empty 30 capsules of Advodart into my lipogaine minoxidil 5%. So 30 * 0.5mg = 15mg in 60 ml. Thats a 0.025% concentration. So if you take 1ml you get 0.25mg. If you take 2ml that 0.5mg. The idea was to apply morning and Night and not going above 0.5mg

6) from October to November 2020. The side did not increase as much unless I use a large dosage. But the shedding increase. At this stage 1st of November I shaved because I was looking horrible

7) From mid November I started to feel baby hair and then It went exponential. My hair grew at an incredible rate. The top left side had twice more terminal hair. The top right side had 50/50 terminal/ vellous hair.

8) I had ordered Just to try Topical Min/finasteride from minoxidil max because I was seduced by their formula 15% minoxidil/ 0.1% finasteride/Aelai acid..]
9) As soon as I received the RU I added the 3G of RU to the Topical finasteride around mid-December I started to fell itchiness and my hair started to shed again.


BY 10Th of December. I had recovered most of the first shed. No scalp was visible on the top Left side. Hair line was fixed on left side and top right side was slightly thinner.

Literally few day after adding the RU. My hair started to degrade and went through a SECOND SHED. By mid January I had 2 large coin shape bald patch. The left side was smaller than the right side..


I stopped the combo with RU. And revert to the topical Min/finasteride at night with Topical minoxidil foam...

We are now in March. All the mid top plus crown is amazing. the top left is very good. The mid top right is fucked. After the second shed hair starting falling and grew miniaturised and brittle on half of the top right side.

It almost like the RU shocked my hair and force them into a cobo of accelerated thinning and telogen not followed by an Anagen phase. (Horrible)


So I suspect two things could have happened.
1) the move from my DIY lipogaine\Duta to Mimoxidil max. The move from 5% to 15% concentration of Minoxidil could have shocked my Hair
2) Maybe the RU that I added literally fucked my hair. I suspect its RU because when I continued the 15%minoxidil/0.1%finasteride I had no itchiness/Burninhg

Dutasteride is stronger than Finasteride. So I don't suspect switching from Topical Duta to Topical finasteride triggered the shed....


Bottom Line. I believe one the two variable above messed me up. I recommend to not do my mistake and to not change routine especially if everything is working...


My Ultimate recommendation to any newbie is to learn from my success and avoid my stupid mistake and to follow the protocol below :


Please take a hormonal blood test before first application . 2 week after, 3 month after.

1) Morning topical foam minoxil 5% (Monday to Sunday)
2) Morning and Night 1 ml Liposomnal Dutasteride 0.025% ( So 0.25mg morning/ 0.25 mg Night). Once a week ONLY
3)Sunday Night 1.5mm micro-needling. and leave 24H before re-apply any product.


When I had the most gain. I had plenty of water, sleep,Biotin Vitaminc C (Liposomal) , Zinc/Copper. Iron Protein , Magnesium...
I am not sure vitamine did anything


ps: I invested in a Dr Pen M8. I made the top left side grew even thicker. But the area that went bald because of RU did not regrew.


I am trying everything (Cortisteroid, Diclophenac, Massage, Head stand....) Nothing as manage to re-awake the top right side...
I am waiting a scalp biopsies and will decide if maybe I will try PRP..

This COMPETELY sucs because 75% of my head is perfect. But 1/4 at the front right is fucked. Its almost as If RU triggered a BALD PATCH OF ALOPECIA AREATA...



GOOD LUCK EVERYONE.

Thanks for the detailed write up.

I'm currently also thinking of adding topical dutasteride (to use it once or twice a week, like you mentioned, given its long half-life).
What do you think of this topical dutasteride solution from Minoxidilmax? It has a 0.1% dosage, is that fine? Seems like a high dosage to me. https://www.minoxidilmax.com/topical-dutasteride-Duderma

Also saw Minoxidil Express 0.5% topical dutasteride but that's 5mg per ml? Seems crazy high as well or am I wrong?

I'd rather not make my own but order a pre-made solution.

And to everyone else, are there any other good topical dutasteride solutions out there?

 

[Mister Licorne]

I have tried stem cells injections, minoxidil, PRP, mesotherapy, oral minoxidil (loniten), RU, finasteride, dutasteride, topical finasteride and topical dutasteride, dermarolling, saw palmetto, topical saw palmetto, laser cap, dutasteride mesotherapy and probably many other things the past 15 years.

The 4 things that made the greatest difference on my male pattern baldness were:

1) Oral Minoxidil. You grow hair like a Lion. Side effects are bad, it's a powerful med for high blood pressure. I naturally have very low blood pressure, not for me.
2) Dutasteride Mesotherapy. Once every 15 days. 2mm deep. 2ML of Dutasteride. Using a dermapen.
3) Topical Dutasteride. Stopped my hair loss cold. No sides.
4) Dermarolling. It really works.

What did not work or had too many side effects

1) Oral finasteride and dutasteride, side effects were bad
2) Topical finasteride, same sides as oral
3) PRP, did nothing
4) Stem cells did nothing
5) Saw Palmetto, nada
6) Biotin, vitamins, scalp massages

What worked moderately

1) Laser Cap. It did thicken my hair, still use it 3 times a week.
2) RU, hard to tell as I have no hair loss on topical dutasteride and have none since stopping RU.

Thank you for sharing this. I'd like to know what % of dutasteride you used in the dutasteride mesotherapy. I'm doing the same but my solution is just 0,025% and I don't know if that is a good concentration (it has more things, such as latanoprost, alfatradiol, and Minoxidil)

 

[Mustang]

I stopped using it since topical dutasteride is enough but I used 0.05%, you can also try 0.01%

Latanoprost watch out.