Exploring The Hormonal Route. Hair=life.

[bridgeburn]

Well bicalutamide doesnt touch the androgen receptor, instead bicalutamide binds to the ligand-binding pocket of the AR.

and isn't the pocket of the AR attached to the AR??

 

[I'mme]

I feel bad for him too lmao

if only he made another account...

Welcome dude

 

[HLV]

yo i was looking at my hair in the crown this morning and I almost had a heart attack, I'm a teenager and I almost have a damn birds nest in the back of my head.

3 more days until I mark 2 months on 150mg of casodex.

also im considering dropping raloxifene all together out of desperation for my hair to not get worse, although I'm not sure

look at this cool graph I found.

Welcome back DHT cel

HLV

 

[Stephen788]

How poor of me to take tamoxifen!! It raped my hair in 4 days - I know it is hardly believable. Dropping it now. Let me see what else can I do to reduce this/prevent further gyno.

Mate I had gyno pretty bad and stop spironolactone around April time and was on letro for two
Months. Although my gyno isn’t fully gone you will not notice is because it’s very thin now unless you feel it. I’m back on 150mg of spironolactone and been on that for a month now. I’m also taking 50mg of zing. People are going to say wtf haha. But right now I haven’t had any sides from taking spironolactone. My libido is still normal and I’m assuming this is because of the zinc. Ill I just want to see if I can regrow anything doing this.

 

[Stephen788]

Maybe ..or because I changed to liquid minoxidil (consumed orally) oral tablets.

Anyway, any advice on how should I tackle this gyno (only a slight lump -kinda like a small ball in 1 nipple) without harming hair?[/

Tamox and raloxifine are preventatives to getting gyno. They can only reduce the swelling and puffiness. The only way you are going to get rid of hard lumps is with letro. You probably got the gyno lump because your dosage of tamox wasn’t high enough. I’d take letro for a few weeks and when the gyno is gone resume your regime but use a higher dosage of tamox

 

[Stephen788]

I have seen a doctor, and he said, ”based on the miniaturisation of your hair you would be norwood 5-6 in the next five years”. Please believe me when I tell you I am really balding. Spironolactone had only a marginal effect on my hair.

That’s why I said see a hair specialist.

 

[Stephen788]

I have the same question, but I suspect no one in this thread has undergo gyno surgery.

I mentioned this before I am yet to see a normal sized person who has had gyno surgery that looks 100% normal. I only think it looks ok if you are muscular.

 

[keepcoolmybabies]

yo i was looking at my hair in the crown this morning and I almost had a heart attack, I'm a teenager and I almost have a damn birds nest in the back of my head.

3 more days until I mark 2 months on 150mg of casodex.

also im considering dropping raloxifene all together out of desperation for my hair to not get worse, although I'm not sure

look at this cool graph I found.

If I'm not mistaken doesn't that graph all but guarantee you'll get gyno if you drop raloxifene assuming you are on bica for upwards of a year or more?

 

[I'mme]

Mate I had gyno pretty bad and stop spironolactone around April time and was on letro for two
Months. Although my gyno isn’t fully gone you will not notice is because it’s very thin now unless you feel it. I’m back on 150mg of spironolactone and been on that for a month now. I’m also taking 50mg of zing. People are going to say wtf haha. But right now I haven’t had any sides from taking spironolactone. My libido is still normal and I’m assuming this is because of the zinc. Ill I just want to see if I can regrow anything doing this.

And letro didn't make you lose hair? How come not?

 

[I'mme]

Mate I had gyno pretty bad and stop spironolactone around April time and was on letro for two
Months. Although my gyno isn’t fully gone you will not notice is because it’s very thin now unless you feel it. I’m back on 150mg of spironolactone and been on that for a month now. I’m also taking 50mg of zing. People are going to say wtf haha. But right now I haven’t had any sides from taking spironolactone. My libido is still normal and I’m assuming this is because of the zinc. Ill I just want to see if I can regrow anything doing this.

Similar, everything is normal with me as well incl libido. Just two sides - I lost weight and got gyno in one nipple. It has been reduced a little by tamox, I think. It's just I'm afraid of its effects on hair.

 

[keepcoolmybabies]

youll get gyno as soon as you drop raloxifene is what its saying. this is the main reason I want to drop raloxifine though. (look at the image)

Figured as much. But I recall gyno being a huge concern of yours. If you drop ralox, would you just hope for the best and get surgery if gyno returns/worsens?

 

[Yar]

more hormones are formed in the adrenal glands, which are less in the testes. CPa has more effect on the eggs, not the adrenal glands. It is better to spironolactone, but not Bika, which drags testosterone up. Besides, spironolactone preserves estradiol and not how cpa destroys it, therefore on cpa increase doses of estradiol.

 

[Jerry239]

Hey
I have questions for bridgeburn
I am 21 male with Norwood 2 hairline. I have been on finasteride for 2 years but been shedding the whole time. I have been losing ground as well. And from what I read on the forums people who don't respond to finasteride, don't respond to dutasteride.
- in your opinion why don't finasteride stop or may be slow down hair loss for some people?
- what is the next drug I should take if my main goal is maintaining what I have with as minimal side effect as possible?
Thanks

 

[DinkyDino]

Something has been bugging me for a bit while reading through this thread. Why some do some go for bica and others CPA? Testosterone and DHT are the culprits from what I gather but Bica is said to increase T right? So wouldn't that mean CPA and Estrogen would be the route most would take? Or low doses of both bica and CPA? But the OP doesn't even do that and got good results.

 

[keepcoolmybabies]

Something has been bugging me for a bit while reading through this thread. Why some do some go for bica and others CPA? Testosterone and DHT are the culprits from what I gather but Bica is said to increase T right? So wouldn't that mean CPA and Estrogen would be the route most would take? Or low doses of both bica and CPA? But the OP doesn't even do that and got good results.

What @Itsnoahkennedy said. But also if you add estrogen (like you mentioned with cpa) then it will cause your T levels to significantly decrease anyway. And bica would then prevent the remaining androgens from binding. Not to mention CPA raises prolactin levels.

 

[itchymadscalp]

I got my blood test results. I changed to estradiol enanthate injection (lena kiev), did an .20ml injection a week before the test.

Total testosterone : 0.90nmol/L (7.9-35.70)

Plasmatic estradiol : 2052 pmol/L

DHT : 0.07 ng/mL (0.33-1.20)

Estrone : 559 pmol/L (55-332)

I wanted to try injection ... but it's working too well ... except it has absolutely no effect on me ................... because of androgen receptors overexpression ...

I will go back to Esstrofem 4-6mg/day ... or just like I said give up.

But if you want legit injectable estradiol you can buy from Lena ... it's legit. lena.kiev.ua

 

[keepcoolmybabies]

I got my blood test results. I changed to estradiol enanthate injection (lena kiev), did an .20ml injection a week before the test.

Total testosterone : 0.90nmol/L (7.9-35.70)

Plasmatic estradiol : 2052 pmol/L

DHT : 0.07 ng/mL (0.33-1.20)

Estrone : 559 pmol/L (55-332)

I wanted to try injection ... but it's working too well ... except it has absolutely no effect on me ................... because of androgen receptors overexpression ...

I will go back to Esstrofem 4-6mg/day ... or just like I said give up.

But if you want legit injectable estradiol you can buy from Lena ... it's legit. lena.kiev.ua

I'm curious if injections have a higher likelihood of inducing a form of telogen effluvium since they have insane spikes and then drop dramatically over the course of a week. It's like having the estradiol levels of a pregnant woman who then gives birth every week.

I know i've been shedding a lot more since switching from pills to injections.

 

[Stephen788]

And letro didn't make you lose hair? How come not?

I don’t know mate but I was off spironolactone and taking letro at 5mg for 2 months. My gyno was pretty bad though. If yours is only a pea size they you should get rid of it in a few weeks.

 

[Stephen788]

Similar, everything is normal with me as well incl libido. Just two sides - I lost weight and got gyno in one nipple. It has been reduced a little by tamox, I think. It's just I'm afraid of its effects on hair.

When I was on spironolactone first time round I lost almost a stone.
The only side I got from letro was a bit of anxiety. But if you are going on it for only a week or two you’ll be fine.

 

[John Difool]

Not to mention CPA raises prolactin levels.

Is that a good thing? What's a good level for prolactine to encourage hair growth (or at least stop it)?