Gadgetine

Exploring The Hormonal Route. Hair=life.

sg2000

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View attachment 190424

Ok, so my DHT is crazy, but I decided just to live with it atp.
Hard to tell why it is like that, because my ACTH, 17-OHP, Cortisol, Aldosterone, Androstenedione, 3a-diol are all near low reference and DHEA-S is somehow even lower than month ago. Also, I've no clue why prolactin didn't affect anything, as well as where it came from.
Overall, I feel good, my hair doesn't fall out, skin is good, bobs are sensitive, fat is redistributed well, all even considering very high SHBG. The only downsides are more sebum on scalp (especially on forehead) and hair is kinda coarse and less soft, which makes the texture a bit weird.
DHT, tho, is definitely there, but finding out what causes it is (IMO) not worth it for me atp. I guess it's either one of CAH variations, or sort of DHT inactivation issue like 3a-HSD deficiency, or its inhibition by bile acids. I honesly blame the bile acids, because noticing some short-lived scalp inflammation from time to time when my diet is too high on fats and hair getting worse too. Regardless, even if its CAH, I have no way of treating it, because my tolerance to corticosteroids is just no bueno. Gonna just reduce my E dose a lil bit and... well, just move on with my worthless DHT mutant life.
is that dht mutant scenario common or happens for a slight portion of people?Have you ever used or you use bicalutamide?
Today my blood test will be out after like 2 weeks of completly dropping cpa but i didnt measured shbg...
 
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sg2000

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also did you have aggressive Androgenetic Alopecia before hrt??if yes how much aggressive?
 

sg2000

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you have high shbg despite injecting 5 mg weekly een injections...
i wonder how high is mine since im injecting 8 mg a week.. next time ill test it
 

sg2000

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yea
Your job now is to start decreasing that huge estradiol result. It will give issues long term
but wtf im a bit mad to the lab cause last time used different values.I converted dht value and it is 4 ng dl so its ok.
but prolactin is still high no wonder since e2 turned out to be so high
 

Adri23

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No you are not gonna die but you have chances of getting upregulation the longer you keep those levels. It took me one year of high e2(not even that high tho) to my body to spike SHBG and increase DHT, so if I were you I would stay safe and lower estradiol to 300 pg/ml at trough, it will be better for the long term.
 

Adri23

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yea

but wtf im a bit mad to the lab cause last time used different values.I converted dht value and it is 4 ng dl so its ok.
but prolactin is still high no wonder since e2 turned out to be so high
Yes prolactin is still high, but that's normal with that high e2 and you also stopped CPA not too long ago. After 3 months of stopping CPA I still had high prolactin. Took 5-6 months to my prolactin to get low.
 

sg2000

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wh
No you are not gonna die but you have chances of getting upregulation the longer you keep those levels. It took me one year of high e2(not even that high tho) to my body to spike SHBG and increase DHT, so if I were you I would stay safe and lower estradiol to 300 pg/ml at trough, it will be better for the long term.
what should i do next i want to inject weekly but dunno my exact dosage to not spike those levels so high
 

sg2000

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tomorrow
What is your current dosage?

300 pg/ml at trough is a good balance
is my injection day and im thinking about doing 0.15 ml (6 mg?).
Im dosing 0.2 ml 8 mg a week!!
however take note that i did the test the day after my next injection… but theyre high anyway
 

Adri23

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Tomorrow is my injection day and im thinking about doing 0.15 ml (6 mg?).
Im dosing 0.2 ml 8 mg a week!!
however take note that i did the test the day after my next injection… but theyre high anyway
Try 6 mg and see. It gives me 378-385 pg/ml. I want estradiol at 300 pg/ml at trough, prob even less after I get the orchi.
 

Adri23

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this but when they are sore, my scalp feels the best
Mine feel exactly the same(sh*t as always ofc). It's so fucked up to get so much nipple pain after 3 years tho.
 

Ryuzaki hedeki

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Mine feel exactly the same(sh*t as always ofc). It's so fucked up to get so much nipple pain after 3 years tho.
Are you considering raloxifene or any other serm for this issue? Because I'm going through the same thing even after quitting e2 slowly!!
 
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