Topical spironolactone Users

iamnaked

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mvpsoft said:
Emu oil is likely to help "carry" actives of any kind into the skin. Applying emu oil after applying any topical wil likely increase that topical's effectiveness. You should probably wait a few minutes for the topical to dry just a bit, however.

My Cremona to a Jew's Trump glycerol is a better solvent than emu oil.
 

mvpsoft

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iamnaked said:
mvpsoft said:
Emu oil is likely to help "carry" actives of any kind into the skin. Applying emu oil after applying any topical wil likely increase that topical's effectiveness. You should probably wait a few minutes for the topical to dry just a bit, however.

My Cremona to a Jew's Trump glycerol is a better solvent than emu oil.

Emu oil is not a solvent. You put it on after an active has been applied to the skin or scalp, allowing 10 minutes or so for the active to dry partially. Emu oil is composed of very small molecules and easily penetrates the skin. It is this penetration action that apparently leads to the increased skin penetration of the actives themselves. Now, if you put on emu oil prior to applying an active or too soon after it, the emu oil will act as a barrier and lessen skin penetration of the actives.

Squalane has a similar function.

That is the theory, anyway. I do not know of any proof that the theory is accurate.
 

momo

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Even on this thread I could not find one concise response of success.
Anyhow, I'm into purchasing spironolactone of Dr. Lee. I'm thinnng (not receiding) and I wonder if one could apply spironolactone 5% cream on place with hair on, or should I better get the 2% solution.
 

-cj-

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momo said:
Even on this thread I could not find one concise response of success.
Anyhow, I'm into purchasing spironolactone of Dr. Lee. I'm thinnng (not receiding) and I wonder if one could apply spironolactone 5% cream on place with hair on, or should I better get the 2% solution.

That is because no one has used spironolactone on it's own that I know of. I use the 2% all over my male pattern baldness areas. I just bought the 5% for the temples.
 

momo

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spironolactone exists for about 20 years. No one has EVER used it alone? I don't buy that.

Besides, you don't need to use it alone in order to test it. You just need someone who doesn't use finasteride or dutasteride on their regimen, and there are many of them (simply since tons had side effects).

I'm using xandrox alone for quite some time, maintaining (with a slight deterioration I believe), and when I add spironolactone, i will most definitely be able to identify any change, and then attribute any new regrowth to it.

(thanks for your response ;)
 

-cj-

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momo said:
spironolactone exists for about 20 years. No one has EVER used it alone? I don't buy that.

Besides, you don't need to use it alone in order to test it. You just need someone who doesn't use finasteride or dutasteride on their regimen, and there are many of them (simply since tons had side effects).

I'm using xandrox alone for quite some time, maintaining (with a slight deterioration I believe), and when I add spironolactone, i will most definitely be able to identify any change, and then attribute any new regrowth to it.

(thanks for your response ;)

I was refering to this board sorry :p.

I use Sprio & minoxidil, after 1 month I have noticeable new dark hair coming up in my temples. I can't say what did this, but I just know I'm not going to stop :p.
 

lordhair

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Well I have been back on spironolactone for just over a week (a homemade 3% version) and I have had the return of the nasty headaches I got last time I used it

So It's back to looking around for something else
 

hairhaircomeagain

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cj --> Any sides using spironolactone ? I heard it can be dangerous even topically
 

Lessofarockstar

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hairhaircomeagain said:
cj --> Any sides using spironolactone ? I heard it can be dangerous even topically

Dangerous? How so?
I got some gyno from finasteride, and I am kinda worried that topical spironolactone is making it dificult for me to recover from that sh*t.
Have you got any studies or anything?
 

iamnaked

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hairhaircomeagain said:
cj --> Any sides using spironolactone ? I heard it can be dangerous even topically

It's not absorbed systemically in levels anywhere near high enough to be dangerous.

Even orally, you have to be on pretty high doses before you may see some demasculinising traits. Even so, these are not 'dangerous' per se. It's just that most men don't like the aesthetic of having tits.
 

Lessofarockstar

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iamnaked said:
hairhaircomeagain said:
cj --> Any sides using spironolactone ? I heard it can be dangerous even topically

It's not absorbed systemically in levels anywhere near high enough to be dangerous.

Even orally, you have to be on pretty high doses before you may see some demasculinising traits. Even so, these are not 'dangerous' per se. It's just that most men don't like the aesthetic of having tits.

Iamnaked, I think you're right.
Most likely my hormones are just still screwed up from finasteride, and just the slightest bit of spironolactone in my system seems to make things worse. So I think I will stop spironolactone completely and see if it gets better. When I have absolutely no gyno signs, I will try starting spironolactone again to see if it makes a difference.
 

Felk

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Lessofarockstar said:
Iamnaked, I think you're right.
Most likely my hormones are just still screwed up from finasteride, and just the slightest bit of spironolactone in my system seems to make things worse. So I think I will stop spironolactone completely and see if it gets better. When I have absolutely no gyno signs, I will try starting spironolactone again to see if it makes a difference.

I think you're being overly cautious. "There is no evidence that topical spironolactone is systematically absorbed to a level of any significance" says Doctor Proctor, and Dr Lee says it's not absorbed systematically at all, which could be what Proctor means.

Hell, people winge about topcial spironolactone not being effective enough on the hair follicles, let alone any effects on the rest of your body.

And it's not just Socks who takes it orally - it's a strong prescription drug for blood pressure or something, and is used in men for this purpose. The fact that it has strong antiandrogen properties is a side effect.
 

Lessofarockstar

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Felk I tend to agree. But i just dont want to take the chance. I'm very in to my bodybuilding, and I dont want to screw up all my hard work. I'd rather wait a few more weeks and be on the safe side.
Anyway, I emailed minoxidil.com about it. Hopefully they'll get back to me soon.

And I know it came off overly cautious, but trust me if you had a gyno scare you'd be cautious too.
 

-cj-

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Lessofarockstar said:
Felk I tend to agree. But i just dont want to take the chance. I'm very in to my bodybuilding, and I dont want to screw up all my hard work. I'd rather wait a few more weeks and be on the safe side.
Anyway, I emailed minoxidil.com about it. Hopefully they'll get back to me soon.

And I know it came off overly cautious, but trust me if you had a gyno scare you'd be cautious too.

I have no noticable sides from spironolactone after 1 month of use. I am into bodybuilding as well so I pay attention to these things. I'm not really concerned about spironolactone giving me side effects, but if it does then I'll definitely notice :p.
 

Felk

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Lessofarockstar said:
And I know it came off overly cautious, but trust me if you had a gyno scare you'd be cautious too.

Yeah im sure i would be! I didnt mean to make out that you shouldnt worry about it or anything, i was more concerned about you undoing the possible good work of your spironolactone treatment.

But if you havent been on long, it probably wont matter anyway
 

joeylloyd

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I was on Dr Lee's 5% spironolactone for about 18 months. It seemed to work okay but when I heard about its potential systemic effects I had to stop. YMMV.
 

Felk

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iamnaked said:
I've been on it for more than a year now. I definitely feel it's helping, although that's not a scientific endorsement, since I've been using other stuff. I don't think you have too much to lose from trying it though. I make my own topical, and it's ve-ery cheap.

Hey iamnaked, whats in your mix?

What do you use as a base to dissolve the spironolactone into?
 

iamnaked

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Felk said:
iamnaked said:
I've been on it for more than a year now. I definitely feel it's helping, although that's not a scientific endorsement, since I've been using other stuff. I don't think you have too much to lose from trying it though. I make my own topical, and it's ve-ery cheap.

Hey iamnaked, whats in your mix?

What do you use as a base to dissolve the spironolactone into?

Boots rosewater glycerin. V. good solvent, and a skin moisturiser to boot. Each time I apply I put a single 0.25 miligram spirotone pill in with about a mil of glycerin, wait for about 1/2 an hour for it to dissolve, then whack it on my affected areas.
 
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