Topical spironolactone Users
- Thread starter ManUFan
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G
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Guest
Everyone,
If i want to use spironolactone down the road, should I be using the 5% cream or 2% liquid? I would be using it to maintain. And do I need to use anything with it? Or will dutasteride+spironolactone be all the dht blocking that I need?
thanks
If i want to use spironolactone down the road, should I be using the 5% cream or 2% liquid? I would be using it to maintain. And do I need to use anything with it? Or will dutasteride+spironolactone be all the dht blocking that I need?
thanks
G
Guest
Guest
thanks college.
college,
is there anything else someone could use to block DHT besides an oral 5ar inhibitor and spironolactone?
college,
is there anything else someone could use to block DHT besides an oral 5ar inhibitor and spironolactone?
eucapil, spironolactone, and RU block androgen receptors topically.
4 fatty acids block 5ar topically
dutasteride and finasteride block 5ar intermally, though some people try it topically.
most topicals have to be applied in a medium that does not evaporate fast. I don't know how eucapil gets around that.
i really think my hair is getting thicker and I don't know what part of my regimen is doing it. The tiny fuzz in the hair line when from 1/16 inch to 1/8 inch in the center, matching my left side.
flutamide only works systemically but can still regrow hair. Appearantly your body can handle having androgens blocked everywhere like it can handle DHT inhibited everywhere. But i suspect flutamide orally might mess some stuff up eventually.
4 fatty acids block 5ar topically
dutasteride and finasteride block 5ar intermally, though some people try it topically.
most topicals have to be applied in a medium that does not evaporate fast. I don't know how eucapil gets around that.
i really think my hair is getting thicker and I don't know what part of my regimen is doing it. The tiny fuzz in the hair line when from 1/16 inch to 1/8 inch in the center, matching my left side.
flutamide only works systemically but can still regrow hair. Appearantly your body can handle having androgens blocked everywhere like it can handle DHT inhibited everywhere. But i suspect flutamide orally might mess some stuff up eventually.
jimmyjames
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so nine pages later and it seems like the jury's still out when it comes to spironolactone? basically my question is: if you're not using Propecia, is spironolactone the only other REAL option to block DHT? and is this stuff greasy/smelly?
flutamide only works systemically but can still regrow hair. Appearantly your body can handle having androgens blocked everywhere like it can handle DHT inhibited everywhere. But i suspect flutamide orally might mess some stuff up eventually.
Keep in mind though that If using a 2% alcohol formula you would be systemically absorbing about 16% of the drug which comes to a very minimal and likely harmless amount.
Keep in mind though that If using a 2% alcohol formula you would be systemically absorbing about 16% of the drug which comes to a very minimal and likely harmless amount.
JWM,
50% was absorbed in the study you are refering to. They wiped the skin with cotton swabs after 6 hours and got 50% off the scalp. Yes, metabolites of 16% was found in urine. The rest was unaccounted for, probably bonded to androgen receptors all over the body, or maybe stuck in some fat.
Every study on flutamide that measured its affects in more than one area has found it has an equal effect at the point of application as it does at the far away other point they measured where it was not applied. What does that say about its effects on the rest of the body? If you want to take 2.5mg of Avodart a day, but don't have the money and don't want the extra DHT, then cut up a flutamide pill and gradually take higher oral doses to see what you can handle. It is the poor man's dutasteride. But beware of possible side effects. I would NOT do that myself.
50% was absorbed in the study you are refering to. They wiped the skin with cotton swabs after 6 hours and got 50% off the scalp. Yes, metabolites of 16% was found in urine. The rest was unaccounted for, probably bonded to androgen receptors all over the body, or maybe stuck in some fat.
Every study on flutamide that measured its affects in more than one area has found it has an equal effect at the point of application as it does at the far away other point they measured where it was not applied. What does that say about its effects on the rest of the body? If you want to take 2.5mg of Avodart a day, but don't have the money and don't want the extra DHT, then cut up a flutamide pill and gradually take higher oral doses to see what you can handle. It is the poor man's dutasteride. But beware of possible side effects. I would NOT do that myself.