Dr. Tsuji Kyocera, Riken Research, Organ Technologies Form Regenerative Hair Research Team

[Solomon]

Lol I had the same reaction, who knows where Forbes got that number from.

FWIW I believe that article that stated the $800-$1000 figure said that's where it would start.

This article is written very unprofessional.
100 000 yen is 956 usd

 

[JLC]

This is great news and if the Brotzu lotion doesn't work I'll definitely use this.

On the downside 4-7 years is a very long way off.
And also I've not seen one single hair transplant ever that looks perfect, it always looks a bit off the mark at best. So this isn't a full 100% cure, as in returning your hair to exactly as it was before hair loss.

But overall I'm very happy to hear this news.

 

[Xaser94]

This is great news. If we can confirm weather the trials start in 2020, or they begin commercialization by 2020 Im sure that would ease alot of people's worry about time lines. We already know Japan only needs up to phase 2.

I honestly dont think people need to worry about not enough clinics offering treatment or huge waiting lists tbh. I think hair loss sufferers on the forums grossly overestimate how much people are willing to do something about baldness that is more than maybe a topical application they can grab over the counter at CVS for a couple months. That would be the most ideal situation for most people I think, including me.

Alot of older men have come to terms with their balding, have kids and a wife, and would really have to consider weather the price is worth it and what it would add to their lives at this point. Helping children with their college fund or paying off their house may seem as the more attractive option than having more hair.

People in there early 20's who are just starting to bald will probably be able to get other treatments that will be out by 2020 not having to go to Japan at all. Seeing as this seems more benifical to those really far gone with higher norwoods, it would be stupid for a norwood 2 to go all the way to Japan for a hair transplant with cloned follicles if histogen, samumed, or even brotzus lotion gets you back to Norwood 1. And even if they wanted cloned hair follicles, most younger men probably wouldnt have the financial means to go to Japan anyway to get the procedure. As a struggling college student, me and alot of kids coming out with student debt simply wont be able to afford it.

People on the forums are are very passionate about the matter and a vocal minority, including me, and I think those are the people who will be the early adopters. This vocal minority I think makes it seem like more people would actually be early adopters but out in the real world I see alot of balding/bald people pretty happy with where there lives are. Would they like their hair back? Probably. But i think they would weigh out the benefit and convenience more than you and I would.

I think it would gradually become main stream, and they'll probably scale proportionately to the increase in demand. I highly doubt overnight they're will be millions of people making appointments. I also think they're will be enough clinics in Japan as whole lot more may open up just to cater to medical tourism, but proportionately to the demand, not more, not less. Eventually I see it being so main stream it would be just like getting braces or some botox however if nothing more convenient halts hair loss/regrows.

Lastly, as much as this seems like the silver bullet/light at the end of the tunnel, and Im super excited, it seems like people really do have different standards for news. Where as one treatment can have shown efficacy on mice and its shunned completely while this also has only been proven only on mice and is considered the holy grail. I understand the weight of the researchers and money behind it makes it more credible/not being a snake oil, but does it really increase the probability it will work on humans vs any other treatment? This is a question Im actually asking btw lol, not tryna say anything negative about anyone.

I hope this is released in 2020, works on humans, and before we reach the light at the end of the tunnel histogen or brotzus lotion can be our torch to safely get us to there still in one piece!

 

[resu]

Histogen is too little and too late, if Folica and the Italian lotion come out that should hold the fort until this comes out.

 

[Xaser94]

Histogen is too little and too late, if Folica and the Italian lotion come out that should hold the fort until this comes out.

Isnt Histogen and Follica coming out at the same time? By 2018? But yeah sure, I meant whatever treatment that is available by then. I forgot Follica, my apologies.

 

[resu]

Isnt Histogen and Follica coming out at the same time? By 2018? But yeah sure, I meant whatever treatment that is available by then. I forgot Follica, my apologies.

Last I checked Histogen were still trying to get funding which they did by the way.
http://www.hairlosscure2020.com/histogen-and-replicel-updates/

 

[Pray The Bald Away]

Great news. At 29, I'm skeptical this will have much of an impact on me, though - hope some of the other pipeline treatments will be good in the interim.

Also, I can't get overly excited until Shiseido starts their trials -I know the Tsuji trials are likely years away, but the bureaucratic delays Replicel's facing have me wondering when the "accelerated" process will actually be in full swing. Nonetheless, great news for younger folks.

RIKEN is a government funded institution. As shady as it sounds, I don't think they'll face the same bureaucracy as a company wholly in the private sector.

 

[Pray The Bald Away]

This is great news. If we can confirm weather the trials start in 2020, or they begin commercialization by 2020 Im sure that would ease alot of people's worry about time lines. We already know Japan only needs up to phase 2.

I honestly dont think people need to worry about not enough clinics offering treatment or huge waiting lists tbh. I think hair loss sufferers on the forums grossly overestimate how much people are willing to do something about baldness that is more than maybe a topical application they can grab over the counter at CVS for a couple months. That would be the most ideal situation for most people I think, including me.

Alot of older men have come to terms with their balding, have kids and a wife, and would really have to consider weather the price is worth it and what it would add to their lives at this point. Helping children with their college fund or paying off their house may seem as the more attractive option than having more hair.

People in there early 20's who are just starting to bald will probably be able to get other treatments that will be out by 2020 not having to go to Japan at all. Seeing as this seems more benifical to those really far gone with higher norwoods, it would be stupid for a norwood 2 to go all the way to Japan for a hair transplant with cloned follicles if histogen, samumed, or even brotzus lotion gets you back to Norwood 1. And even if they wanted cloned hair follicles, most younger men probably wouldnt have the financial means to go to Japan anyway to get the procedure. As a struggling college student, me and alot of kids coming out with student debt simply wont be able to afford it.

People on the forums are are very passionate about the matter and a vocal minority, including me, and I think those are the people who will be the early adopters. This vocal minority I think makes it seem like more people would actually be early adopters but out in the real world I see alot of balding/bald people pretty happy with where there lives are. Would they like their hair back? Probably. But i think they would weigh out the benefit and convenience more than you and I would.

I think it would gradually become main stream, and they'll probably scale proportionately to the increase in demand. I highly doubt overnight they're will be millions of people making appointments. I also think they're will be enough clinics in Japan as whole lot more may open up just to cater to medical tourism, but proportionately to the demand, not more, not less. Eventually I see it being so main stream it would be just like getting braces or some botox however if nothing more convenient halts hair loss/regrows.

Lastly, as much as this seems like the silver bullet/light at the end of the tunnel, and Im super excited, it seems like people really do have different standards for news. Where as one treatment can have shown efficacy on mice and its shunned completely while this also has only been proven only on mice and is considered the holy grail. I understand the weight of the researchers and money behind it makes it more credible/not being a snake oil, but does it really increase the probability it will work on humans vs any other treatment? This is a question Im actually asking btw lol, not tryna say anything negative about anyone.

I hope this is released in 2020, works on humans, and before we reach the light at the end of the tunnel histogen or brotzus lotion can be our torch to safely get us to there still in one piece!

Colin Jahoda proved it works in humans by cloning a hair onto his wife's arm. He's the one who started all this.

 

[Torin]

Good post Xaser94.

I also hope that Brotzu's lotion would suffice especially if it works way better than minoxidil.

However if it doesn't grow back sufficient cosmetic hairs then clearly the only solution for all levels of hair loss from NW2 to NW7 will be cloning.

As far as I'm concerned, what Riken is attempting to do represents a de facto cure for us. If it can look like really dense, unlimited hair transplant without ugly scarring, well I think that is way beyond perfect. That is what we all want.

If you think about it, even fue is an incredible procedure but one with too many drawbacks, most notably scarring and limited hair grafts. With cloning the scar will be minimal and we'll have all the hair we want (like original density).

Gene editting or whatever has never really been on the cards. It's just too far off at this time and has too many ethnical issues around it.

But really that's not an issue for us. This cloning technology that we that really started in the 80s and 90s is coming to bear fruit now. I'm glad that we have the brilliant and visionary Dr.Tsuji harnessing today's cutting edge technology to develop this hair regeneration system.

 

[Desmond_84]

First of all WOW
Tsuji is finally delivering on his words. I can't believe it. The next few years is going to be exciting times to be alive. We are finally going to end the one thing that ages men the most and prematurely most of the times actually.

On a second note though, has Tsuji cracked the DP replication problem and hasn't published it just to keep it away from competitors. He must have shown unpublished data to Kyocera for them to drop loads of cash at his feet.

God please let this work out.....fingers triple crossed.

 

[Swoop]

Lastly, as much as this seems like the silver bullet/light at the end of the tunnel, and Im super excited, it seems like people really do have different standards for news. Where as one treatment can have shown efficacy on mice and its shunned completely while this also has only been proven only on mice and is considered the holy grail. I understand the weight of the researchers and money behind it makes it more credible/not being a snake oil, but does it really increase the probability it will work on humans vs any other treatment? This is a question Im actually asking btw lol, not tryna say anything negative about anyone.

You need to look at the science behind a method and relate to observations as much as possible. That might give you a predictable measurement of success, nothing else pretty much will.

Read up on mesenchymal-epithelial interactions of de novo hair follicle formation... There are many studies about this.

Here is one study for example from Rendl;

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1216328/

[De novo hair follicle formation in embryonic skin and new hair growth in adult skin are initiated when specialized mesenchymal dermal papilla (DP) cells send cues to multipotent epithelial stem cells. Subsequently, DP cells are enveloped by epithelial stem cell progeny and other cell types to form a niche orchestrating hair growth.

This is pretty much exactly what Dr. Tsuji is trying to do. There was always the problem of losing signature expression when culturing DP cells, but it seems Dr. Tsuji has just fixed this. Not only this, I assume has has found a way to culture the epithelial stem cells too now, which was what he was struggling with. So in a sense he puts those cells together in vitro to mimic the observations that happen in the embryonic window. That should give rise to a primordium and when injected/implanted should grow into a fully developed hair follicle.

A illustration of what Dr. Tsuji is trying to do can be seen in the following movie check until minute 8, all about Dr. Tsuji;

 

[Joxy]

Guys, don’t be naive. Tsuji will do preclinical trials to see if his method work or not. This are not official clinical trials, so probably they either don’t know if this treatment work or not on humans.

We are still many, many years away from treatment.

 

[whatevr]

OK so basically from what I understand there is still grafting involved, but not of whole hair follicles but of hair follicle "germs"? Will this allow denser packing than typical FUE? It still requires hours of surgery though doesn't it?

 

[kuba197]

So maybe Admin sholud contact with Tsuji and ask our questions.

 

[Blackber]

You need to look at the science behind a method and relate to observations as much as possible. That might give you a predictable measurement of success, nothing else pretty much will.

Read up on mesenchymal-epithelial interactions of de novo hair follicle formation... There are many studies about this.

Here is one study for example from Rendl;

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1216328/



This is pretty much exactly what Dr. Tsuji is trying to do. There was always the problem of losing signature expression when culturing DP cells, but it seems Dr. Tsuji has just fixed this. Not only this, I assume has has found a way to culture the epithelial stem cells too now, which was what he was struggling with. So in a sense he puts those cells together in vitro to mimic the observations that happen in the embryonic window. That should give rise to a primordium and when injected/implanted should grow into a fully developed hair follicle.

A illustration of what Dr. Tsuji is trying to do can be seen in the following movie check until minute 8, all about Dr. Tsuji;

If they are injecting follicle "germs" do you have any idea how they will control the angle of hair growth?

Maybe that where Kyocera comes in with the tech they plan to develop....

 

[DDobler]

I think I am missing something please make some order in my head:
It sounds good and everyone is happy - but, as for yesterday - wasn't it impossible to clone terminal hairs? Wasn't it a science fiction? Something that according to our talks is 10-15 years away? A thing that DR.Lauster team worked on and failed or something?
Everyone here are so happy, but how do we know that it even works? Do they have something in their hands already? I mean, no clinical trials were ever made.

 

[hellouser]

I think I am missing something please make some order in my head:
It sounds good and everyone is happy - but, as for yesterday - wasn't it impossible to clone terminal hairs? Wasn't it a science fiction? Something that according to our talks is 10-15 years away? A thing that DR.Lauster team worked on and failed or something?
Everyone here are so happy, but how do we know that it even works? Do they have something in their hands already? I mean, no clinical trials were ever made.

Think of it as an inverted bell curve... all the progress we had 10 years ago was peanuts compared to what we have today, but all of it is rapidly moving forward... at some point in the very near future, we're going to strike gold; it's inevitable.

 

[Pray The Bald Away]

Think of it as an inverted bell curve... all the progress we had 10 years ago was peanuts compared to what we have today, but all of it is rapidly moving forward... at some point in the very near future, we're going to strike gold; it's inevitable.

I'd argue we've already struck gold. We're just waiting to deposit it into our accounts. Just think, we're all going to have Ronald Reagan levels of hair thickness into old age!

 

[Thespain]

Just when I had hit rock bottom, something promising to look forward to. A light at the end of the tunnel. I really hope things work out smoothly.

Is this hair going to be DHT resistant? Propecia is a real b**ch to take every day.

 

[kuba197]

Just when I had hit rock bottom, something promising to look forward to. A light at the end of the tunnel. I really hope things work out smoothly.

Is this hair going to be DHT resistant? Propecia is a real b**ch to take every day.

Thats the hole trick man. Dht resistant hair. They have the same gene expression like your hair from the back.