Exploring The Hormonal Route. Hair=life.

Adri23

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Mb you're right, i heard that its pretty common fully dissolved in Polyethylene Glycol tho with some addes stabilizer, mb old info tho.
It can dissolve in Polyethylene Glycol as well, but I have mct oil c8 + ethanol 95% which dissolves dutasteride pretty good as well, so one for the solubility and the other for the absorption. The amount of alcohol on my solution is 0.226 ml if I take 1.7 ml of my 5 mg/ml solution. 0.226 ml of alcohol to put things in context is like what would contain a ripe banana or 100-150 ml kefir.
 

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BeardCombover

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Used to have lot of inflammation too, in fact I have some in some small areas but not as bad as before. I cycle clobetasol propinoate, like a full week then 2-3 week rest and a maintenance of 3 times per week for a week and if there is no aches or redness I stop if for some time. It has been going good. However I dont know how much it is helping since I used clobetasol before and didnt have this healthy scalp. I think supplementing with many antioxidants and anti inflammatory stuff are helping more because it is the only thing I've changed from last year to now
I tried clobetasol once and it instantly killed my hair for some reason. =(
Fully agree that antioxidants and anti inflammatory are must, testing oridonin, isoliquiritigenin and wogonin atm.
 

Adri23

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I tried clobetasol once and it instantly killed my hair for some reason. =(
Fully agree that antioxidants and anti inflammatory are must, testing oridonin, isoliquiritigenin and wogonin atm.

Damn thats not great. Clobetasol give me sh*t texture too.

Im using Glynac, vitamin C, astaxanthin, Vitamin E, Vitamin D3 and K2, melatonin 4 mg, magnesium, zinc, copper and omega 3 DHA and EPA at the moment.

The melatonin also contain some vitamin B1, B12, B6 and 5-HTP
 

BeardCombover

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Damn thats not great. Clobetasol give me sh*t texture too.

Im using Glynac, vitamin C, astaxanthin, Vitamin E, Vitamin D3 and K2, melatonin 4 mg, magnesium, zinc, copper and omega 3 DHA and EPA at the moment.

The melatonin also contain some vitamin B1, B12, B6 and 5-HTP
Not bad! Aside from oridonin, isoliquiritigenin and wogonin, i use only ascorbic acid, D3+K2, Zinc, q10, curcumin and B complex.
Melatonin is great, agreed.
 

Adri23

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Not bad! Aside from oridonin, isoliquiritigenin and wogonin, i use only ascorbic acid, D3+K2, Zinc, q10, curcumin and B complex.
Melatonin is great, agreed.
Those are some great ones. I forgot I also drink matcha Tea sometimes and used to take turmeric with black peppermint, but not taking it rn (tho I want to start it again)
 

Adri23

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My hairs are kinda fucked btw. =(
Apart from crown kinda okish.
View attachment 190016
But crown seems pretty fked. =(
View attachment 190017
It is kinda bad, it reminds me of my scalp before the supplements, my crown was very similar if not the same as yours. For some reason supplements did the trick for me. I guess cycling clobetasol does something too, but idk how much since with clobetasol alone my crown was still red af.

Have you tried different topical corticosteroids? Maybe those do not kill your hair, clobetasol is a very potent one.
 

BeardCombover

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It is kinda bad, it reminds me of my scalp before the supplements, my crown was very similar if not the same as yours. For some reason supplements did the trick for me. I guess cycling clobetasol does something too, but idk how much since with clobetasol alone my crown was still red af.

Have you tried different topical ? Maybe those do not kill your hair, clobetasol is a very potent one.
Other topical corticosteroids nope, but it was much better when is was on bica 50mg and 2 tablets of dissolved ketoconazole on scalp.
I dont feel any inflammation tho, and it seems that hair doesn't fall out since i started to take aspirin. For now at least.
 

Adri23

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Do you have oily scalp? If you do maybe it is Seb derm and the bic was reducing your sebum and ketoconazole was killing the Malassezia
 

BeardCombover

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Do you have oily scalp? If you do maybe it is Seb derm and the bic was reducing your sebum and ketoconazole was killing the Malassezia
My trichologist said i don't, but i often had seasonal escalation of sebum and inflammation, so I suspect having it in the end.
Well, after seeing these photos, ill try do smth with it for sure. Think ill start with Nizoral every day.
 
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Adri23

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My trichologist said i don't, but i often had seasonal escalation of sebum and inflammation, so I suspect having it in the end.
Trichologist are useless most of the time. I bet we know more than them lol. You prob have it. Like it is a very frequent skin pathology, so if it improved with ketoconazole + bica I would say it was likely that(maybe some reduction of local androgens with the bica was helping with the inflammation as well)
 

BeardCombover

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Trichologist are useless most of the time. I bet we know more than them lol. You prob have it. Like it is a very frequent skin pathology, so if it improved with ketoconazole + bica I would say it was likely that(maybe some reduction of local androgens with the bica was helping with the inflammation as well)
Ye, agreed. Just made an appointment with another one via app. We'll see what he say.
Video where the crown start. Scary. =(
https://vimeo.com/1076849039/c12a1656b0?activityReferer=1
 
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Adri23

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Ukraine

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Интересно, почему никто не использует E4 (Estetrol), его профиль безопасности лучше по сравнению с E2. Однако он гораздо слабее эстрадиола. Но я немного недоумеваю, его сродство с ERß в несколько раз выше, чем с ERa. Я правильно понял? https://pmc.ncbi.nlm.nih.gov/articles/PMC8566418/
его аффинность связывания с ERα почти в 5 раз выше, чем у ERβ (таблица 2).
 

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losingbattle88

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Hope that one is at least better than the other.

I see some chaos on that video, and a bit of buildup but not too much. The redness is alarming tho, cause we know inflammation triggers hair loss.
Its actually sad that it has been so long and you still havent fixed your hairloss yet and still experimenting with stuff, It must have taken a toll on your life. U overdose on dutasteride, killed your balls.... I mean when will it end? Even when we solve hairloss we will never be truely satisfied with our selves and new problems will arise. Its a never ending story. We all are fixated on our appearance in this thread. We are all mentally sick. :(
 

coco_304

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Its actually sad that it has been so long and you still havent fixed your hairloss yet and still experimenting with stuff, It must have taken a toll on your life. U overdose on dutasteride, killed your balls.... I mean when will it end? Even when we solve hairloss we will never be truely satisfied with our selves and new problems will arise. Its a never ending story. We all are fixated on our appearance in this thread. We are all mentally sick. :(
agree
 

SnortingFinasteride

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Its actually sad that it has been so long and you still havent fixed your hairloss yet and still experimenting with stuff, It must have taken a toll on your life. U overdose on dutasteride, killed your balls.... I mean when will it end? Even when we solve hairloss we will never be truely satisfied with our selves and new problems will arise. Its a never ending story. We all are fixated on our appearance in this thread. We are all mentally sick. :(
Some people spit facts, you spit fire
 
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