Treatment of male pattern baldness.... results from 1988!

The Natural

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Primrose oil is recommended by Dr. Udo Eramus. I have used borage oil in the past, and would advise against it for a number of reasons (see www. udoerasmus.com), the most important of which is that it doesn't work/help.
 

elvis123

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2020 said:
I think we all already decided on these supplements:


Life Extension Super Omega-3 EPA/DHA with Sesame Lignans & Olive Fruit Extract
http://www.amazon.com/gp/product/B002HI ... PDKIKX0DER


Now Foods, Super Primrose 1300 mg
http://www.amazon.com/gp/product/B0018O ... ct_title_1


I'll start taking these next month... :punk:


That looks good. Wiki says GLA can be made from LA but as you age that process is weakened so you can get GLA directly from EPO. But Wiki also says that the benefits of GLA are still unproven and widely disputed...Would it be better just to stick with fish oil???
 

Jacob

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I think the Swanson one is a much better deal..especially with their 10% off or other coupon codes available out there.

But the echium oil seems to be higher in GLA...plus it contains something extra- SDA-Stearidonic Acid(black currant also contains it). I think the ETA-Eicosatetraenoic Acid is also another the others don't have...although I don't see it listed in all echium products, for whatever reason.
 

Jacob

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SDA readily converted to EPA
With EPA being a major precursor of anti-inflammatory eicosanoids, any molecule that leads to higher EPA status in the body is likely to contribute to these health benefits. ALA is at the top of n-3 pathway and is considered truly essential (see pathway).The body can convert this molecule to EPA, however, only 2-5% of ALA molecules are turned into EPA. This is caused by Delta-6-desaturase (D6D), which is rate limiting in humans. SDA, therefore, overcomes this problem, as D6D in vivo is not needed to synthesize EPA. Conversion rates of SDA to EPA lie around 20-30 %, thus substantially higher than ALA. This is also confirmed by studies that show 3 x SDA provides the same physiological effects as 1 x EPA, as measured by the CVD risk factors omega-3 index and serum triglycerides.


Synergy between SDA and GLA
As indicated above, both SDA (through EPA) and GLA (through dihomo-GLA) produce anti-inflammatory eicosanoids. Question is, do these components show synergistic effects in the body? Considering the n-6 pathway, dihomo-GLA can potentially be converted to Arachidonic acid (AA). AA, in turn, can deliver inflammatory eicosanoids. Though it is clear from many studies that GLA is safe to consume and shows many benefits, some ARA will be formed and thus be incorporated in cell membranes.
Surprisingly, EPA prevents the formation of AA from dihomo-GLA in humans, creating a full anti-inflammatory set of pre-cursors when consuming Echium oil. Though this theoretically already makes sense, it has also been shown in research done under (physiological) stress and injury. Combinations of GLA and EPA outperformed the individual fatty acids looking at different study outcomes. The combination of GLA and EPA is already used in clinical food when treating lung diseases with inflammatory backgrounds.

http://www.echiumoil.eu/health-benefits.php

SDA is the precursor to EPA (eicosapentaenoic acid), with SDA producing up to 5 times more EPA than other vegetarian omega-3 oils. EPA plays an integral role in the proper functioning and structure of the brain. EPA may improve the cardiovascular system by reducing the stickiness of platelets in the blood and by lowering blood pressure. It is also converted into prostaglandins (hormone-like substances which control many bodily functions) and leukotrienes (important for the correct functioning of the immune system) which regulate inflammation and pain, and also help to maintain healthy joints. The omega-6 fatty acid gamma linolenic acid (GLA) is vital for the structure of the brain –it ensures that cell membranes are permeable, thus contributing to efficient brain function. GLA is the precursor to dihomo gamma-linolenic acid (DGLA) which is converted into prostaglandins which regulate inflammation, pain, blood clotting and fluid balance. Oleic acid, usually associated with the ‘Mediterranean diet’ has been shown to slow the development of heart disease by lowering total cholesterol level and raising levels of high-density lipoproteins (HDL or ‘good’ cholesterol), whilst lowering low-density lipoproteins (LDL or ‘bad’ cholesterol).

http://www.pharmepa.com/index.php?p...ategory_id=7&option=com_virtuemart&Itemid=360
 

Jacob

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Well..since it seems anti-inflammatory is one of the things you're going for..it would be a bonus. Seems like there's other health benefits as well.

But if going for purely hair benefits..millet seed oil/extract may make the most sense.
The supercritical
(CO2) millet seed (Panicum miliaceum)
oil extract contains valuable linoleic acid, the
triterpenoid miliacin as well as other phytosterols
and squalene are important for sustaining
hair growth. Miliacin increases cell metabolism,
stimulates cell proliferation and tissue
regeneration. Clinical studies have proven it
supports hair growth, has anabolic activity
and supports the formation of lustrous and
healthy hair. Miliacin activates skin repair
mechanisms and has anti-inflammatory properties.
It is wound healing and has positive
effects in the case of skin ulcers and purulent
skin conditions.
 

squeegee

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The Natural said:
How does it affect your hair is what I would like to know.

Get back to page 1 and start to read. :woot:
 

The Natural

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In other words, have you or anyone you know tried this particular supplement, which on its face, seems to be one in a long list of products that "make the hair grow faster."

If not, then perhaps, squeegee can be our guinea pig this time.
 

LawOfThelema

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Now Foods, Super Primrose 1300 mg
http://www.amazon.com/gp/product/B0018O ... ct_title_1

So to get the 6g daily used in the study you would need 5 doses.

How many capsules do you need to get 1 dose? (edit: it's one cap to get 1300 mg, and its 120 per bottle, so thats not even a months worth per bottle... still not bad price)

At this point it probably just becomes cheaper to buy evening primrose oil itself and take it by the spoonful.

Or better, to just apply it to your scalp.

Does anyone know the density in g/mL or g/ fluid ounce so we can find out how many doses come in the bottles of pure evening primrose oil lol

Life Extension Super Omega-3 EPA/DHA with Sesame Lignans & Olive Fruit Extract
http://www.amazon.com/gp/product/B002HI ... PDKIKX0DER

This one is just great. That is more EPA and DHA that I have seen in any prior supplement.
 

The Natural

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Jacob said:
Well..since it seems anti-inflammatory is one of the things you're going for..it would be a bonus. Seems like there's other health benefits as well.

But if going for purely hair benefits..millet seed oil/extract may make the most sense.

Why are you not recommending Krill oil anymore?
 

Jacob

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The Natural said:
Jacob said:
Well..since it seems anti-inflammatory is one of the things you're going for..it would be a bonus. Seems like there's other health benefits as well.

But if going for purely hair benefits..millet seed oil/extract may make the most sense.

Why are you not recommending Krill oil anymore?

While I don't really recommend things :woot: ....I personally do better(feel better...digestion related..etc) with plant-based oils. That's not to say I wouldn't take krill or even fish oil again, if it's the right product and on sale- which is pretty much what I've been doing for the longest time- just grabbing decent products that are on sale. Swanson's krill was the last krill I took..not too long ago..due to a nice sale on it. The only exception to that is the kinda pricey Immuno Viva Core I've been taking again. I'm taking these oils for other health benefits..if they help with hair..I won't complain(nor would I know..probably).

The echium oil liquid I posted earlier may be my next one to use for awhile though..sale or no sale. That and the millet seed oil combo.

LawOfThelema...I'm pretty sure there are others with more EPA & DHA...
 

squeegee

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The Natural said:
In other words, have you or anyone you know tried this particular supplement, which on its face, seems to be one in a long list of products that "make the hair grow faster."

If not, then perhaps, squeegee can be our guinea pig this time.


Taking a shitload of omega 3 right now along with Sesamin from Scivation and Borage oil. Topically still on Miconazole Nitrate and minoxidil. I added arnica gel at night... Inhibit platelet aggregation with Diclofenac sodium.. inhibit Cox-2. Both OTC sh*t easily available at our nearest drugstore.Probably going to add EPR soon..
 

squeegee

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The Natural said:
Jacob said:
Well..since it seems anti-inflammatory is one of the things you're going for..it would be a bonus. Seems like there's other health benefits as well.

But if going for purely hair benefits..millet seed oil/extract may make the most sense.

Why are you not recommending Krill oil anymore?

Krill oil is poor in EPA/DHA normally and over expensive.
 

The Natural

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Well, as has been stated before, it is not just a matter of numbers. Borage oil contains, purportedly, the highest amount of GLA per, but this oil is not going to help, at least not for any significant period of time. In fact, the exact opposite may occur, if you take too much of it.
 

squeegee

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The Natural said:
Well, as has been stated before, it is not just a matter of numbers. Borage oil contains, purportedly, the highest amount of GLA per, but this oil is not going to help, at least not for any significant period of time. In fact, the exact opposite may occur, if you take too much of it.


This is why you take Sesamin and Omega 3 with it. viewtopic.php?f=23&t=74913&st=0&sk=t&sd=a&start=60

Raise DGLA levels and keep the D5D in check. :woot: The Natural.. you have to read more..we are not on the IH forum here BTW LOL where CausticSymmetry gives all the answers.
 

The Natural

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LOL! Dude, I know exactly where I am :) .

Know where you are too: about 5-6 years behind me, if you think that anything other than this Primrose oil variable will result in sustained hair regrowth. The other oils have been tried (including the sesamin) unsuccessfully, unfortunately.
 
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