Exploring The Hormonal Route. Hair=life.

Derelict

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I've tried them all with some success. Best regrowth was on spironolactone (weak AA but seems to do the job for hair) always keeping CPA at various doses then eventually Bica replacing spironolactone (lost ground because not enough E2) then increased E2 on Bica after lab work and regained ground measuring carefully free E2 T and DHT. At that point I had enough Bica to block T and enough Duta to block DHT. Switched recently to Enzalutamide oral and Darolutamide topical for 6 months as an experiment and using Eplerenone. Keeping CPA low dose till I get lab work soon. RU and Duta topical to cover any DHT left overs. Planning to make my own Duta injections with castor oil.

There was another member on this thread that said he got better results spironolactone monotherapy than bica, i think if you are using estradiol the bica might be the better choice of AA but i think while spironolactone might be weak compared to other AA's, it would work fine for the majority compared to cpa, bica etc i would never go near cpa personally, way too dangerous.
 

John Difool

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Everything is dangerous. It is just a matter on how motivated you are to do something about your appearance. @bridgeburn who was an inspiration for me to believe things were reversable, was on CPA 50mg for a while. Others who posted on this thread (@Itsnoahkennedy) used that dosage. Most transwomen in Europe get a daily 25mg. There has been research that demonstrated a low dose at 12.5mg can do most of what 25mg will do.
 
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SausageDawg

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Everything is dangerous. It is just a matter on how motivated you are to do something about your appearance. @bridgeburn who was an inspiration for me to believe things were reversable, was on CPA 50mg for a while. Others who posted on this thread (@Itsnoahkennedy) used that dosage. Most transwomen in Europe get a daily 25mg. There has been research that demonstrated a low dose at 12.5mg can do most of what 25mg will do.

(No judgement here).. does gyno concern you at all?
 

Rysteve93

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I've tried them all with some success. Best regrowth was on spironolactone (weak AA but seems to do the job for hair) always keeping CPA at various doses then eventually Bica replacing spironolactone (lost ground because not enough E2) then increased E2 on Bica after lab work and regained ground measuring carefully free E2 T and DHT. At that point I had enough Bica to block T and enough Duta to block DHT. Switched recently to Enzalutamide oral and Darolutamide topical for 6 months as an experiment and using Eplerenone. Keeping CPA low dose till I get lab work soon. RU and Duta topical to cover any DHT left overs. Planning to make my own Duta injections with castor oil.


Thanks for sharing that. Can you give me any details about your spirno experience, I’ve got it on hand and seriously considering using it.
What mg did you use?
 

Rysteve93

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What regime would you guys consider hair for life? dust.5, oral minoxidil, spironolactone 200mg topical E.

I think this is the way I will go in time. I have zero fear of side effect. I used ALOT of steroids in the past so I’m used to gyno coming and going, high sex drive - 0 sex drive.
 

Derelict

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What regime would you guys consider hair for life? dust.5, oral minoxidil, spironolactone 200mg topical E.

I think this is the way I will go in time. I have zero fear of side effect. I used ALOT of steroids in the past so I’m used to gyno coming and going, high sex drive - 0 sex drive.

I would try dutasteride, 5mg oral minoxidil and 200mg spironolactone for 12 months, if results are not what you want add 2mg E sublingually or buccaly and maybe switch the spironolactone for 50mg bica. Up to you, but i would use E as a last resort.
 

John Difool

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Thanks for sharing that. Can you give me any details about your spirno experience, I’ve got it on hand and seriously considering using it.
What mg did you use?

I was on 100mg bid. I switched to Bica after reading more about AA around same time as @Ikarus and others read @bridgeburn posts. Bica works on both adrenal and godane pathways and it's non steroidal. But Bica monotherapy defies the purpose of safety since you need to up the dosage for it to effectively block T (1mg for 4nd/dL). E2 provides a way to keep things in a reasonable range but then you are in hrt territory so don't expect no sides. It's all about compromise.
 

pegasus2

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View attachment 145358
I ❤️ My hair. All thanks to bridgburn for suggesting the hormonal route as a treatment for hair loss, it was the only treatment that provided me with any improvement after 5 years batting baldness with 30% density left while on finasteride and minoxidil.

How long did it take you to recover? I started at less than 10% density. I'm probably around 20% now.
 

Gergely

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Doing a blood test soon, any wishes?
The lis so far:
- Thyroid function
- Liver function
- Hormone Levels
 

John Difool

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Beside T & E2, E1 helps understand your ratio, Free T & Free E2 and SHBG to figure out what's left to use by follicles. DHT of course and LS & FHS if you are interested to lower T. E1S if you can to see what's your reserve. 3alpha-Androstanediol Glucuronide is my new way to snapshot DHT via adrenal pathway.
 

GRme11

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Beside T & E2, E1 helps understand your ratio, Free T & Free E2 and SHBG to figure out what's left to use by follicles. DHT of course and LS & FHS if you are interested to lower T. E1S if you can to see what's your reserve. 3alpha-Androstanediol Glucuronide is my new way to snapshot DHT via adrenal pathway.
I already checked the 3a-Diol-G for the same reason to check if there is possibility for the alternative backdoor pathway ( I also checked 17-OHP for this reason as well) . 3a-Diol-G, came below the normal ranges. If anyone needs more information about blood tests , check my thread here : https://www.gourmetstylewellness.com/intera...-hormones-kinda-messed-up-need-advice.128404/

I already did plenty, and I hope I can help you with some results of the blood tests. Thank you
 
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GRme11

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How are you able to order these tests,? Are you in the US?
Nope. I am just ordering them to the lab, but they can be quite pricey sometimes because they are private. If a doctor prescribed them to me, it would not have been so costly for sure, but it's pretty hard to get these tests prescribed by a doctor, that's why I am ordering them private. Thanks.
 
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Rysteve93

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I’m starting spironolactone this week. I will ease up to 200mg over the space of a month or two. I loose next to no hair at all each day, even after shower and rubbing my head (thanks to oral minoxidil)

For the guys on this forum that have experience with spirno, should I expect a shed due to the hormonal change?

ive also been using estrogen cream most nights with weekends off to see if this will help boost my hairline
 

John Difool

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What Estrogen cream? The OTC one from retailers like Amazon requires you to put the whole container each day to get decent levels. Go back 500 pages earlier to read about Estrogel . Due to relatively low half life stopping on weekends is a bad idea. It's not like DHT is taking a break Saturdays and Sundays.
 
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