Considering Spironolactone 200 Mg A Day

[InvaderZim]

Hey guys,

I'm considering spironolactone 200 mg a day along with my current regime, which is dutasteride (Avodart) 0.5 mg a day. I'm considering it, because I've read many positive experiences about it taken along with dutasteride. Of course I did reserch about it and I've read all about (possible) side effects. I take full responsibility for myself. When I experience (serious) side effects for a long time, then I will immediately drop the drug. I never experienced side effects with dutasteride so far, so is it safe to say that I won't get side effects from spironolactone? (debunk me if I'm wrong about this idea). I'm doing pretty great with dutasteride 0.5 a day so far, but I'm afraid that my male pattern baldness will become agressive later on, and dutasteride wouldn't be effective anymore. Many guys from my father's side of the family went bald pretty fast at a young age. Also this clinical trial study in Greece gave me some hope: https://www.alopezie.de/diskussion/frauen/uploads/Spironolactone_Study_.htm

Can I just try it and check my blood regularly? What are your thoughts?

 

[InvaderZim]

My dermatologist prescribed it today, but I have to take blood tests as well.

Are there any users who have experiences with spironolactone 200 mg with dutasteride/finasteride?

 

[Retinoid]

If you are doing well with Duasteride with no side effects why do you feel the need to add 200mg of spironolactone...you realize if you just added estrogen you would be on a male to female transgender protocol?

 

[washed_up]

You haven't been on dutasteride for long.

 

[AnxiousAndy]

I agree with @Retinoid. If you are getting results from dutasteride ( which you are ) then there is absolutely no need to add in spironolactone and probably a few extra unwanted side effects! If it means anything to you I was on 150mg - 200mg spironolactone for 6 months and lost a lot of hair that didn't grow back as a result. I know my experience is probably quite rare but its just my 2 cent.

 

[InvaderZim]

I agree with @Retinoid. If you are getting results from dutasteride ( which you are ) then there is absolutely no need to add in spironolactone and probably a few extra unwanted side effects! If it means anything to you I was on 150mg - 200mg spironolactone for 6 months and lost a lot of hair that didn't grow back as a result. I know my experience is probably quite rare but its just my 2 cent.

@Retinoid and you are both right. So far I'm doing great with dutasteride, but I'm afraid that my male pattern baldness will become agressive later on. I will do regularly blood control tests and my dermatologist will let me use it for 3 months (if it gets worse or If I experience serious side effects, then I will drop it immediately).

I think I read somewhere that you were on spironolactone 200 mg ED. Too bad you didn't get desired results from it. Did you took it along with finasteride or other medication? And the hairs you lost, did you regain them back?

 

[InvaderZim]

You haven't been on dutasteride for long.

I'm almost 9 months on it.

 

[Retinoid]

The issue with heavy anti androgen therapy is you cannot really use it forever. The only 'anti androgen' that has been studied in healthy men and for long term use is Finasteride and even this has a whole host of controversy. Duasteride really has not, though we can surmise it probably has a similar safety profile that Finasteride has though possibly not as good. High dose Spironolocatone, Flutamide, Cypro, etc. all have not been studied in depth for healthy men and most likely will negatively impact a lot of bodily functions long term.

 

[AnxiousAndy]

@Retinoid and you are both right. So far I'm doing great with dutasteride, but I'm afraid that my male pattern baldness will become agressive later on. I will do regularly blood control tests and my dermatologist will let me use it for 3 months (if it gets worse or If I experience serious side effects, then I will drop it immediately).

I think I read somewhere that you were on spironolactone 200 mg ED. Too bad you didn't get desired results from it. Did you took it along with finasteride or other medication? And the hairs you lost, did you regain them back?

If dutasteride works it will work for many years, I think you will be fine for the foreseeable future. I took it alongside finasteride and topical spironolactone. For some people spironolactone seems to overcompensate for the lack of binding testosterone and produces more, I feel that was the case for me. Unfortunately most of the hair that shed did not grow back, some did but thinner than before. I feel more comfortable on Cyproterone as it shuts down T at the core and also blocks the androgen receptor, I think it may be slowing down my loss a bit. If you want regrowth maybe add in oral minoxidil, I had a great 4 months on it before it all went to sh*t.

 

[Heinrich Harrer]

One thing I can tell you about spironolactone is it will drop your blood pressure.

 

[InvaderZim]

If dutasteride works it will work for many years, I think you will be fine for the foreseeable future. I took it alongside finasteride and topical spironolactone. For some people spironolactone seems to overcompensate for the lack of binding testosterone and produces more, I feel that was the case for me. Unfortunately most of the hair that shed did not grow back, some did but thinner than before. I feel more comfortable on Cyproterone as it shuts down T at the core and also blocks the androgen receptor, I think it may be slowing down my loss a bit. If you want regrowth maybe add in oral minoxidil, I had a great 4 months on it before it all went to sh*t.

Could you please explain what Cyproterone is? I've heard about it, but don't know a thing about it.

Is oral minoxidil like topical minoxidil?

 

[William Campbell]

Why do you want to turn into a lady?

 

[AnxiousAndy]

Could you please explain what Cyproterone is? I've heard about it, but don't know a thing about it.

Is oral minoxidil like topical minoxidil?

It's a very powerful anti androgen. It shuts down testosterone production in the testes and also blocks the androgen receptors from receiving testosterone and DHT. It can cause gyno and reversible infertility. Its not something I would use If you are getting results from dutasteride, I only ended up using it after exhausting many other options. Oral minoxidil thickens all hairs on your body, not just where you apply it. I've never used topical minoxidil so I can't say much about that, but I do believe oral is a lot more effective.

 

[InvaderZim]

It's a very powerful anti androgen. It shuts down testosterone production in the testes and also blocks the androgen receptors from receiving testosterone and DHT. It can cause gyno and reversible infertility. Its not something I would use If you are getting results from dutasteride, I only ended up using it after exhausting many other options. Oral minoxidil thickens all hairs on your body, not just where you apply it. I've never used topical minoxidil so I can't say much about that, but I do believe oral is a lot more effective.

Thanks man.

Perhaps I will consider oral minoxidil.

 

[InvaderZim]

Why do you want to turn into a lady?

I know this user is a troll, but is spironolactone 200 mg ED (along with dutasteride 0.5 mg ED) really a MTF regimen?

 

[Retinoid]

I know this user is a troll, but is spironolactone 200 mg ED (along with dutasteride 0.5 mg ED) really a MTF regimen?

If you add Estradiol then yes.

 

[InvaderZim]

If you add Estradiol then yes.

What's the function of Estradiol?

 

[Retinoid]

What's the function of Estradiol?

If you need to ask that then you probably should not be taking all these endocrine modulating drugs.

 

[dhtbreaker]

The issue with heavy anti androgen therapy is you cannot really use it forever. The only 'anti androgen' that has been studied in healthy men and for long term use is Finasteride and even this has a whole host of controversy. Duasteride really has not, though we can surmise it probably has a similar safety profile that Finasteride has though possibly not as good. High dose Spironolocatone, Flutamide, Cypro, etc. all have not been studied in depth for healthy men and most likely will negatively impact a lot of bodily functions long term.

I think retinoid is spot on with this...I have seen fantastic regrowth from Spironolactone however these were men transitioning to women! One of them regrew a full head of hair from recession I may add but also her body fat distribution shifted dramtically on breasts, on hips etc be very careful as these great results for hair may come at a price for other areas of your body

 

[InvaderZim]

I think retinoid is spot on with this...I have seen fantastic regrowth from Spironolactone however these were men transitioning to women! One of them regrew a full head of hair from recession I may add but also her body fat distribution shifted dramtically on breasts, on hips etc be very careful as these great results for hair may come at a price for other areas of your body

I understand, but it is only considered HRT if you add Estradiol, according to Retinold.

What about this study in Greece? https://www.alopezie.de/diskussion/frauen/uploads/Spironolactone_Study_.htm

Surely those two men and two women weren't transsexuals in transition.