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Why Do Older Guys Lose Hair If Testosterone/dht Decreases With Age?

Swoop

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https://www.ncbi.nlm.nih.gov/pubmed/28593683

Aging in hair follicle stem cells and niche microenvironment.


Hair graying and hair loss are prominent and common characteristics of the elderly population. In some individuals these processes can significantly impact their quality of life, leading to depression, anxiety and other serious mental health problems. Accordingly, there has been much interest in understanding the complex physiological changes within the hair follicle in the aging individual. It is now known that hair follicles represent a prototypical stem cell niche, where both micro- and macroenvironmental influences are integrated alongside stem cell-stem cell and stem cell-stem niche interactions to determine hair growth or hair follicle senescence. Recent studies have identified imbalanced stem cell differentiation and altered stem cell activity as important factors during hair loss, indicating new avenues for the development of therapeutic agents to stimulate hair growth. Here, we pull together the latest findings on the hair follicle stem cell niche and the multifactorial interactions underlying the various forms of hair loss.
 

Bigbone

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Where does it say that DHT increases with age? I've read that DHT/T decreases with age while estrogen goes up slightly. I imagine that body hair works the same way as the head on our heads when it comes to sensitivity. I mean, there are still a lot of men with low DHT and T-levels and still developing a lot of body hair over time, while losing it on top of the head.
 

kiwipilu

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that schwarzy gif is gold. that's the face we have when ppl tell us bald joke
 

Trichosan

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Where does it say that DHT increases with age? I've read that DHT/T decreases with age while estrogen goes up slightly. I imagine that body hair works the same way as the head on our heads when it comes to sensitivity. I mean, there are still a lot of men with low DHT and T-levels and still developing a lot of body hair over time, while losing it on top of the head.

Estrogen levels can decrease with age also, but there is such a complex harmony between these things the effects vary with the individual. Even at my age, I have more T (750) than some in their 20s but not the strength or libido I had even 5 years ago. Meanwhile, hairloss on top of my head seems to have stabilized for many years, body hair and color the same, but almost all the hair on my legs has disappeared. I think hair follicles collectively have a separate intelligence and they know how to f*** with us. Devious.
 
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