Exploring The Hormonal Route. Hair=life.

[Hair We Go Go]

@John Difool

Hi, Ive just read your post on the previous page regarding the DHT back door pathway and the use of Abiraterone Acetate - where one source this at a reasonable price?

I've found it on the website below - but it's literally the same price as a hair transplant in Turkey.


Are there any other drugs that can stop this back door action?

 

[JaneyElizabeth]

Oral Minoxidil study:

Efficacy and Safety of Oral Minoxidil 5 mg Once Daily in the Treatment of Male Patients with Androgenetic Alopecia: An Open-Label and Global Photographic Assessment - Dermatology and Therapy

Introduction Oral minoxidil is an antihypertensive vasodilator known to stimulate hair growth. The use of low-dose oral minoxidil for the treatment of male androgenetic alopecia (Androgenetic Alopecia) is receiving increasing attention. The aim of this study was to evaluate the efficacy and safety of oral...

link.springer.com

 

[JaneyElizabeth]

Early or semi-early Selleck:

Watch Runaway (1984) | Prime Video

In the near future, a police officer specializes in malfunctioning robots. When a robot turns out to have been programmed to kill, he begins to uncover a homicidal plot to create killer robots... and his son becomes a target.

www.amazon.com

 

[John Difool]

@John Difool

Hi, Ive just read your post on the previous page regarding the DHT back door pathway and the use of Abiraterone Acetate - where one source this at a reasonable price?

I've found it on the website below - but it's literally the same price as a hair transplant in Turkey.

Zelgor (Abiraterone) - 250mg (120 Tablets) - United Pharmacies (UK)

Zelgor (Abiraterone) is a treatment for prostate cancer that is resistant to hormonal or surgical treatment, otherwise known as Metastatic Castration-Resistant Prostate Cancer (mCRPC). Abiraterone needs to be taken in conjunction with prednisone.

www.unitedpharmacies-uk.md

Are there any other drugs that can stop this back door action?

Talk to any pharmas owners in China India Russia. If they don't have it yet they can order it for you. Another place is Hong Kong. I can't be specific because it's not legally the right place for that.

 

[JaneyElizabeth]

Talk to any pharmas owners in China India Russia. If they don't have it yet they can order it for you. Another place is Hong Kong. I can't be specific because it's not legally the right place for that.

How about including your knowledge related to what she is talking about and whether that has anything to do with HrT and hair loss. That's one that I don't know about, loathe as I am to admit it.

 

[John Difool]

Sorry, who is "she"?

 

[Hair We Go Go]

Me? I am she. I should really change my PP to my actual face, sorry.
I'm still trying to recover my temples and get that NW0 I've tried all of the usual 'front' door methods. Just curious about the back door. I guess I need to test my 3a androstanediol glucuronide levels to see if I really do have that problem. I've been on Bica & Oral min pretty much all year (Powers states that Bica will fix the back door issue) but it hasnt in my case as my hair is worse now than in Feb 2020. Reading what John wrote a few pages back it could be that Bica cases a degree of masculinization over time? I'm not sure if that's from t receptors going mutant (if that's a thing) or just from the free T?
Sorry I'm just thinking out loud here. Just planning a way forward. I'll prob also lower and phase out Bica and get back on CPA.

Has anyone actually had success with Bica & hairline recovery?

 

[Hair We Go Go]

The gal who asked the question but it's okay, lol, I have lost interest. I find that post to be strange to begin with. Cheers.

Err pot-calling-the-kettle-black?

 

[Hair We Go Go]

Never mind, I thought I could come here and discuss hair (gourmetstylewellness.com after all) - it's ok I'll just carry on figuring things out on my own.

Bye

*@Noah looking great BTW!!

 

[Gergely]

i’m coming to the end of a 3 month Telogen Effluvium shed, it’s beginning to fill back in.

i wish i had your hairline right now i have a 5head

 

[Hair We Go Go]

Prior to my stint on Bica I was on 50mg CPA (yeah I know, too much) during this time I grew quite a few pigmented vellus, maybe a few terminal hairs too in my temple area. My temples have been slick bald for 26years. After switching to Bica the hairs disappeared and have been replaced with standard colourless vellus (max 1cm long)
I'm going to switch back to CPA (12.5mg this time) and apply some bimatoprost to the scalp with topical minoxidil & tretinoin once it arrives. To coax those terrible vellus hairs into action.
I do have low T (tested recently - pictured) I really don't know what's going on with me, perhaps I do have a backdoor pathway issue, maybe my 200mg P4 is turning directly into DHT ...I should have got a DHT test too.
I'm wondering if I have a other type of hairless perhaps like FFA ??
-anyway that's me... a hair loss mess.

 

[Gergely]

Are you still on all the medications listed in your regimen ?

i switched from 4mg E to 100mg progesterone and 2mg E ten days ago

 

[Hair We Go Go]

Thanks Noah that's useful.
CPA also causes adrenal insufficiency, perhaps this helps too - idk? Squeeze that T... Maybe I should also add spironolactone to help with this effect?? Lol... 0T

@Janey - The back door thing I keep refering too is the alternative pathways to DHT that might not be blocked with just an 5ari

 

[JaneyElizabeth]

Me? I am she. I should really change my PP to my actual face, sorry.
I'm still trying to recover my temples and get that NW0 I've tried all of the usual 'front' door methods. Just curious about the back door. I guess I need to test my 3a androstanediol glucuronide levels to see if I really do have that problem. I've been on Bica & Oral min pretty much all year (Powers states that Bica will fix the back door issue) but it hasnt in my case as my hair is worse now than in Feb 2020. Reading what John wrote a few pages back it could be that Bica cases a degree of masculinization over time? I'm not sure if that's from t receptors going mutant (if that's a thing) or just from the free T?
Sorry I'm just thinking out loud here. Just planning a way forward. I'll prob also lower and phase out Bica and get back on CPA.

Has anyone actually had success with Bica & hairline recovery

Welcome. I thought, well you hear a lot of back door jokes. I am interested in helping folks who are "stalled" as long as we aren't talking about breast stalls and I think that unlike in the case of MtFs, we don't have a lot of years of cis-guys trying to restore hair loss on hormones. The crux right now in my mind seems to be E levels but you might have perfect E and T levels as a female and still not progressing. Many MtFs continue to get hair transplants which is something that as a previous diffuse thinner, I am not considering,

 

[JaneyElizabeth]

Me? I am she. I should really change my PP to my actual face, sorry.
I'm still trying to recover my temples and get that NW0 I've tried all of the usual 'front' door methods. Just curious about the back door. I guess I need to test my 3a androstanediol glucuronide levels to see if I really do have that problem. I've been on Bica & Oral min pretty much all year (Powers states that Bica will fix the back door issue) but it hasnt in my case as my hair is worse now than in Feb 2020. Reading what John wrote a few pages back it could be that Bica cases a degree of masculinization over time? I'm not sure if that's from t receptors going mutant (if that's a thing) or just from the free T?
Sorry I'm just thinking out loud here. Just planning a way forward. I'll prob also lower and phase out Bica and get back on CPA.

Has anyone actually had success with Bica & hairline recovery?

@bridgeburn did but he had success with all of the big three AA's seemingly. Many of us have had sheds either when adding an AA or going off one as I have gone through the thread.

 

[JaneyElizabeth]

i’m coming to the end of a 3 month Telogen Effluvium shed, it’s beginning to fill back in.

View attachment 149157

I can't tell but have you had sort of a back and forth battle with sheds? Your hair recalls a young Rob Lowe so I hope you are enjoying the high points. Rob Lowe is maybe third in my mind after Brad Pitt and Jeff Bridges.

 

[JaneyElizabeth]

i wish i had your hairline right now i have a 5head

You hair line in your avatar is like what I call anchorman hair. Often they seem to have perfect hair except for substantial corner loss in the temples that is still not unattractive like Peter Jennings, Tom Brocaw, Jeff Daniels in the Newsroom and others. Sting had hair like this for ages. It seems not to interfere with growing hair long but the corner loss can add an illusion of wisdom and maturity.

 

[JaneyElizabeth]

Thanks Noah that's useful.
CPA also causes adrenal insufficiency, perhaps this helps too - idk? Squeeze that T... Maybe I should also add spironolactone to help with this effect?? Lol... 0T

@Janey - The back door thing I keep refering too is the alternative pathways to DHT that might not be blocked with just an 5ari

I gotcha. I usually have been referring to that as DHT synthesization but more so with respect to tissue. I am semi-convinced that beard removal destroys the backdoor pathways in the face related to beard growth. I am also wondering if they might be signalling between tissue that is known to suffer from DHT effects primarily, meaning above the neck. I have had a completely different feminization story below the neck which came easy and without my ever worrying about it and above the neck, where facial feminization and hair growth were lagging. At the time that my breasts were all but fully formed, I had seen scant regrowth until after my spironolactone shed but up to then, like most of the guys on here, I was using piddling amounts of estrogen. I found spironolactone to be very hard and fatiguing on the body.

I think about trying bica as much as anything to report back on it but while things are on the upswing it makes little sense to me to do it. I have been trying oral minoxidil for ten days with about ten pounds of weight gain which I hope is simply water. I am also monitoring the area under my eyes because I don't want dark circles and I might be seeing artifacts.

I am very interested in others using oral minoxidil especially liquid minoxidil. I do find the self-research of all of this fascinating sort of like Dr. Jekyll in Stevenson.

 

[JaneyElizabeth]

i switched from 4mg E to 100mg progesterone and 2mg E ten days ago

Swallowed prometrium? Most say that not enough makes it through the liver. For those who don't know about prometrium, it is sold in little spherical pills that are soft capsules. It can be fun teasing the gals who think that using it in unusual places helps grow big boobs which I do not believe at all. The little pills look like High-Ho Cherry-O pieces and will roll off the crack of the *** like a ski slope if one misses the target and then all the way across the room and under the bed where you will be on your hands and knees with one's rear in the air looking for them. MtFs will do anything for a fine set of bodacious ta-tas.

MtF sites tend to be very dour and the folks often seem to lack any sense of humor and that is not me. There is a palpable sense of dread about not doing HRT "right" in terms of "results". HRT generally if not always works fine. People just are unhappy in that it is much less pervasive in results than people realize, especially those past the age of puberty who haven't been on puberty blockers.

It seems that one should be able to use them buccally by piercing them with one's eye teeth. I tried it once and it was not tasty and I have not heard much at all about buccal use of prometrium compared to swallowing them and using them rectally.

Everyone disses on medroxyprogesterone but it is quite available after swallowing and it can also be used essentially as an AA at levels above 20 mg daily. I am taking about 10 mg daily but I forget to use it or pick up the prescription for days at a time and I don't think that provera is very important to the HRT feminization process unless used as an AA. The effects of progestins and progesterone and their importance to feminization and/or regrowth of hair is argued about frequently to no real effect in terms of the science indicating much benefit at all. Some folks claim that topical progesterone on hair, face and breasts aid in feminization but eh, I am not sure that we have good evidence hair-wise for anything, in terms of hair restoration/improvement except for the big three estrogens, although there are other varieties that are far less studied. Premarin is very interesting in this aspect and it has apparently serms within it and also more powerful horse estrogens. I certainly had good results from low amounts of Premarin in terms of body feminization but not as much facially or hair-wise.

I would like to know more about 2nd pass effects from estrogens no longer commonly used like synthetic versions which are much stronger mg for mg.

 

[JaneyElizabeth]

It could be, i never did extensive research on the adrenal glands contribution to DHT conversion so I can’t comment on it much. I know CPA+Bicalutamide counter eachother and cause problems (in my own body at least), ikarus reported the same issue. CPA+Spironolactone might behave differently since they are both steroidal, i never tried them together. If you try it look out for things like the occurrence of acne / oil production where there was none previously & let me know how it goes.

The adrenal aspect tends to be emphasize for MtFs who undergo some form of physical castration, surgical or SRS where the feeling is that testosterone can actually be too low or very low and yet there still are DHT effects if I follow the discourse properly. I don't that is the road for many MtFs in relative terms any longer because so many non-binary folks want to retain the ability to be sexual in a male context.