Exploring The Hormonal Route. Hair=life.

Adri23

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keep goign with corticosteroids immune system is linked to hair too and not only in areata.However clobetasol 3 times a week its excessive cause its one of the most potent corticosteroids.
Ye I have been reading studies and 1 per week is enough, maximum twice of the scalp is too bad but not for too long. It is indeed the most potent one according to wiki.
 
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Almas_NW0

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View attachment 164430
The first injection today, estradiol enanthate 0.31ml (15mg estradiol), in 2 weeks I will be tested for hormone levels.
To be honest, I am looking forward to changes in my body with great fear. The most desperate act of my life
I made the first injection. It's not scary at all, I didn't even feel anything, lol. Only my needles are too thin, I did not inject the entire dose completely, so I had to give a second injection to inject the right dose.
I don’t believe I’m doing this.
UPD: The second injection was painful. I have little experience, so I made mistakes.
:)
 

sg2000

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@Adri23 tbh the only chaange i will do to my regimen is increasing dutasteride dose from 0.5 straight to 2.5 mg.When im going to get a job a will take 5 capsules of avodart a day.It will cost me a lot but i dont care at all.It will cost me 135 euro monthly of dutasteride lol
 

Adri23

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@Adri23 tbh the only chaange i will do to my regimen is increasing dutasteride dose from 0.5 straight to 2.5 mg.When im going to get a job a will take 5 capsules of avodart a day.It will cost me a lot but i dont care at all.It will cost me 135 euro monthly of dutasteride lol
That's good. I will try and see if my powder works. If I get my dht to very low levels I will call it a success tbh. Either way 2.5 mg should be the correct dosage for aggressive balding (people that cant stop their hair loss with hrt and normal dosages of bic/dutasteride)
 

sg2000

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That's good. I will try and see if my powder works. If I get my dht to very low levels I will call it a success tbh. Either way 2.5 mg should be the correct dosage for aggressive balding (people that cant stop their hair loss with hrt and normal dosages of bic/dutasteride)
dont you think that nuking T and gurther dht with hrt can lower scalp dht itself?Its impossible that i would not reduce it
 

Adri23

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dont you think that nuking T and gurther dht with hrt can lower scalp dht itself?Its impossible that i would not reduce it
You would need a genetic test to see if your 5ar1 is very active or not. I got mine and showed 5ar1 is equally active as 5ar2. Some ppl say 5ar1 does not produce baldness but I would be skeptical tbh. I rly think for aggressive balding ppl every androgen makes us bald no matter which one, just at different speed
 
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Adri23

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BTW guys if anyone is gonna try this experiment if mine success(hopefully it will since im doing everything right) you have to buy MCT oil specifically, DO NOT buy regular coconut oil thinking you could save money and it is the same cause it is not. It would destroy your solution and ethanol would separate from the oil and you wont be taking dutas most days or you would take different dosages every day. So for a clean solution ALWAYS buy MCT oil. Choosing the right oil is what will give you a good, bioavailable and clean solution.

Also you shouldn't use other oils cause they are long chain fatty acid and your ethanol will precipitate. So please stick with MCT oil specifically and if you can, try to get MCT C8 only which would bring the best miscibility in alcohol

 

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sg2000

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BTW guys if anyone is gonna try this experiment if mine success(hopefully it will since im doing everything right) you have to buy MCT oil specifically, DO NOT buy regular coconut oil thinking you could save money and it is the same cause it is not. It would destroy your solution and ethanol would separate from the oil and you wont be taking dutas most days or you would take different dosages every day. So for a clean solution ALWAYS buy MCT oil. Choosing the right oil is what will give you a good, bioavailable and clean solution.

Also you shouldn't use other oils cause they are long chain fatty acid and your ethanol will precipitate. So please stick with MCT oil specifically and if you can, try to get MCT C8 only which would bring the best miscibility in alcohol

i cant wait to see your blood test bro
 

Adri23

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i cant wait to see your blood test bro
I hope it works. Everything is on point if it doesnt work idk what to do anymore
 
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sg2000

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If it works in reducing dht dont mess things up or maybe you’ll require higher and higher dose to suppress dht (?)
 

sg2000

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I hope it works. Everything is on point if it doesnt work idk what to do anymore
just continue with your regimen and high dose dutasteride a corticosteroid and keep your hair for the rest of your life.
You chose to marry hair aand love them for the rest of your lifee
 

Adri23

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If it works in reducing dht dont mess things up or maybe you’ll require higher and higher dose to suppress dht (?)
No I will keep my % ethanol to mct oil ratio and the mg/ml of dutas to ethanol because that is what worked after some experimentation. If I increase the % ethanol to mct oil ratio my solution could precipitate, and if I increase my mg/ml of dutasteride to ethanol it can precipitate too, so I will keep the balance I have right now despite having to use 6 ml of solution per day and wasting more capsules and oil, but anyways the oil is like 49.5€ and last 6 months so the oil would cost just ~8.25€ per month which is very cheap. Capsules are also cheap so there is no problem with that. Only 'issue' is that I have to use many of them (~6 capsules per day if you use 00 size capsules) but for 8.5 mg of dutasteride 6 capsules are not many if you ask me( you would need to use 17 capsules of Avodart if you attempted to take that many mg of dutasteride)
 
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Adri23

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If it works in reducing dht dont mess things up or maybe you’ll require higher and higher dose to suppress dht (?)
That shouldnt happen in theory cause dutasteride irreversibly inhibit 5ar while you are taking the drug. The reason why my dht might have rised could be an upregulation in 5ar1. dutasteride 0.5 mg or 1 mg cover some of 5ar1 (about 50% for 0.5 mg, maybe 55% for 1 mg but this one is not official) so as you can see there is half more of 5ar1 intact. In theory if 5ar1 upregulates due to heavy androgen deprivation the other half of 5ar1 could be upregulated(all these are not proven theory). But when you take very high dosages (+2.5 mg per day) there is no way your body could upregulate anything because as I said dutasteride irreversibly inhibit 5ar while taking it so the body would have no 5ar to upregulate anymore(maybe there is some but too low to have an impact when you take dosages of +5 mg per day)
 

BeardCombover

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@BeardCombover do you think that in case i drop cpa completely or ill reduce dosage over time T or DHT could spike without changing e2 dose?
CPA is very complex, so yes, they could, for one reason or another. That's why you always need clear endplan before messing with your regime, as well as patience, to avoid dangling around like a poop in an ice hole.
If you plan to replace CPA with Bica, i think you can do it cold turkey, but you need a loading dose of Bica. So 50mg Bica for first week, than 25mg for a week or two, than you can try lowering it even further.
If you plan to drop AAs in general, you need to taper off CPA really slooow. So first you go 12.5mg EOD for a week, than every 2 day for a week or two, than every 3 day. That should be enough.
Also, as I already mentioned, 12mg/10d E is unreasonably high, 10mg is more than enough and 11mg is max. Guess you can fix it when your hair stabilize, but too high of a dose can cause issues by itself (mainly prolactin).
Im on vacation btw, so gonna be off for some time.
 

sg2000

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however im taking a really low dose in theory 75 mg a week(10 mg a day) i could take this dosage for a week then 50 mg a week and after 2 weeks,a 25 a week and then not taking it anymore
 
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