Exploring The Hormonal Route. Hair=life.
- Thread starter bridgeburn
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It is stronger than spironolactone and has more information on it out there compared to bicalutamide.
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I've actually had gyno three times during my more intense 'bodybuilding' days while using heavier doses. Not great at all! Knocked it into touch almost immediately though with letrozole. Im not talking abit of nipple tenderness either. The stuff is unbelievably potent and have seen guys in the bodybuilding community looking like they're developing full on boobs take it and it melts it away within a few days.
Have you used clomid as well?
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I am curious about trying out a non-agressive regime involving anti-androgens in order to go to war with hairloss and I am willing to make some sacrafices, namely loss of body hair, libido (I'd just hop on raloxifen preemtively to avoid gyno) but the problem here is that I have a low libido to begin with. Morning wood maybe 2 or 3 times a year, not jerking off for days because I simply don't feel like it, you name it.
Could you extrapolate from that that I have low T levels to begin with too? And if I did, what would anti androgens even be able to do?
Could you extrapolate from that that I have low T levels to begin with too? And if I did, what would anti androgens even be able to do?
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You won't really know until you try it as we are all different. Personally AAs make my libido rocket as my body produces more testosterone to compensate however I get bad side effects as well like brain fog & depression.
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Murkey Thumb,
Is is it possible that the way certain AAs actually work (for at least some of us) is they stop T to DHT conversion? You are essentially "Holding On" to more of your T as it's not getting converted to DHT? So instead of Normal T levels with Higher DHT levels you switch over to Higher T levels with Lower DHT levels. And More T = better Libido. I'm just trying to figure this out and understand so please correct me if I'm way off.
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I think that this explains the effect best as you can get caught in a negative loop if your original hormonal make up is susceptible
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Finasteride actually worked very well for me but eventually the sides were affecting my work too much to be tolerated.
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No, ive used Nolvadex. Also Arimidex
Have you noticed your hair loss improving in the months following taking AIs? Some have reported that in the proceeding months, there seems to be an upregulation of estrogen and therefore improved quality of hair during those times.
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Even if there is an up regulation of the estrogen receptors an AI will deplete aromatase within the follicles, making all of your androgens more dangerous to them. Normally the follicle is a source of estrogen production by local aromatization, if that gets disrupted the paracrine enviroment will shift to an androgenic paradigm. That's part of the reason why certain corticosteroids can promote regrowth; by up regulating local aromatase by several hundred percent.
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I didn't notice any change either way in all honesty.
Do you think that this would also apply to people who naturally aromatize at poor rates?
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Yes, the pattern of male pattern baldness follows a pattern of aromatase deficiency.
Perhaps finasteride non-responders aromatize insufficiently enough to benefit from the drug.
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I think aromatase is actually the main way finasteride/dutasteride work, by funneling the T to cyp19a1 enzymes instead of 5AR. Which can explain why it often doesn't help temples very much, because that area is notoriously aromatase deficient.
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Is transitioning to be MTF worth it for the hair?
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Progesterone is a false path, I can tell you that right now, in theory it inhibits DHT, but it reduces estrogen and estrogen regardless of what anyone wants to believe is the hormone that will ensure the best regrowth and maintenance of hair.
If you're male and you already have high test and low estrogen, you are going to make your hair loss worse by taking progesterone and also increase stress and anxiety because your progesterone to estrogen levels will be off.
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What a crock of sh*t, I'm dramatically lowering my DHT levels and using estriol and evening primrose oil and taking desmopressin as it increases estrogen and improves body hydration and I don't even look close to female.
If anything my skin just looks better, my girlfriend recently commented on how much nicer my skin looks and that I'm far less prone to irritation and acne. I still have big f*****g arms and a muscular chest and my face is still angular, it just now looks very hydrated and even in complexion.
You don't have to transition in order to get the effective results of estrogen, the honest truth is, most people you see who are steady into their 30s who have a full head of hair and nice skin are men with higher estrogen levels by default, that's the dirty secret most people won't tell you. Most men either have higher estrogen or they're hormonally insensitive and thus look more soft and estrogenic.
All you are doing exogenously is manually tweaking either the process of aromatase or directly adding the hormone you're missing, you're being grossly hyperbolic by saying using any estrogen at all is transitioning. Most men have no f*****g clue as to how much estrogen is in their system at any time, least of which men who have zero problems with patterned hair loss, because why would you? But I can absolutely f*****g guarantee you that it's higher in men who don't have androgen insensitivity who also have a full head of hair.
There are some freaks of nature out there who can have insane test levels and have a full head of hair, but that is not the standard. Most men who have good skin and thick hair either have comparably higher estrogen levels or are so androgen insensitive that they are functionally speaking more estrogenic.
All young teenaged and 20 something boys as the stereotype goes have "higher testosterone" but everything about their complexions is completely and utterly indicative of higher estrogen as well. You don't get soft skin and features without it. It has nothing to do with merely "being young" outside of the fact that young teenaged boys and 20 something men aromatise more test into E.
I looked extremely young for my age all of my years and over time it seems like my ability to aromatise test into estrogen has suddenly declined, for what reason I don't know, but it is now improving with certain supplements and medications, and mysteriously that really nice youthful complexion has just come roaring back and I'm 40 years old.
I still look athletic, but I do look a -lot- younger. now.
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