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Epigenetic changes could possibly impact and either improve or worsen baldness. As a practical matter, it is all but entirely based upon genetics. I have seen identical twin pics who differ somewhat in the stage of baldness but that's not that common. If one identical twin goes skin bald then the other one has a phenomenally high probability of also being completely bald. Penis size might be similar in this aspect.
Under this reasoning, however, estradiol appears to be able to invoke enormous change in things previously dominated by male receptors. Thus, estradiol epigenetically turns off the male baldness gene, but this occurs along with every single indicia of masculinity from head to toe, especially the breasts and genitalia immediately changing tissue composition. Men and women's skin per se differs enormously and the skin changes come all but immediately. The hair is the least responsive thing to HRT for many people which might mean that balding areas have enormous numbers of hair receptors to which androgens tightly cling. It could take a decade or longer for long-term estradiol use to reverse baldness, the most prominent form of sexual dimorphism among humans I expect.
Under this reasoning, however, estradiol appears to be able to invoke enormous change in things previously dominated by male receptors. Thus, estradiol epigenetically turns off the male baldness gene, but this occurs along with every single indicia of masculinity from head to toe, especially the breasts and genitalia immediately changing tissue composition. Men and women's skin per se differs enormously and the skin changes come all but immediately. The hair is the least responsive thing to HRT for many people which might mean that balding areas have enormous numbers of hair receptors to which androgens tightly cling. It could take a decade or longer for long-term estradiol use to reverse baldness, the most prominent form of sexual dimorphism among humans I expect.
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