0.03/0.04mg Of Finasteride. Please Help Me With This Research Project.

[NormanNorwood]

Obligatory Micro-dosing Finasteride Thread.

Ok so I've tried finasteride at a few doses from 0.625 to up to 1.25 ED, EoD or every 3/4 days. For me it doesn't help, I'm getting sexual sides which I'm not going to put up with.

Looked into it and I want to try micro-dosing 0.03/0.04mg to be exact. I have questions though. I know I need to dissolve the pill (1mg each) into a solution. What can I use? Absinth is expensive and other things that have enough alcohol percentage aren't fit for human consumption. Would vodka at 40% work? I just need the pill to dissolve in the liquid and then can mix it with water. deas anyone? I'm from the UK by the way.

Secondly is I'll administer from a syringe or pipette (squirt into my mouth). Can someone help me with the number of amount of liquid needed to get 0.03mg? Ideally each tiny amount would be 0.01mg so I can take 3 and hypothetically up it to 4 if I like to go up to 0.04mg.

Someone please help me out.

I'm more than happy to share my experience as I do this and update progress. I'm just having trouble acquiring the materials needed and doing the maths for dosage correctly.

Thanks everyone!

 

[Afro_Vacancy]

Finasteride dissolves in alcohol apparently, so everclear or high-proof vodka should work.

Dissolve a 5 mg pill of finasteride into an alcohol solution. Make sure you crush the powder really fine. You're really going to have to mortar and pestle that b**ch.

If you take a teaspoon a day out of a 1-litre solution, you will have 0.025 mg/day for 200 days.
If you take a teaspoon a day out of a 750-ml solution, you will have 0.033 mg/day for 150 days.
If you take a teaspoon a day out of a 500-ml solution, you will have 0.050 mg/day for 100 days.

Following this, take photos. Then take more photos six months later, and post them on this forum.

 

[NormanNorwood]

Finasteride dissolves in alcohol apparently, so everclear or high-proof vodka should work.

Dissolve a 5 mg pill of finasteride into an alcohol solution. Make sure you crush the powder really fine. You're really going to have to mortar and pestle that b**ch.

If you take a teaspoon a day out of a 1-litre solution, you will have 0.025 mg/day for 200 days.
If you take a teaspoon a day out of a 750-ml solution, you will have 0.033 mg/day for 150 days.
If you take a teaspoon a day out of a 500-ml solution, you will have 0.050 mg/day for 100 days.

Following this, take photos. Then take more photos six months later, and post them on this forum.

Hey David, good to have you on board

I have a packet of 5mg and a packet of 1mg Finasteride. I will stick to your measurements and use the 5mg. I will look into Everclear (I assume it is safe for human consumption as in swallowing, not just for putting on skin). If not I'll get some Vodka, do you think 40% would do it?

Secondly I have a pestle and mortar at home. Is there no risk of losing some of the Finasteride into the pestle and mortar (I want to be as accurate as possible here)?

Thirdly you said 1x tea spoon a day? How much is a tea spoon? I want to really measure the liquid, not eyeball it with a tea spoon.

I will try and take a photo monthly and will add photos of my hairline before I commence the experiment. Oh and I don't wish to take it daily, I have the scalp and serum DHT levels charts easily viewable and I think once every 3 days or 2x a week will suffice for now.

I will also add that if I start seeing the same sides as before I will quit. I will keep a close eye on these though.

Please help me keep this experiment as accurate as possible

 

[Afro_Vacancy]

1 teaspoon is 4.92892 ml, so 5ml.

I don't know about crushing finasteride, you'll have to google it, it's probably fine. You can always buy liquid finasteride from a pharmacist and dilute it like a homeopath.

I don't know about your mortar and pestle skills, you're probably ok.

The only possible failure mode I can see here is how fine you can crush the powder. It needs to be as fine as possible. Clumps will ruin the experiment, unless clumps dissolve in the vodka.

What you could do is cut a finasteride pill into 4 parts, drop it into a cup of vodka, leave it overnight and see if it's gone the next day. If it is, that means the finasteride does a good job of dissolving by itself and you don't need to be perfect with the mortar and pestle.

Is money an issue for you? You could do everyone a favour by taking a blood test before starting, and 3 months into the experiment.

Finastride in the blood is slow, once every 2 days is fine. However, that measurement does not apply to the skin, which is where your microdosed finasteride will be going. It maybe that 5AR refreshes itself more regularly in the skin. I think that was suggested by polichem.

 

[NormanNorwood]

1 teaspoon is 4.92892 ml, so 5ml.

I don't know about crushing finasteride, you'll have to google it, it's probably fine. You can always buy liquid finasteride from a pharmacist and dilute it like a homeopath.

I don't know about your mortar and pestle skills, you're probably ok.

The only possible failure mode I can see here is how fine you can crush the powder. It needs to be as fine as possible. Clumps will ruin the experiment, unless clumps dissolve in the vodka.

What you could do is cut a finasteride pill into 4 parts, drop it into a cup of vodka, leave it overnight and see if it's gone the next day. If it is, that means the finasteride does a good job of dissolving by itself and you don't need to be perfect with the mortar and pestle.

Is money an issue for you? You could do everyone a favour by taking a blood test before starting, and 3 months into the experiment.

Finastride in the blood is slow, once every 2 days is fine. However, that measurement does not apply to the skin, which is where your microdosed finasteride will be going. It maybe that 5AR refreshes itself more regularly in the skin. I think that was suggested by polichem.

I'll try quartering a 1mg pill and leaving it over night to see how it dissolves. If not pestle and mortar is possible.

Money isn't an issue but I'd like to keep this an affordable endeavour. However I have blood test for something unrelated in September so I will request DHT and Testosterone levels then.

I'd still rather do every three days but if you can show me the policemen study and see information I like about 5ar and skin I will do every 2 days.

 

[NormanNorwood]

Just for reference for anyone else looking at the thread.

There is a gap somewhere between 0.01mg and 0.05 mg where serum/blood DHT isn't too unaffected and scalp DHT is lowered. I estimate this at around 0.03mg which I will try hopefully.

 

[Afro_Vacancy]

Yeah 0.03/0.04 is exactly what I estimated a few weeks ago from the same discussions probably.

The blood tests would be used to confirm that your serum DHT is not or barely affected. It costs different in every jurisdiction.

 

[NormanNorwood]

Yeah 0.03/0.04 is exactly what I estimated a few weeks ago from the same discussions probably.

The blood tests would be used to confirm that your serum DHT is not or barely affected. It costs different in every jurisdiction.

I'm British so I'm pretty sure it will be free on the NHS. I just feel a bit bad requesting this when it's not that I'm ill or anything, just that I'm curious.

By the way your name is quite familiar so I'm starting to suspect that I may have read the same thread haha.

 

[Afro_Vacancy]

I'm British so I'm pretty sure it will be free on the NHS. I just feel a bit bad requesting this when it's not that I'm ill or anything, just that I'm curious.

By the way your name is quite familiar so I'm starting to suspect that I may have read the same thread haha.

Maybe take the first one for free for legitimate reasons, as you benefit from a full baseline regardless.

 

[NormanNorwood]

Maybe take the first one for free for legitimate reasons, as you benefit from a full baseline regardless.

I will think about it over the weekend. I only say this because I am losing hair quite a lot fast, hairline has slowed down for now but I am diffuse thinning (seriously they are everywhere, I'm lucky I had thick hair before this started) like a mother f****r so if I go request a blood test, then wait for the date and then wait for the results it could be a few weeks of hair I lose.

My thyroid test in September which I will request DHT & Testosterone will still show if I'm within normal parameters and that's if I make it that far hoping that sides don't appear again.

Anyway I will try and dissolve a pill over the next couple days and do my best to get ok quality photos of my hair

 

[g.i joey]

didnt studies already establish that at a dosage less than .05 its similar to placebo?

 

[NormanNorwood]

didnt studies already establish that at a dosage less than .05 its similar to placebo?

I think I know the study you're referring at but they tested 0.01mg and found it to be near identical to the placebo group.

The next dosage up was 0.05mg which they discovered inhibited still quite a substantial amount of serum DHT.

They never tested 0.02mg, 0.03mg or 0.04mg.

I'm going to try 0.03mg and see what happens. At the end of the day we can kill the theory and if it works then well maybe it'll help a lot of people who suffer from sides on finasteride in the process

 

[GeorgeNatur]

Obligatory Micro-dosing Finasteride Thread.

Ok so I've tried finasteride at a few doses from 0.625 to up to 1.25 ED, EoD or every 3/4 days. For me it doesn't help, I'm getting sexual sides which I'm not going to put up with.

Looked into it and I want to try micro-dosing 0.03/0.04mg to be exact. I have questions though. I know I need to dissolve the pill (1mg each) into a solution. What can I use? Absinth is expensive and other things that have enough alcohol percentage aren't fit for human consumption. Would vodka at 40% work? I just need the pill to dissolve in the liquid and then can mix it with water. deas anyone? I'm from the UK by the way.

Secondly is I'll administer from a syringe or pipette (squirt into my mouth). Can someone help me with the number of amount of liquid needed to get 0.03mg? Ideally each tiny amount would be 0.01mg so I can take 3 and hypothetically up it to 4 if I like to go up to 0.04mg.

Someone please help me out.

I'm more than happy to share my experience as I do this and update progress. I'm just having trouble acquiring the materials needed and doing the maths for dosage correctly.

Thanks everyone!

Hi Norman,

the fact is that if you have side effects with FINA,
that means your 5Reductase works normal(not overworking) and your DHT levels are normal.

So the Hormone that causes your Hairloss is either high Oestrone or high Estradiol and not the normal levels of DHT.

So you don't need a DHT blocker,
but you need an Oestrone blocker.
(Estradiol is high only if someone has Thyroid problems).

Also if your hair is oily that is an evidence that you have high levels of Oestrone.

If you are going to measure your DHT, you have to measure also your Oestrone.

And a very good natural Oestrone blocker is Grape seed oil ( now foods has good quality).
We have seen miracles with this oil when Oestrone is high(oral use).

Also the use of Pgd2 blockers will solve the Hairloss for ever.

 

[NormanNorwood]

Hi Norman,

the fact is that if you have side effects with FINA,
that means your 5Reductase works normal(not overworking) and your DHT levels are normal.

So the Hormone that causes your Hairloss is either high Oestrone or high Estradiol and not the normal levels of DHT.

So you don't need a DHT blocker,
but you need an Oestrone blocker.
(Estradiol is high only if someone has Thyroid problems).

Also if your hair is oily that is an evidence that you have high levels of Oestrone.

If you are going to measure your DHT, you have to measure also your Oestrone.

And a very good natural Oestrone blocker is Grape seed oil ( now foods has good quality).
We have seen miracles with this oil when Oestrone is high(oral use).

Also the use of Pgd2 blockers will solve the Hairloss for ever.

Hi George.

Well if you're saying is correct then it is nice to know that my DHT and 5Reductase levels are normal.

Maybe you are correct about the Oestrone and Estriadol levels but I was on Finasteride for 3.5 weeks. In that time my scalp itch and shedding completely stopped. I lost only 2 or 3 hairs in the shower. Now 3 weeks off Finasteride I'm shedding so much more again.

My hair is not oily, infact it's probably a little dry due to nizoral shampoo 2/3x a week. However my hair was never too oily, my hair was infact wonderfully thick and healthy. Not too oily or dry so I doubt Oestrone levels are too blame.

As for Estriadol and thyroid. I do not have a thyroid issue as of now, my doctor is keeping an eye on them as they are a tiny bit high but no concern.

I will look into what you have told me but for now because I did mange to stop shedding and itching with Finasteride I would like to try micro-dosing.

Also if Pgd2 blockers stop hairloss forever I think everyone would use them.

Thanks for your message, I will look into your information none the less

Oh and something else I would point out is that thyroid problems do not cause miniaturised hairs.

My hair is falling out receding in a classic male pattern baldness pattern. Thinning at the temples and sides with minituarised hairs only and diffuse thinning at the crown which are also all minituarised hairs.

 

[GeorgeNatur]

Hi George.

Well if you're saying is correct then it is nice to know that my DHT and 5Reductase levels are normal.

Maybe you are correct about the Oestrone and Estriadol levels but I was on Finasteride for 3.5 weeks. In that time my scalp itch and shedding completely stopped. I lost only 2 or 3 hairs in the shower. Now 3 weeks off Finasteride I'm shedding so much more again.

My hair is not oily, infact it's probably a little dry due to nizoral shampoo 2/3x a week. However my hair was never too oily, my hair was infact wonderfully thick and healthy. Not too oily or dry so I doubt Oestrone levels are too blame.

As for Estriadol and thyroid. I do not have a thyroid issue as of now, my doctor is keeping an eye on them as they are a tiny bit high but no concern.

I will look into what you have told me but for now because I did mange to stop shedding and itching with Finasteride I would like to try micro-dosing.

Also if Pgd2 blockers stop hairloss forever I think everyone would use them.

Thanks for your message, I will look into your information none the less

We can understand that if the DHT levels are normal, a DHT blocker will make the levels even lower,
and that will make stop shedding for some months,
but also lower levels(of DHT) from normal are not able to give the Hormone what the body needs to cover his sexual work.

This scenario is very common,
for example Iam sure you can get results by using Revivogen(where are some Pgd2 blockers also).

Shen min I think will help also.

But the better is to measure quickly the Oestrone and DHT,
then you can follow the Cotsarelis Theory (we know is new Theory).

This Theory says that we have to make high levels of Pgd2 normal if we want to stop Hairloss.
And we have to use a PGE2 agonist if we want to regain Hair.

Also a DHT blocker or Oestrone blocker or Estradiol blocker have to be used.

 

[NormanNorwood]

I did look into

We can understand that if the DHT levels are normal, a DHT blocker will make the levels even lower,
and that will make stop shedding for some months,
but also lower levels(of DHT) from normal are not able to give the Hormone what the body needs to cover his sexual work.

This scenario is very common,
for example Iam sure you can get results by using Revivogen(where are some Pgd2 blockers also).

Shen min I think will help also.

But the better is to measure quickly the Oestrone and DHT,
then you can follow the Cotsarelis Theory (we know is new Theory).

This Theory says that we have to make high levels of Pgd2 normal if we want to stop Hairloss.
And we have to use a PGE2 agonist if we want to regain Hair.

Also a DHT blocker or Oestrone blocker or Estradiol blocker have to be used.

I did look at the testosterone/estrogen ratio due to thyroid issues being a cause for hairloss as it can affect conversion of Testosterone into DHT but my thyroid level is high but barely and by barely I mean barely out the normal paramter of what is considered "normal". Nothing that the doctors were concerned by though.

If I had high estrogen which were to send my estrogen/testosterone levels off balance and convert more into DHT I would have symptoms such as higher body fat. I'm 6ft 2 and weigh 70kg. I don't have an ounce of fat on my body.

I also know lowered DHT levels can effect sexual function, this is why I stopped Finasteride the first time. However the reason I am choosing to micro-dose is a study showed that very small doses of Finasteride can reduce scalp DHT levels without dropping serum DHT levels too much thus hopefully side effects.

 

[Afro_Vacancy]

didnt studies already establish that at a dosage less than .05 its similar to placebo?

0.01 mg is similar to placebo, 0.05 mg is much stronger.

 

[stump]

Just for reference for anyone else looking at the thread.

There is a gap somewhere between 0.01mg and 0.05 mg where serum/blood DHT isn't too unaffected and scalp DHT is lowered. I estimate this at around 0.03mg which I will try hopefully.

Okay, serious question. What's the point of microdosing if it inhibits nearly the same exact amount of DHT as 1mg?? DHT inhibition is the cause of the side effects (and hair growth, obviously) you are experiencing. You're inhibiting nearly the same amount of DHT so you'd likely still experience the same exact side effects you had while using the higher dose. The amount you're taking shouldn't matter if the outcome of DHT inhibited is nearly the same.

The only thing I can think of is that with a smaller dose, your DHT would be inhibited for a shorter amount of time, kinda like you are spiking it from low to high and back again.. Your DHT levels would be low for a short period of time, which might explain why you'd get less side effects, but then again I don't see how this would affect your hair loss.

This doesn't make any sense. If the time your DHT is inhibited is independent of the amount you take, then you'd likely still see the same side effects since you're still inhibiting DHT by nearly the same amount. If it's not independent and a smaller dose doesn't inhibit your DHT for long enough then I doubt you'd see any progress in hair growth (and obviously no side effects) since your DHT will just shoot right back up faster than with a larger dose. The only positive to this microdosing that I can see is you'd save money if dosage is independent of the time DHT is inhibited, although Finasteride is dirt cheap to begin with so what's the point?

 

[Afro_Vacancy]

Okay, serious question. What's the point of microdosing if it inhibits nearly the same exact amount of DHT as 1mg?? DHT inhibition is the cause of the side effects (and hair growth, obviously) you are experiencing. You're inhibiting nearly the same amount of DHT so you'd likely still experience the same exact side effects you had while using the higher dose. The amount you're taking shouldn't matter if the outcome of DHT inhibited is nearly the same.

The only thing I can think of is that with a smaller dose, your DHT would be inhibited for a shorter amount of time, kinda like you are spiking it from low to high and back again.. Your DHT levels would be low for a short period of time, which might explain why you'd get less side effects, but then again I don't see how this would affect your hair loss.

This doesn't make any sense. If the time your DHT is inhibited is independent of the amount you take, then you'd likely still see the same side effects since you're still inhibiting DHT by nearly the same amount. If it's not independent and a smaller dose doesn't inhibit your DHT for long enough then I doubt you'd see any progress in hair growth (and obviously no side effects) since your DHT will just shoot right back up faster than with a larger dose. The only positive to this microdosing that I can see is you'd save money if dosage is independent of the time DHT is inhibited, although Finasteride is dirt cheap to begin with so what's the point?

- It might limit the affect that finasteride has on hormones other than scalp and serum DHT, finasteride affects many hormones;
- At 0.03/0.04 mg, scalp DHT will be fully inhibited, but serum DHT will only be partially inhibited.

The time point is irrelevant as the 0.05 mg dose effect, which fully inhibits scalp DHT and only partially inhibits blood DHT, was after a long time baseline.

 

[stump]

- It might limit the affect that finasteride has on hormones other than scalp and serum DHT, finasteride affects many hormones;
- At 0.03/0.04 mg, scalp DHT will be fully inhibited, but serum DHT will only be partially inhibited.

The time point is irrelevant as the 0.05 mg dose effect, which fully inhibits scalp DHT and only partially inhibits blood DHT, was after a long time baseline.

So you're saying the scalp may be more sensitive to Finasteride? Why would that be?