Exploring The Hormonal Route. Hair=life.

JaneyElizabeth

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No, you are absolutely right. I was doing Rob's massages and doing derma-rolling and taking spironolactone and that is a lot to have going on and it was a miserable summer and I was way too sure that a shed wouldn't happen to me. I was actually about to try a wire brush and then it was like, well, boar's hair seems to be yanking it all out anyway.

I thought though that the spironolactone would protect me and it did the opposite perhaps but this is all anecdotal and spironolactone is cheap and works for many folks. I stayed on it a year and for once, I should have probably dumped it when I started having all of the sides last summer but see, I don't believe in sides.... Live and learn. I remember though that the hair seemed like it wanted out/off. I think that it itched and I couldn't keep my hands out of it. It really probably was a "benevolent shed" which term I have trademarked but I must have hope for the future since I have pictures up on my site of the bald head and I wouldn't be able to do that otherwise. I was really proud of myself:

I put up some representative pics and one entitled "shed of dubious cause".
 

John Difool

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I didn't get baseline numbers so it won't be very interesting. All I'm concerned with is if I see breast development.

Interesting fact, Asians get their different skin color from their Eastern diet. It has nothing to do with having different genes. Also, blue eyes are caused by diets high in animal fats and dairy. All humans actually have the same genes, and our differences all come down to our lifestyle choices.
Is having bad genes a myth?
 

Derelict

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Which one? valerate, acetate, conjugated?

At any rate, oral is not the preferred route.

Do you get your estriol from alibaba? i guess i will give my current regimen another few months before i try it, i know you and pegasus are using estriol topical but im trying to avoid topicals as much as possible tbh.
 

franzliszt

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@John Difool

Hi, Ive just read your post on the previous page regarding the DHT back door pathway and the use of Abiraterone Acetate - where one source this at a reasonable price?

I've found it on the website below - but it's literally the same price as a hair transplant in Turkey.


Are there any other drugs that can stop this back door action?
Heres a link to abiraterone acetate powder, I'm not sure if it's suitable to be used as a topical, or if it's safe to make your own tablets out of it (especially ordering from china). I'm currently researching ways into stopping that DHT backdoor pathway too. More plates more dates did a good video on it. There are some other compounds used for castration resistant prostate cancer that are suitable for our purposes, Darolutamide being the best there is (although extremely expensive). Apalutamide and enzalutamide are slightly cheaper, all of which can be found on Alibaba. I'm curious if you could make your own pills by using gelatin capsules, or if the filler material is required for it to work properly. Safety is a concern too, and I'm not sure how expensive it would be to get the compound tested for purity, heavy metals etc. Abiraterone Acetate is comparitively inexpensive, but I'm not sure how effective a topical would be. I hope this is helpful, let me know what you decide to do, and what infomation you find out
 

JaneyElizabeth

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What would be a good oral dosage of estriol to start at?
I guess you are asking Pegasus. I think that estriol might work but the idea would be that estriol is less feminizing than estradiol, otherwise why not use estradiol? It is much easier to get.
 

mushroom

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Have you done any blood work?
Yeah, free T like 10pg/ml, Estradiol 92pg/ml. Ultrasound of testicles is okay. My last guess is adrenal tumor or adrenal hyperplasia, so I will check it soon. If not I’m going to cry 24/7. Or maybe cyproteron doesn’t work for me, but it’s strange. I’m thinking about orchiectomy. Is it possible to have testosterone in the male range after an orchiectomy?
 

JaneyElizabeth

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Yeah, free T like 10pg/ml, Estradiol 92pg/ml. Ultrasound of testicles is okay. My last guess is adrenal tumor or adrenal hyperplasia, so I will check it soon. If not I’m going to cry 24/7. Or maybe cyproteron doesn’t work for me, but it’s strange. I’m thinking about orchiectomy. Is it possible to have testosterone in the male range after an orchiectomy?
No.
 

John Difool

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At 50mg you are using 2-4x what you should be even as a transwoman. Bica 50mg would probably work better. High dose of CPA beside liver damage will raise prolactin which sucks for hair. Your free T is quite high ,and E low range so raising E2 would help if you are on hrt. Check your SHBG to keep it in range. If you want to know your adrenal activity then check DHEA.
 

JaneyElizabeth

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Estrogel: Should you be using it? And if you aren't, then why not?

@bridgeburn used estrogel daily:

"At that point my results were not yet cosmetically significant.. could be a coincidence but it did seem that right after I switched to using estrogel everyday, results jumped up and when i made more extreme switches later results jumped up again"
at page one, instant thread.

I all but swim in it. He continues here:

HillTopLumber said:


Wow man youre an inspiration, what do you think was the main medication that helped increase your density so much, the antiandrogens or the Estradiol?
Im not even taking an anti androgen for more than 2 months and still gaining. I think estrogen is more in important long term but maybe the minoxidil can give more immediate results. and its really the combination which is great. but i have seen some amazing regrowth using antiandrogen approach without minoxidil so i know it is possible, but some probably need the extra boost of minoxidil.
minoxidil will lose effectiveness without changing hormones and your hair eventually matches your hormone profile. it didnt stop my chest hair from falling out although it temporary grew them faster before they thinned. but i think minoxidil will keep continuing to work as long as there are no male hormones to antagonize it.

For any trans folks, I use it as a hair dressing essentially when I don't have to go out and perhaps together with the oral minoxidil which I have taken for three weeks now, I seem to be experiencing explosive hair growth. It's always easy to over-estimate with different lighting and such but I feel that I am pretty close to my mid-20's hairline or younger. I have never been one to shy away from mirrors but always there was that incipient bald spot and it has filled in almost completely. The hair has gotten long enough for bangs and I just push them insouciantly to either side and basically the hair styles itself and I don't have to do anything but brush it forward. Paul's is a little longer in the back and a little punkier somehow. The Beatles raised me and it has always hurt not to have hair as good as my fathers.

I continue with the 2.0 mm micro-needling and I find it much less taxing than the shorter mm ones; I think that I could easily do it twice a week. For anyone who has transplants or might be intending to, this might be the answer to the scarring issues or for units that don't take. I am not up to date on transplants but strangely enough, if I understand correctly, the techniques from 20 years ago could be superior in terms of follicle cross-talk, which is related to the mouse hair-plucking studies.

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JaneyElizabeth

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I am trying to keep up a bit with the founder's dosing. He was taking his estrogen sublingually so that means more or less it is three times as potent but has a shorter half-life from what I have read. This is about at his 9 month mark, I think:
abcnamed said:


hi, may l ask you, what's your final complete regime now?
which kind of estradiol are you using?
ethinyl estradiol ،valerate?! topical or orally or both? in which dose?,
and are you using cyproterone 50 now?
thanks
.5mg Dutasteride
2.25mg oestrogel topically
2mg estradiol hemihydrate, buccally
50mg cyproterone
10mg oral minoxidil, every other day

In terms of strength, this would be a pretty standard male to female HRT protocol for someone well into transition or maintaining adult female target levels except the CPA is off the charts. This is puzzling because he was doing fine without CPA but he might be struggling with the temples. He cut back on the oral minoxidil because someone alleged that that was causing some/much of his growth. I highly doubt this because the growth he has simply doesn't resemble minoxidil hair growth in its pervasiveness. I don't think anyone is claiming that oral minoxidil on its own could do anything close to his gains. He mentions that oral minoxidil has a short half-life so I am not sure why he didn't just go to 2.5mg twice a day.

He explains that he decreased oral minoxidil dosage due to excessive unwanted hair growth.

On August 25th, 2018, this was his regimen:

1mg dutasteride everyday, 6mg buccal estrofem (a couple times i took 8mg but mostly 6mg a day), 200mg spironolactone, 500mg sulfasalizine, 10mg oral minoxidil every other day and topical minoxidil every other day on alternating days (I don't really measure just cover the area). He also was taking 100 mg of progesterone orally which is a marginal dose. October 2nd, he added one Diane pill per week.

All he really needs in my estimation at this point is the 6mg to 8mg estrofem. The oral minoxidil might be important also but that isn't a hormonal med. He shouldn't need oral minoxidil and sulfasalizine, just one or the other from what I have read as long as a person is using topical minoxidil with the sulfasalizine. I think by this point the spironolactone is largely useless as is the dutatsteride but he doesn't know this because he doesn't test so he can't be sure he is hitting targets, perhaps, without an AA.
 
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