Exploring The Hormonal Route. Hair=life.

John Difool

Senior Member
My Regimen
Reaction score
1,336
3 to 6 months to stop hairloss.by lowering T depending how you respond to it you are essentially getting chemically castrated. You still need E to balance your hormones and regrow. You won't regrow hair on CPA only. You also need Duta to nuke DHT meanwhile till your T is low enough to stop producing DHT or if your T is generated by the gonadal gland called backdoor pathway.the reason folks with an orchiectomy still generate T. Note that a better way to take care of that remaining T is to use Bicalutamide. Again getting castrated physically or chemically is not always getting you off the hook on drugs for hair loss. So if you start with CPA you should consider Bica longer term. CPA is not a mild drug. If you do it for hair, you should consider Spironolactone instead. It's a weaker AA bur it is also a stronger MR antagonist which is good for.hair. All these info about anti-androgens is available on Wikipedia. Monotherapy on each of those require high dosage and with this comes even more side effects. You lose man capacity and gain female appearance to some degree. For transitioning it's great but not if you are looking to do it just for hair. You can't have it both ways (yet).
 

John Difool

Senior Member
My Regimen
Reaction score
1,336
I'm just following the general guidelines prescribed for transgender people. It's not exactly the safest thing to do without professional supervision.
I can get cancer, blood clot, liver/kidney failure.

Where do you get your legalon from?
 

Derelict

Senior Member
My Regimen
Reaction score
1,308
Where do you get your legalon from?

Sorry for jumping in, but do you know of any ways to increase aromatase without estradiol? i fucked my hair up badly with letrozole, i stopped it in march but my hair has still hardly recovered. Any help would be appreciated.
 

Father_of_Shiseido

Experienced Member
My Regimen
Reaction score
339
3 to 6 months to stop hair loss.by lowering T depending how you respond to it you are essentially getting chemically castrated. You still need E to balance your hormones and regrow. You won't regrow hair on CPA only. You also need Duta to nuke DHT meanwhile till your T is low enough to stop producing DHT or if your T is generated by the gonadal gland called backdoor pathway.the reason folks with an orchiectomy still generate T. Note that a better way to take care of that remaining T is to use Bicalutamide. Again getting castrated physically or chemically is not always getting you off the hook on drugs for hair loss. So if you start with CPA you should consider Bica longer term. CPA is not a mild drug. If you do it for hair, you should consider Spironolactone instead. It's a weaker AA bur it is also a stronger MR antagonist which is good for.hair. All these info about anti-androgens is available on Wikipedia. Monotherapy on each of those require high dosage and with this comes even more side effects. You lose man capacity and gain female appearance to some degree. For transitioning it's great but not if you are looking to do it just for hair. You can't have it both ways (yet).
Resorting to full MTF HRT just for the sake of hair is mental illness. We have the option of hair system.
 

ali.talebi1994

Member
My Regimen
Reaction score
18
Resorting to full MTF HRT just for the sake of hair is mental illness. We have the option of hair system.
you're right but without hair i'm falling into depression and finasteride alone doesn't work, I have been on finasteride 2mg/d for 6 months :confused:
recently i have added CPA 12.5mg/d to my regimen (it has been 47 days by now)...
it won't cause feminisation without estradiol and i hope it will help my hair a lot :rolleyes:
 

pegasus2

Senior Member
My Regimen
Reaction score
4,513
you're right but without hair i'm falling into depression and finasteride alone doesn't work, I have been on finasteride 2mg/d for 6 months :confused:
recently i have added CPA 12.5mg/d to my regimen (it has been 47 days by now)...
it won't cause feminisation without estradiol and i hope it will help my hair a lot :rolleyes:

The risk of gyno from CPA monotherapy is up to 30%. That's probably not much different than estradiol monotherapy, but less effective at promoting hair growth.
 

Father_of_Shiseido

Experienced Member
My Regimen
Reaction score
339
you're right but without hair i'm falling into depression and finasteride alone doesn't work, I have been on finasteride 2mg/d for 6 months :confused:
recently i have added CPA 12.5mg/d to my regimen (it has been 47 days by now)...
it won't cause feminisation without estradiol and i hope it will help my hair a lot :rolleyes:
If cypro reduces your LH and FSH level, then you will Experience testicular atrophy. You can use 200 mg spironolactone or 25 mg bica ED, which have fewer side effects than cypro.
 

John Difool

Senior Member
My Regimen
Reaction score
1,336
CPA is the bomb and if I were to do it for hair I would jump to spironolactone. Bica works better with E2 and even if spironolactone is a weaker AA it has more proven benefits.
 

Gergely

Experienced Member
My Regimen
Reaction score
531
Well my E2 is down and my total T is doubled from the previous test.(worth noting that i only took the pills after the blood sampling 24 hours apart) I'll post the results when i have all of them.
 

ali.talebi1994

Member
My Regimen
Reaction score
18
If cypro reduces your LH and FSH level, then you will Experience testicular atrophy. You can use 200 mg spironolactone or 25 mg bica ED, which have fewer side effects than cypro.
yeah I have recently started to feel some pain in my testicleso_O
last year I tried 200 mg spironolactone for about 2 months and I had no ball ache but my liver could not tolerate and I got skin rashes and hives:confused:
my liver enzymes had raised to 4x of the normal rangeo_O
but now I am fine on CPA 12.5mg/d and I will have a blood test in this Monday, it will contain a full check up plus T and prolactin... any thing else i should add to check???
 

Father_of_Shiseido

Experienced Member
My Regimen
Reaction score
339
yeah I have recently started to feel some pain in my testicleso_O
last year I tried 200 mg spironolactone for about 2 months and I had no ball ache but my liver could not tolerate and I got skin rashes and hives:confused:
my liver enzymes had raised to 4x of the normal rangeo_O
but now I am fine on CPA 12.5mg/d and I will have a blood test in this Monday, it will contain a full check up plus T and prolactin... any thing else i should add to check???
I don't know. But bica is a better option than CPA. Testicular atrophy in not fully reversible.
 

Gergely

Experienced Member
My Regimen
Reaction score
531
SHBG is not there, because they forgot about it... Everything else seems to be in order
Edit: SHBG : 48,84 nmol/L better late than never
2020-09-15
233.png
2019-12-04
55.jpg
Any input would be appreciated, since i have no idea what i'm looking at.
 
Last edited:

Derelict

Senior Member
My Regimen
Reaction score
1,308
Are you taking bic? I recall you mentioning the swap from spironolactone > bic.

Myself I have just started spirno

Bica is probably better if you take estradiol, but monotherapy wise spironolactone is probably better than bica. Some guy in this thread said he tried both and found spironolactone to be superior than bica for his hair.
 

Rysteve93

Established Member
My Regimen
Reaction score
121
Bica is probably better if you take estradiol, but monotherapy wise spironolactone is probably better than bica. Some guy in this thread said he tried both and found spironolactone to be superior than bica for his hair.

really hoping spironolactone can give me the boost to my hairline! How’s your recovery going from letro?

also I seen you have mentioned thinking about the use of estrogen, what’s your thoughts now?

I rub small dose of bio - estrogen to legs and body, of course hairline every night. Thinking of using the Estrogel 0.06% Estradiol
 

Derelict

Senior Member
My Regimen
Reaction score
1,308
really hoping spironolactone can give me the boost to my hairline! How’s your recovery going from letro?

also I seen you have mentioned thinking about the use of estrogen, what’s your thoughts now?

I rub small dose of bio - estrogen to legs and body, of course hairline every night. Thinking of using the Estrogel 0.06% Estradiol

Im giving it until end of this year beginning of next as to whether i pull the trigger on estradiol, my recovery isn't going so well tbh. I just bought some castor oil and NAC hoping it might help a little. I don't have that much hope in it helping significantly but even a little improvement would help. I am extremely reluctant to start it though, it is an absolute massive last resort, one i hopefully won't need.
 

Gergely

Experienced Member
My Regimen
Reaction score
531
Would the imbalance between Estrone and Estradiol be solved by adding progesterone? Or am i stupid and that's unrelated
 

Rysteve93

Established Member
My Regimen
Reaction score
121
@John Difool can you please elaborate on your spironolactone experience, you mentioned several pages back your experienced good results. What dosage did you use? Did you taper up? Onset time for visual results? Currently week two, first week 50mg daily split 25mg. This week 100mg daily 50mg split. I’m pissing a lot so I know it’s doing what it was designed to do.
 
Top