- Reaction score
- 2,035
Do AA's down-regulate the E2 receptors? If not then that might be a reason for AA therapy. I mean, I think "down-regulation" is usually an excuse as to why people don't want to use finasteride or I guess HRT. It doesn't seem to be a factor in Bridge's hair miracle and he was pushing very high E2 levels. Plus, again, like I frequently say about Premarin and ethinyl estradiol, we don't have to use them for life or maintain extremely high E2 levels for life, only until hair is restore and then titrating down to the axis-maintaining levels should maintain hair. I think an extended period of elevated E2 periods and as we saw with Bridge and my time period is similar, two years is probably what it takes at least. This July will be when I had my spironolactone shed which ended in September maybe so I am at 18 months or so in terms of recovery and six more months ought to do it. The hair also has to change in texture as it loses any "mullet" elements and I am really seeing this currently. Also, HRT was already working but adding oral minoxidil seemed to really accelerate things, if not kick-start them. You might add oral min to help get things off the ground so that HRT can finish healing the follicles and restoring your hair.There is the hair system route, it's not ideal but if nothing else works...
Being on higher levels for a long period may downregulate the E2 receptors, which is why estrogen implants aren't geat. They produce a steady level of estrogen, which is unnatural. The same may be said for being on consistently high levels, from injections and waiting for the end of the half life from estradiol valerate before injecting may be better.
If this is doable, then why would it only work for some? Hair genes? Maybe. My parents both have great hair in their 80's so maybe my hair loss was due to just some marginal factors that HRT had to correct.