UK male pattern baldness is rampant

[Ventures]

uff yea, he has some frontal recession and hair loss, he is probably using concealers, cause his hair looks good at other photos like this one http://cdn01.cdn.justjared.com/wp-c...justin-mitika-elle-women-in-television-15.jpg


but thanks on this photo, Fred, it is clearly he hasn't got masculine body and zero body hair.


this ginger guys are so unlucky, the have very unmusculine skin and body, but they do have hair loss issues which means only one thing, high AR affinity but on wrong place, top of the head, instead abdomen, legs, penis(sorry )

Fred, you also dont have body hair, did you test your DHT levels in blood serum ?

 

[hair_nag]

The way I see it its pretty much all about genetics and androgen sensitivity, you can have any combination of hairy body and hairloss or lack there of. BUT if you take any individual man and inject him with lots of DHT it would cause increased body hair and likelihood of hairloss, but in real life men aren't being injected with DHT, so their genes determine their hair (body and scalp).

 

[Wolf Pack]

^ Plenty of body builders are on steroids at 3 times above the normal range. That T will convert to DHT, yet they lose no hair. As it's not sensitive to it and they don't have male pattern baldness.

 

[SayifDoit]

Some men just don't have sensitive androgen receptors in their scalp. Just because they pump themselves full of hormones means nothing. It is true though men while aging their androgen receptors become more sensitive, that is why its rare you see a really old man without some minor hair loss.

 

[resu]

It seems that the older we get the more body hair we get, like when you're old your ears get hairy, so more DHT means less scalp hair if you're male pattern baldness prone.

 

[Ventures]

It seems that the older we get the more body hair we get, like when you're old your ears get hairy, so more DHT means less scalp hair if you're male pattern baldness prone.

it's because body hair doesn't suddenly develop when you get old, but it is a continuos process which is happening oall the time since the age you've turned in puberty and your body's started producing DHT. Even low DHT levels, if exposed long period of time to DP can turn velus body hair into terminal stage which is then recognised as body hair.

And remember as you said, that old people have more DHT generated inside their body and scalp hair follicles + apparently upregulation of ARs.

 

[hair_nag]

it's because body hair doesn't suddenly develop when you get old, but it is a continuos process which is happening oall the time since the age you've turned in puberty and your body's started producing DHT. Even low DHT levels, if exposed long period of time to DP can turn velus body hair into terminal stage which is then recognised as body hair.

And remember as you said, that old people have more DHT generated inside their body and scalp hair follicles + apparently upregulation of ARs.

Old men have less DHT production than young men, they have just been exposed to DHT for a lot longer.

 

[resu]

I thought old men have less Testosterone and more DHT.

 

[sjbuk]

I agree there is a lot of hair loss in the UK . But as for fitting in, every time I see a young bald guy here, he is usually walking the streets alone with no companions. The nw1's usually have a girl on their arm or people around them. I don't think they fit in at all, baldness is still considered a defect by society.

True that baldness is often seen as fair game to mock, in UK anyway, but its often in the mind to some extent I would say if its a 'defect'

 

[abcdefg]

Someone really just needs to figure out the whole androgen receptor thing and why head hair reacts negatively to androgens but body hair grows in response to androgens. What are the patterns of receptors in different men and how strongly does it correlate to rate/pattern of loss. Those are much more important than raising/lowering absolute androgen levels.

 

[Ventures]

Someone really just needs to figure out the whole androgen receptor thing and why head hair reacts negatively to androgens but body hair grows in response to androgens. What are the patterns of receptors in different men and how strongly does it correlate to rate/pattern of loss. Those are much more important than raising/lowering absolute androgen levels.

Absolutely. But it isn't simple as that. The first clue would be to find some kind of selective androgen receptor modulator for hair follicles, we already have selective estrogen receptor modulator meds for women breast cancer treatment.

and another step would be to block/inhibit enzyme which is responsible for change in hair cycles and growth of hair follicles. Is it PGD2, PGE2 or something else, science hasn't found yet. But we know there must be some kind of enzyme which in downstream effect and "tells" follicles to stop produce new hair.

Imagine we have this two meds for treating AR modulation of hair follicles and enzyme production. It doesn't necessary mean this two meds must be 100% effective but we would have much more advantage then using old fashion finasteride and minoxidil.