- Reaction score
- 80
I started estrogel a few days ago. I’m not planning to take enough to significantly down-regulate my testosterone, but I hope that it will reduce it to within normal male ranges again since bicalutamide raises your testosterone. Even that’s doubtful at my dosage though. The primary reason I chose to apply estrogel topically to my scalp is because estrogen CAN have a more targeted local effects, some of it will certainly go systemic, but I’m hoping to form a gradient of sorts with the highest concentration at the site of application. Studies show that estrogen can pretty substantially downregulate AR expression as well as being a growth agonist itself. So I’m hoping it provides that trifecta of results for me, slightly less testosterone, less AR expression, and regrowth. Curing my Seborrheic dermatitis which has been unresponsive to anything else would be a nice cherry on top.