Exploring The Hormonal Route. Hair=life.

[Esquire Janey]

Sad thing is, Estradiol is pro-inflammatory too.
The 6 new findings suggest pro-inflammatory action with all being positively associated with circulating estradiol: serum amyloid P (SAP), soluble IL-1 receptor 2 (sIL-1RII), resistin, chemokine (C–C motif) ligand-21 (CCL21), basic fibroblast growth factor (FGF2), and IL-6
That's one of the reasons why taking progestins help some women with thinning, cause they mediate inflammatory effects of estrogen domination.
Overall, im pretty sure that inflammation is the main cause of any hairloss, because its a predecessor of every disorder from hair cycle disruption to any autoimmune disorder (fungal, viruses, allergies, you name it).
The difference between male and female hairloss is basically that women need PCOS to make a lot of andogens, and men make them by default. The other minor difference is skull anatomy, because of it women are more prone to diffuse thinning.
Other causes are the same for both: CAH and ncCAH, Prolactin, Estrogens (as mentioned above), stress, digestive issues/bad diet, and, in some cases, gene mutations.

PCOS is a tough nut to crack. Progesterone and its use seems to be almost indecipherable based upon my last wiki perusal. I never find anything substantive enough to latch onto at least in terms of the most "successful" transition possible that would come from P4 but cis-women might be different. I use P4 now but switched to taking it orally. I think it is largely likely to do nothing for hair growth and it might harm it.

I also doubt that it is necessary for the best breast growth for those seeking that feature. Even during pregnancy when I look at the entries it is obscure exactly what P4 is doing or causing. Is it used in IVF?

 

[sg2000]

You ever did a scalp biopsy? I think I will do one soon because I really suspect this diffuse thinning coming from auto immune disease

no i didnt. It could be some diffuse alopecia areata that could be mistaken for Androgenetic Alopecia but again im using topical corticosteroid so im fine

 

[sg2000]

@BRezende can you show me a photo of your diffuse thinning in dm so we can compare to each other

 

[Esquire Janey]

no i didnt. It could be some diffuse alopecia areata that could be mistaken for Androgenetic Alopecia but again im using topical corticosteroid so im fine

<rolls eyes>. You need to use the hair you have and not repine over a future that is likely never to come.

 

[Esquire Janey]

My hair looks particularly good today, just the hair cut is a bit if a mess ngl. Higher dosages dutasteride rly did change everything. minoxidil gave me hairline gains but dutasteride at higher than standard dosages improved the diffuse, thickness and overall hair quality.

I don't see any baldness at all. Presumably you are hormonally female.

 

[Adri23]

I don't see any baldness at all. Presumably you are hormonally female.

My hair was worse months ago. Pre hrt I was balding so fast even with dutasteride and oral minoxidil. Only hrt improved my hair but always with the help of dutasteride, minoxidil and possibly bica. Only estradiol would never help my hair loss because my genetic still produce a lot of DHT even without testosterone

 

[sg2000]

 

[Esquire Janey]

My hair was worse months ago. Pre hrt I was balding so fast even with dutasteride and oral minoxidil. Only hrt improved my hair but always with the help of dutasteride, minoxidil and possibly bica. Only estradiol would never help my hair loss because my genetic still produce a lot of DHT even without testosterone

Are you living as a female?

 

[sg2000]

 

[Adri23]

First pic was my hair when I was 21 yo. Pre dutasteride and pre minoxidil. I was balding so bad, but that was happening since I had 16 but it speeded up at 19. Second pic after 6 months HRT. My hair was still bad but kinda better, I think CPA was making me not gain much hair since it raised my DHEA-S and my DHT was still super high which I think it was being converting by backdoor pathways. I was taking dutasteride by that time but 0.5 mg does nothing to me

Compare it with this

Btw I didnt mean to do a 5 month update but I was bored today and decided to read this thread from November to now to see if I could find any pic from 6 months ago. It seems like my hair has improved a lot in the last 5 months wtf!?

Or this

My hair looks particularly good today, just the hair cut is a bit if a mess ngl. Higher dosages dutasteride rly did change everything. minoxidil gave me hairline gains but dutasteride at higher than standard dosages improved the diffuse, thickness and overall hair quality.

 

[sg2000]

this is my diffuse thinning…
@BRezende @Adri23 @BeardCombover
do you think it could be an autoimmune disease or some Telogen Effluvium or CTE?

 

[Adri23]

Are you living as a female?

No. Even after 3 years no one suspect i take estradiol. I still have a male face just with better skin and hair and some changes in the eye area.

 

[Esquire Janey]

My hair was worse months ago. Pre hrt I was balding so fast even with dutasteride and oral minoxidil. Only hrt improved my hair but always with the help of dutasteride, minoxidil and possibly bica. Only estradiol would never help my hair loss because my genetic still produce a lot of DHT even without testosterone

I always wanted to try Bica but my doctors are not comfortable prescribing it even though they continue to dispense Premarin.<rolls eyes>

 

[Adri23]

this is my diffuse thinning…
@BRezende @Adri23 @BeardCombover
do you think it could be an autoimmune disease or some Telogen Effluvium or CTE?

Used to have that with CPA. Could even be prolactin issues ngl. Have you done prolactin blood test? I rly hated CPA

 

[Adri23]

I always wanted to try Bica but my doctors are not comfortable prescribing it even though they continue to dispense Premarin.<rolls eyes>

You can buy on hrt caffe without issues.

 

[Esquire Janey]

No. Even after 3 years no one suspect i take estradiol. I still have a male face just with better skin and hair and some changes in the eye area.

Nothing below the neck? You are young though. I see distinctive female changes to your face from the male norm even if I cannot articulate exactly what leads me to the conclusion.

 

[sg2000]

Used to have that with CPA. Could even be prolactin issues ngl. Have you done prolactin blood test? I rly hated CPA

my latest blood test showed 85 prolactin and i was taking 100 mg a week

 

[Esquire Janey]

You can buy on hrt caffe without issues.

I have had trouble getting things because Amazing 4 Health stopped taking PayPal. I had to send a check to India to get knock-off Estogel as they spell it.

 

[Esquire Janey]

my latest blood test showed 85 prolactin and i was taking 100 mg a week

Once you go down the prolactin-following road, all is lost in terms of OCD<smiles gently>

 

[Adri23]

Nothing below the neck? You are young though.

Yes breast growth but only tissue cause I am extremely skinny. Weight 57.4 kg and my height is 180 cm so yeah 0 fat or muscle cause I dont work out