Exploring The Hormonal Route. Hair=life.

[NickGardner0651]

Perhaps Bicalutamide 50mg + finasteride is the golden mean? I am thinking about removing the gyno with an operation
Finasteride and dutasteride sooner or later stop helping everyone. So we all need a fallback. I began to go bald at the age of 16, with aggressive baldness, dutasteride and finasteride are powerless

I have heard good things about Bicalutamide as being a solid AA (similar to spironolactone). Finasteride should be a standard in any regimen as it is best used for halting any further loss (The earlier you get on it the better). Through my own analysis the only thing that is going to promote substantial re-growth is estrogen.

 

[Almas]

I have heard good things about Bicalutamide as being a solid AA (similar to spironolactone). Finasteride should be a standard in any regimen as it is best used for halting any further loss (The earlier you get on it the better). Through my own analysis the only thing that is going to promote substantial re-growth is estrogen.

Now I am Norwood 1, but I see myself rapidly retreating despite taking Dutasteride. Since Bicalutamide will only preserve my hair, I should probably jump on it as soon as possible. I can do this in the fall when I move to a country where you can buy it. I see no other way out. There is minoxidil, but it works for 1-2 years due to the sensitivity of the receptors. Use minoxidil - how to pour water into a cup with a hole in the bottom
I am only afraid of the effects of Bicalutamide. Research shows that it increases the risk of heart failure. Also we have no information about long-term safety, to be honest, I'm scared. But I'm ready for a lot for the hair

 

[Screeech]

Hello,
the reccomended oral dose of nubeqa (darolutamide) is 600 mg a day. This is an oral dose, not a topical one.

Yeah, I was aware of that, that was for the treatment of prostate cancer too, not hair loss.

I have been using a .05% amount every day dissolved in ethanol and PG and it stopped my scalp itch and stopped me from waking up with morning wood for the first time in my life, which would suggest it's very much efficacious at that amount.

Only problem is it doesn't work for me, but nothing has, as my hair loss is not predominantly androgen related I suspect.

So I would reccommend you trying it at a dose like that if you're interested because I think it works at that strength and it is obviouly cheap as a result.

Those three drugs you mentioned all failed me as well (RU actually worsened my situ). @Norwoody mentioned the ONLY things that have been efficacious for me: oral min and estradiol. I'm on the fence about whether needling has every helped me but others swear by it.

Have you tried PGE2?

That seems to be another potentially successful growing agent, albeit an expensive one.

 

[Obsessive]

Yeah, I was aware of that, that was for the treatment of prostate cancer too, not hair loss.

I have been using a .05% amount every day dissolved in ethanol and PG and it stopped my scalp itch and stopped me from waking up with morning wood for the first time in my life, which would suggest it's very much efficacious at that amount.

Only problem is it doesn't work for me, but nothing has, as my hair loss is not predominantly androgen related I suspect.

So I would reccommend you trying it at a dose like that if you're interested because I think it works at that strength and it is obviouly cheap as a result.

Have you tried PGE2?

That seems to be another potentially successful growing agent, albeit an expensive one.

I have PGE2 but have not added it yet since I can hardly tolerate the skin effects of oral min (only using 1.25 mg a day!!) and additional PGE2 side effects would be hard to tolerate. I'll definitely have to drop oral min at some point but trying to get things in decent shape for a procedure.

 

[DogoDiLaurentiis]

For those over 44 years, metformin might be ineffective.
pubmed.ncbi.nlm.nih.gov/19878986
ncbi.nlm.nih.gov/pubmed/28770322
www.ncbi.nlm.nih.gov/pubmed/31794067

I'm not sure where you're seeing an age constraint specifically, and I'm exceptionally sensitive to medications, a doctor told me that there was a 10 year limit on using ketoconazole before it stopped working for seborrhea and I still use it.

 

[Yar]

Используйте эстрадиол для восстановления роста волос на голове, также помогает спиронолактон, не нужно мазать эстрадиол на кожу головы, нужно наносить его на кожу плеч или предплечий. Я за все время борьбы за волосы пришел к вывод, что эстрадиол идеальное средство для волос на голове, он сушит волосы, жирные от андрогенов, эстрогены наоборот сушат волосы, они становятся от него рыхлыми, жирные волосы наоборот вредят!

 

[Yar]

Estradiol only estradiol

 

[Screeech]

I have PGE2 but have not added it yet since I can hardly tolerate the skin effects of oral min (only using 1.25 mg a day!!) and additional PGE2 side effects would be hard to tolerate. I'll definitely have to drop oral min at some point but trying to get things in decent shape for a procedure.

What are the side effects of PGE2?

Hadn't heard of anything significant previously, although there's not much info on it in saying that.

How did you go about getting PGE2 into your country?

I have been told that it needs to be sent expressly, and in my country stuff that is sent express from another country - especially China - AND that is in a vial, is a surefire guarantee for inspection by customs, which has resulted in me losing it previously.

 

[Almas]

3 or 3.5

Hello, I want to use Bicalutamide with Finasteride like you. Are you sure 50mg is the optimal dose? What do you think of 25mg? This is not enough?
You rarely visit the site, you can answer me whenever you want. When you answer me, I will receive a notification by mail. You leave valuable information on the forum
At 25mg, the risk of gynecomastia is much lower and is a tempting choice. Maybe you should use 50mg, and for gynecomastia, temporarily use 25, and then use 50 again when it disappears?
In general, I need your comment. Share tips. What can I expect besides gyno? I want to delete it with an operation. How has your body changed, etc.? Tell us what I should be ready for. And in the long run, too. For example, I've heard that it increases the risk of heart failure.

Excuse me for bad english

 

[Jonny Craig]

needling is the king

i didnt start growing in raw grass fed patches in scalp until i combined bi-estro, ketoconazole cream with derm pen microneedling at 2.5mm

oh ya? bi-estro cream worked good for you?

which dosage, frequency and where do you apply?

 

[Jonny Craig]

y'all getting results on bi-estro cream? anyone? I dosed tonight, and considering ordering more but wondering if others got results with it????

I've used it over a year ago, I think with decent results (also sides were starting to creep in, very itchy nipples, but dick was OK, although balls getting small) the thing is my hair was so good over a year ago I didn't really realize results were good until I look back at pics.

P.S I just got an online script for oral dutasteride today, paid $$ for it but don't think I'll take it. So many stories of it hurting hair, just endless sheds, weighing that VS all the sides including potential permanent ones... I feel like it's a better gamble to just go all in with estrogen, no? at least it's not as unpredictable, and tbh I feel pretty good on estrogen, and it's good for skin, at the very least, should not give brain fog.

 

[deathdiss]

oh ya? bi-estro cream worked good for you?

which dosage, frequency and where do you apply?

Bi-estro cream works good in conjunction with ketoconazole.


1 or 2 pumps a day all over scalp.

I feel like it won't work that great on it's own.


You get minimalistic gains if your diet is garbage.

 

[Jonny Craig]

Bi-estro cream works good in conjunction with ketoconazole.


1 or 2 pumps a day all over scalp.

I feel like it won't work that great on it's own.


You get minimalistic gains if your diet is garbage.

fair. which ketoconzaole? like a cream, or nizoral?

btw when I used bi-estrocare a year ago, and did 2 pumps a day, my skin also looked terrific.

curious to hear others reports though too...

 

[deathdiss]

fair. which ketoconzaole? like a cream, or nizoral?

btw when I used bi-estrocare a year ago, and did 2 pumps a day, my skin also looked terrific.

curious to hear others reports though too...

oh man i could go on about how I use it on my face it's INSANEEEEEEEE. I look at photos of when i was 21 and now im almost 27 and I don't look like I've aged a single bit.

It's also proven in studies that it increases collagan production...although those studies are only done on women.

So if you microneedline face with bi-estro= YOUTH

of course diet as well

And regaring ketoconazole I favor the cream over the nizoral. I hate nizoral and don't trust it.

See if you can get it through pharmacy.

 

[Jonny Craig]

oh man i could go on about how I use it on my face it's INSANEEEEEEEE. I look at photos of when i was 21 and now im almost 27 and I don't look like I've aged a single bit.

It's also proven in studies that it increases collagan production...although those studies are only done on women.

So if you microneedline face with bi-estro= YOUTH

of course diet as well

And regaring ketoconazole I favor the cream over the nizoral. I hate nizoral and don't trust it.

See if you can get it through pharmacy.

true.

alright I just ordered 2 bottles of bi-estrocare, gonna give it another go and i'll be consistent this time.

I did get a script for oral Dutasteride this morning, but I don't think I'm gonna go through with it.

 

[deathdiss]

true.

alright I just ordered 2 bottles of bi-estrocare, gonna give it another go and i'll be consistent this time.

I did get a script for oral Dutasteride this morning, but I don't think I'm gonna go through with it.

i don't know much about the other stuff. I went a different route for my hair growth.

im more interested in keeping my hair gains rather than relying on pharmacy drugs for life


All I heard is that duta is more effective than finasteride

 

[Norwoody]

oh man i could go on about how I use it on my face it's INSANEEEEEEEE. I look at photos of when i was 21 and now im almost 27 and I don't look like I've aged a single bit.

It's also proven in studies that it increases collagan production...although those studies are only done on women.

So if you microneedline face with bi-estro= YOUTH

of course diet as well

And regaring ketoconazole I favor the cream over the nizoral. I hate nizoral and don't trust it.

See if you can get it through pharmacy.

How long have you been on bi-estro? What's your needling regimen?

Yeah it seems my skin has improved from it too after just a few weeks. Counteracts minoxidil nicely.

Nizoral helps but it is very weak, it only gets rid of the itch for sometimes only a few hours for me. I need to figure out how to get rid of the excess sebum.

 

[deathdiss]

How long have you been on bi-estro? What's your needling regimen?

Yeah it seems my skin has improved from it too after just a few weeks. Counteracts minoxidil nicely.

Nizoral helps but it is very weak, it only gets rid of the itch for sometimes only a few hours for me. I need to figure out how to get rid of the excess sebum.

hmmm i would say since i begun the regime so about 4 1/4th months so far.


i was doing 1.5mm needling every single week then switched to 1.7mm needling and now I only do 2.5m Needling aggressively at speed 5-6 on the dr pen


yeah with nizoral i dont trust it. i think it was something that made me diffuse everywhere. i did read that that's one of the side effects of nizoral shampoo but only a small minority have that effect.



slapping on bi estro cream with needling really nice. u only need a small finger for the whole face. Makes it smooth all over...really insane how it works.

Estrogen and skin. An overview - PubMed

As the population of postmenopausal women increases, interest in the effects of estrogen grows. The influence of estrogen on several body systems has been well-documented; however, one area that has not been explored is the effects of estrogen on skin. Estrogen appears to aid in the prevention...

pubmed.ncbi.nlm.nih.gov

 

[deathdiss]

i didnt start at 2.5mm because it was too painful. even at 1.00mm needling i found it painful so i worked my way up with pain tolerance

 

[JaneyElizabeth]

Is transitioning to be MTF worth it for the hair?

It can be. Like everything, such conclusions are subjective but I would say that you would need an inclination to be at least androgynous or non-binary for it to be worth it for the hair but older guys no longer breeding might value hair either more or less in such a context. Younger guys can bank sperm if they want. Generally if you look at materials on what makes people in general attractive, and then what makes males attractive, as was said above, it is having an oval-ish face with big eyes and features that have not spread very far apart. Being average in all aspects strangely enough seems to be more attractive than being "perfect" so that's one reason why baldness is so crippling looks-wise and then when you add in all of the other deleterious life effects of testosterone, it could be argued that as little exposure to adult levels of T are best for folks who don't depend upon their bodies for physical labor.

If you want to discuss this more fully, we have several XY's with various motivations here: https://www.gourmetstylewellness.com/intera...al-posts-prove-it.130425/page-15#post-1932651

I used to post more so here but this is a success thread and it probably doesn't need to grow anymore because it is already like a novel to read but also very interesting and sort of a page-turner as you follow @bridgeburn through his travails. Did he succeed? Definitely but he was completely feminized so cis-guys couldn't really emulate him unless they got breast reductions which people expected him to do but, and I understand why, he liked his boobs and then said that since he had hair now and a life, that he was outy or whatever which was a classic send-off that he violated less and less. He last was on here even lurking in January of last year, I think.